Jun Wang

postdoc in epigenetic and cancer at Greg Wang lab, UNC - Chapel Hill.

[Jun Wang @james65799632]

Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader

https://t.co/GkyRsLMOvF

[Julia Joung @JuliaJoung]

Thrilled to share my primary PhD work: a Transcription Factor Atlas for understanding gene regulation and cell engineering @CellCellPress. We created a comprehensive TF ORF library and applied it to profile resulting expression changes. A thread 1/X https://t.co/PPcJ0HZEsW

[Oliver Bell @stanobell]

Excited to share our recent work about ZFP462, a TF associated with neurodevelopmental disorder, that is required for safeguarding neural lineage specification of by targeting the H3K9-specifc histone methyltransferase complex G9A/GLP to silence enhancers. https://t.co/uxzzwAmQUe

[ZeitlingerLab @ZeitlingerLab]

Previously, it has been a challenge to distinguish between motifs for TFs that drive chromatin accessibility and those that follow it. In our latest work from @kaelanbrennan and @MelanieWeilert, we tackled this problem in the early Drosophila embryo. (1/6)
https://t.co/7lq6NtguFu

[Alice Ting @aliceyting]

Can we perform unbiased discovery of endogenous proteins that traffick from one organelle to another in living cells?

Learn about our new proximity labeling method, TransitID, here:

Full video of ASCB lecture at https://t.co/kEEipZNKDs

[Jun Wang @james65799632]

@Liulab_UNC Congrats, Pengda. Great work!

[Jun Wang @james65799632]

Thrilled to make some contributions for this great project. Thanks @QingZhangLab and team. Great work!

[Qing Zhang @QingZhangLab]

Glad to share our paper @NatureGenet on a new histone modification regulating gene expression. Collaborations with many labs, including @DrBrianStrahl @QinYan1 @QiZhangLab @gregwan98641292 @utswcancer @UTSW_Pathology @UNC_Lineberger @UNC_BCBP 1/n
https://t.co/fcRJvlsOE4

[Qing Zhang @QingZhangLab]

Glad to share our paper @NatureGenet on a new histone modification regulating gene expression. Collaborations with many labs, including @DrBrianStrahl @QinYan1 @QiZhangLab @gregwan98641292 @utswcancer @UTSW_Pathology @UNC_Lineberger @UNC_BCBP 1/n
https://t.co/fcRJvlsOE4

[Jun Wang @james65799632]

Excited to share my second first-authored paper published online @NAR_Open . In prostate cancer, we found EZH2-TAD was critical for binding with AR/AR-V7 and both could be targeted by MS177 (EZH2 PROTAC). Thanks to all collaborators to make this happen.
https://t.co/QJ6OsPLsex

[Nature Biotechnology @NatureBiotech]

A novel antibody-guided and tagmentation-based method profiles chromatin-associated RNAs by detecting interactions in situ. #NBThighlight https://t.co/mijmML2akj

[Jun Wang @james65799632]

@QingZhangLab @PNASNews @UTSW_Pathology @utswcancer @UNC_Lineberger @liu_xijuan @jeremy_m_simon @ChenghengLiao Congratulations, Qing and team. Vey Nice work.

[Cell @CellCellPress]

Now online! Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases https://t.co/JbEsazWqCM

[Max Staller @maxvstaller]

My review went live today. I argue that transcription factors find their binding sites using both protein-protein interactions and DNA binding interactions. It's halfway between a review and a perspective. https://t.co/sZSeBPlKzw

[Arvind Panday & Lab @pandayarvind441]

CUT&RUN-qPCR- Greater Sensitivity and Spatial Resolution than ChIP-qPCR. Check out our method paper @STARProtocols from @ScullyRalph lab
https://t.co/Z5GnYkK95S

[Guillaume Laconde @Glaconde34]

ELIOT: A platform to navigate the E3 pocketome and aid the design of new PROTACs https://t.co/7mUwVKLMTD

[Varun Venkataramani @VarunVenkatara2]

Very happy to share our latest manuscript @CellCellPress with you: https://t.co/SpzebU9RIM
TL;DR: Glioblastomas are incurable brain tumors colonizing the entire brain. We overlay molecular and functional data to uncover a hijacking of neuronal mechanisms driving invasion.

[Trompoukilab @trompoukilab]

TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation | Nucleic Acids Research | Oxford Academic https://t.co/0y010ci8rl

[Cancer Cell @Cancer_Cell]

Online Now: Dark genome, bright ideas: Recent approaches to harness transposable elements in immunotherapies https://t.co/ssJCZufH4O

[Cell Press @CellPressNews]

"Glioblastoma hijacks neuronal mechanisms for brain invasion"

Read more in @CellCellPress: https://t.co/clMUJqZvKk

@HeidelbergU @VarunVenkatara2, Frank Winkler, Thomas Kuner

[Stanley Hsieh @Stanley_TH]

Here's a very detailed Micro-C protocol written by Elena (now @MIT) and @CCattoglio during our Micro-C workshop with @Anders_S_Hansen and @ViraatGoel! This protocol will make Micro-C work like a champ even if you've never done it before! Enjoy it :) https://t.co/0CJjKaiorg