James Lee and @DamienMorris have an interesting perspective paper out describing "some far-reaching conclusions" about the genetics of intelligence. This type of "where are we now" paper is very fun and more people should write them! So, where are we now? 🧵
In this preprint with Arun Durvasula, we discuss how there is no evidence for a bottleneck in the panmictic ancestral population of humans ~ 1 million years ago, as was suggested by Hu et al in Science last year
https://t.co/yLS1QDEEMk
It was recently reported that Africans experienced a sharp, severe bottleneck around 900kya and that this signal is absent in non-Africans. Here, we present evidence to show why this is likely a statistical artifact:
@ras_nielsen@yun_s_song
https://t.co/wH6p5VJrBl 1/4
Excited to share this new preprint with @spence_jeffrey_ and @DocEdge85 in which we developed a method to infer demographic history and mutation rates from millions of genomes, and applied it to gnomAD v4 data. Read on for a brief thread!
https://t.co/gLVQ77Sa5M
Second preprint from my group today---this one is led by @feriel_ouerghi_ . In this one, we discuss a previously proposed method for building forensic likelihood ratios from sequencing reads (1/n)
Two new preprints from my group today---this one was led by @Dandan_Peng with an assist from Obadiah Mulder. Dandan benchmarked a bunch of leading ARG-estimation methods with respect to a specific goal (1/n)
I'm excited to share this new preperint with @mwpen and @DocEdge85 about the unifying mapping approaches within and between species https://t.co/DOYLfRUHoB
Eugenic movement and scientific racism: past, present, and future #TAGC24
panelists: Katrina Claw, Nathaniel Comfort, Steven Farber, Daniel HoSang, and @Jazlyn_Mooney
Second time at #TAGC24/PEQG!
Presenting a poster tonight (785T) on my PhD work with @NoahARosenberg on mathematical properties of allele-sharing dissimilarities (and how they explain phenomena observed in human population-genetic data)!
Part 1 paper at https://t.co/LqhDiFQrx0
Trait differences
Q_{ST} and F_{ST}
Details can deceive
(Janis Liu, "Error rates in Q_{ST} vs. F_{ST} comparisons depend on genetic architecture") #sciku#evol2023@janisl98