@MARIARIVERO9376@SUQUI2024 Hola, en las conclusiones se habla de una estabilidad de los compuestos demostrada por los resultados RMSD y RMSF ¿Cómo pueden tener la certeza de que los ligandos no se desacoplan de la enzima durante los 100 ns de simulación? ¿Algún análisis complementario para verificar esto?
This is the most surprising and exciting result of my career: we were running simulations of NaCl with a neural network potential that implicitly accounts for the effect of the water, ie a continuum solvent model (trained on normal MD) when Junji noticed something strange: 1/n
You cannot get educated by this self-propagating system in which people study to pass exams, and teach others to pass exams, but nobody knows anything.
You learn something by doing it yourself, by asking questions, by thinking, and by experimenting.
The WHO added the “Mu” coronavirus variant to its list of “variants of interest” because it has the potential to evade immunity from vaccines and antibodies.
The variant was first identified in Colombia in January and now makes up 39% of all cases there.
https://t.co/29I6X1SkMT
Breaking News: The FDA granted full approval to the Pfizer-BioNTech vaccine, a first for a Covid shot in the U.S. It will pave the way for new vaccine mandates.
https://t.co/Uq1PhlxWPi
Ivermectin, an anti-parasitic drug commonly used for livestock, should not be taken to treat or prevent Covid-19, the FDA said on Saturday. https://t.co/ABc9AtUkXV
1/ Here is a comprehensive review of the data on whether we need COVID BOOSTER SHOTS.
THE MOST IMPORTANT TAKEAWAY:
IF YOU HAVEN'T YET GOTTEN A COVID VACCINE, NOW'S THE TIME!
I'll put a Threadreader unroll at the end for those of you who find that more convenient to read/share.
¿Preocupan las variantes?
Sí
¿Es una razón para no vacunarse?
No. ¡Al contrario!
Las variantes seguirán apareciendo en la medida en que haya más infecciones nuevas.
Por favor vacúnese apenas pueda, con la vacuna disponible.
No terminamos de asimilar a delta y ya apareció epsilon, con mutaciones de la proteína ‘spike’ que resisten a los anticuerpos generados por la vacunas tipo mRNA, es decir Pfizer y Moderna.
The epsilon variant of #SARSCoV2, first detected California, carries three spike protein mutations that confer resistance to neutralizing antibodies generated by mRNA vaccines or by #SARSCoV2 infection, according to new research in Science. https://t.co/w4il4EtrE5
“-Although plausible-” Esa pequeña posibilidad nos mantiene desinfectando sillas, alimentos, suelas de zapatos, etc, en lugar de esforzarnos en implementar medidas más efectivas como ventilar o purificar el aire
"The evidence is now clear. #SARSCoV2 is transmitted predominantly through the air — by people talking and breathing out large droplets and small particles called aerosols. Catching the virus from surfaces — although plausible — seems to be rare."
https://t.co/xCFprZviQ0 @nature
GameStop was worth about $2 billion in December. Now, largely thanks to enthusiastic amateur traders, it’s worth $24 billion.
We explain what's going on.
https://t.co/Tz92I2Stzw
#AcademicTwitter: I used to be a horrible scientific writer. I was paralyzed by writing anxiety & it took me FOREVER to write papers. Last year I published 14 scientific articles (8 first, 2 second, 2 senior-author) & 2 book chapters.
A thread⬇️on how I became more productive:
Enrolment in AstraZeneca / University of Oxford coronavirus vaccine trial on hold after suspected adverse event in trial participant. https://t.co/orLVYXuCMP
El petrismo:
Apreciados paracos, tibios, vendidos, uribistas, narcos, asesinos y corruptos del @PartidoVerdeCoL, @PoloDemocratico y @compromisociu. Los invitamos a que hagamos una coalición. 🌈
Researchers at Uniandes & Unicartagena have been examining peptides that can cross cell membranes because they can assist in drug treatments. We are proud to provide free compute resources that support their work. Learn more about #TechAgainstCOVID here: https://t.co/ADFf7c0mSt
Researchers have mapped glycan-processing states of the spike protein complex that allows the #SARSCoV2 virus to infect human cells – finding that SARS-CoV-2 S glycans differ from typical host glycan processing, which may inform vaccine design. https://t.co/N0l2k2LzSD