justin cisar

father, PhD scientist. #scienceworkssometimes

[justin cisar @jcisar]

@proteinqure This looks very nice!

[Armand @armandcognetta]

I'm an AI maximalist, but there's a wave of dumb ai bio companies that are being started because of this and I am very worried that they will lead to another biotech winter when they inevitably fail

many solutions in search of problems and other silly things

[justin cisar @jcisar]

@longlabstanford @OmicsOmicsBlog @NatMetabolism @DrYongXu1 @Shuke_Xiao Love this !

[Tom Moloughney @tommolog]

I think a LOT of people here feel similarly. Well done, and worth a read even if you don't believe you'll agree.

[Dan Nomura @DanNomura]

One of my close friends Jason Thomas is missing. If you see him or know anything, please reach out. https://t.co/3OFBA3UJlt

[justin cisar @jcisar]

@HartungIngo Link doesn’t work. Can you reshare?

[tbepler @tbepler1]

Huge thanks to our incredible team @openprotein, especially @timt1630. This is just the beginning of AI systems that truly understand protein biology.
I can’t wait to see what the community can do with these models. 13/13

[justin cisar @jcisar]

@RnaudBertrand Has Elon musk or Altman commented

[justin cisar @jcisar]

@armandcognetta @OmicsOmicsBlog @proxbio Congrats!

[justin cisar @jcisar]

This work gives us confidence in combining ADME models to calculate early human dose predictions and is being utilized in J&J discovery projects to help advance projects and facilitate decision-making.

[justin cisar @jcisar]

I am happy to share our efforts in validating an early human dose prediction method that can be used at the point of design. https://t.co/pODkVKzGxT

[justin cisar @jcisar]

Using a clever approach, Dries and the team demonstrated that the models we evaluated and propagated error allowed for ranking of compounds with 10-fold resolution. In the early drug discovery stage, this is very useful!

[justin cisar @jcisar]

I am happy to share our efforts in validating an early human dose prediction method that can be used at the point of design. https://t.co/pODkVKzGxT

[Dries Van Rompaey @d_vanrompaey]

Can we already start thinking about dose at the point of design? We discuss how we try to tackle this challenge and take a closer look at the impact of the accuracy of individual predictions.

https://t.co/CH7f2XuQI8

[Dries Van Rompaey @d_vanrompaey]

I’m truly grateful for the opportunity to work on a challenging problem with this all-star cast of (current and former) JNJ colleagues - at least a few of which I know to be on twitter @jcisar @jedward3!

[justin cisar @jcisar]

@longlabstanford @Keribackus Congrats !!

[justin cisar @jcisar]

Great event!

[Christopher Kelly @ckellzchem]

Last week, myself and Riley Svec (Global Discovery Chemistry at JnJ) had the absolute privilege to co-chair the 2024 JnJ Graduate Research Symposium and host 11 fantastic young chemists at our Spring House, PA Campus. All the students gave phenomenal talks and @KozlowskiMarisa gave a wonderful keynote lecture. It was a lot of work putting it all together (we had a lot of internal help!) but it was a highly successful event. Looking forward to all great things ahead for our GRS scholars...the future of synthesis is bright!

[Christopher Kelly @ckellzchem]

Last week, myself and Riley Svec (Global Discovery Chemistry at JnJ) had the absolute privilege to co-chair the 2024 JnJ Graduate Research Symposium and host 11 fantastic young chemists at our Spring House, PA Campus. All the students gave phenomenal talks and @KozlowskiMarisa gave a wonderful keynote lecture. It was a lot of work putting it all together (we had a lot of internal help!) but it was a highly successful event. Looking forward to all great things ahead for our GRS scholars...the future of synthesis is bright!