General Proximity

The next generation of induced-proximity medicines.

We're here to put a dent in the universe.

[Armand @armandcognetta]

induced proximity is the future of medicine

and we've barely scratched the surface of what's possible with it...

there is simply no other modality that combines the versatility of small molecules with the power of much more complex next-gen therapeutics

[General Proximity @proxbio]

Welcome to Team GP Andreas Maderna!

[Armand @armandcognetta]

Excited to announce an investment in General Proximity (@proxbio) from Daewoong Pharmaceutical and FMI showing continued strategic partner interest!

https://t.co/27ZCsYyrgx

[Armand @armandcognetta]

Announcing General Proximity's $12M, 2x over-subscribed, pre-Series A round.

Medicine is in the dark ages. Our understanding of biology far exceeds our ability to perturb it therapeutically.

[Armand @armandcognetta]

There’s an enormous gap in the longevity field that almost no one is talking about.

No existing therapeutic modalities are capable of both systemic distribution and complex transformations.

Until we solve this, we won’t solve aging. 🧵

[Armand @armandcognetta]

Proud to announce our collaboration with @DaiichiSankyoUS to leverage our OmniTAC platform to identify novel Induced Proximity Medicines!

[Armand @armandcognetta]

GP is hiring! Come join the dream team @proxbio🚀

https://t.co/5yD7GEtlpW

[Armand @armandcognetta]

this was a super fun convo!

got to talk about a bunch of things that I've been obsessed with for a long time:
-the inner work of fundraising
-the magic of doing hard things
-how to have great ideas
-being a solo founder
-fantasy novels as meaning-makers for founders :)

[Armand @armandcognetta]

one mistake early founders often make is that they think they should be able to accurately assess every single candidate in a recruiting process

unfortunately the candidates where you have high s/n is somewhat stochastic, based on your experience so far

[Dave Messina @DaveMessina]

"most start-up founders should probably be more ambitious. Start-ups are extremely hard. Don’t waste your life on something trivial."

Killer post from @armandcognetta

[Armand @armandcognetta]

I'm looking to bring on our very first senior leadership role in drug discovery (Sr. Director/VP) at General Proximity. We have an insanely high talent density team (https://t.co/5Tir47FzrC) so the bar for this role is extremely high.

DM if you think you might be a good fit

[Armand @armandcognetta]

I'm always surprised by how many health-focused biotechs and labs feed their team pizza, bagels, and donuts.

We try to do things a little differently at @proxbio, with benefits from Locale, @function health, Nebula Genomics, and @onemedical, as well as a number of other benefits and incentives to help our team members reach peak performance.

https://t.co/Jvg5IJQLnc

[Nathan S. Cheng thinks you should work on aging. @realNathanCheng]

Proud to be an investor of General Proximity! @armandcognetta is one of the most talented and incredibly tenacious founders I know.

[Olivia Wang @OliveWang839]

Armand's rare combination of grit, vision, and execution through the years has been incredible to witness. Excited for this launch and the chapters to come!

[Aydin Senkut @asenkut]

So excited to lead @proxbio seed and partner with @armandcognetta - he’s on to something really big here ! 🤩🔥🚀👇🏻

[Armand @armandcognetta]

General Proximity (@proxbio) is coming out of stealth.

General Proximity is developing a new class of medicines that we believe has the potential to decrease global disease burden, transform human health, and extend lifespan more than any other current therapeutic modality. 🧵

[Armand @armandcognetta]

+1. We need to normalize founder-led start-ups that incorporate to generate brand new tech/IP.

I got so much confusion and pushback from VCs when I first started my co to develop a brand new therapeutic modality + associated tech from the ground up

[Armand @armandcognetta]

So honored to share that @proxbio was one of the 23 awardees (out of 1700+ applicants!) for the @ARPA_H #SprintForWomensHealth!

This $3M grant will support our team as we advance next-gen proximity therapeutics for high value undruggable targets in the women’s cancer space towards the clinic.

Dedicating this work to my incredible mother, Suzanne Cognetta. I began working on cancer therapeutics after she was diagnosed with breast cancer for the second time and I realized that despite being in one of the best chemical biology labs in the world, I was powerless to help her.

Hopefully our work here will be a big step towards changing that for all the women and mothers in the world.

[Armand @armandcognetta]

Inbound to @KeystoneSymp Proximity Based Therapeutics with proximity legend @MichelleArkin et al

[Armand @armandcognetta]

Happy to share that @WeatherwaxBio has won the 2022 Bristol Myers Squibb Golden Ticket! @bmsnews has been a long-time leader in induced-proximity medicines and our team looks forward to leveraging their deep experience as we begin to progress molecules towards the clinic 🚀