Jelena Perovanovic

Computational biologist on a quest to discover new medicines. Mom, traveler, music fan.

[Recursion @RecursionPharma]

📆New year.
📽️New 101 video.
🚀Same relentless ambition.

➡️ See you at #JPM26!

[Recursion @RecursionPharma]

🧠 How the Microglia Map will help guide new insights and therapeutic pathways for treating neurodegenerative diseases.

In a new story in @Tech_Networks, incoming CEO and President Najat Khan, PhD shared insights into the creation of the Microglia Map in partnership with @Roche and @genentech, and what it could mean for future drug discovery.

▪️ On why this is such a significant breakthrough.

“By performing a whole-genome screen on >17,000 genes, it enables researchers to look at the unexplored biology around the known ‘bright spots,’ driving the discovery of completely novel genes and pathways for first-in-class therapies.”

▪️ On the challenges of producing over 100 billion hiPSC-derived microglia.

“The team had to develop and scale new cell manufacturing techniques in order to produce enough microglia for the map, and to produce them in a standardized way, something that had never been done before. Microglia can be highly variable from batch to batch – and are very sensitive to their environment, changing states from relatively stable to becoming more reactive and inflammatory. The team successfully confirmed that the microglia we started with were as stable as possible, which allowed us to reliably compare all the map perturbations against one another.”

▪️ On what to expect from the Microglia Map.

“There’s a massive need for new targets and new therapies in neurodegenerative diseases and I believe these maps will serve as an important starting place for significantly expanding those opportunities.”

👉 Read the article: https://t.co/Jhw4XEZg88

[Arhiv javnih skupova / Public Assembly Archive @javniskupovi]

Beograd, 18:00

[N1 Beograd @n1srbija]

Hor otpevao pesmu "Zemlja" legendarnog EKV

[Igor Vujanović @Infoverzum]

"Gde god da odem taj grad me prati, Beograd moj sebi me vrati" ♥️🇷🇸

[Recursion @RecursionPharma]

Great to see our partnership with @Roche and @genentech featured on the main stage at #AACR24 during Aviv Regev's plenary talk!
#techbio #oncology #biotech

[Recursion @RecursionPharma]

🧠 Did you know that we’re one of the world’s largest producers of neuronal cells? Since 2022, our platform has generated more than 1 trillion hiPSC-derived neuronal cells - the equivalent number of neurons in over 10 human brains! 🤯
#techbio #biotech
Check out more our annual report! https://t.co/Eyjw8kueED

[Patrick Hsu @pdhsu]

Is DNA all you need?

In new work, we report Evo, a genomic foundation model that learns across the fundamental languages of biology: DNA, RNA, and proteins. Evo is capable of both prediction tasks and generative design, from molecular to whole genome scale.

[Jelena Perovanovic @jelenapero]

@realmilancurcic @MiamiRosenstiel @UMIDSC Great news! Bravo Milan!

[Jelena Perovanovic @jelenapero]

@DvdGently @RutterLab @Nature @Intein Q

[Recursion @RecursionPharma]

Great segment from @SquawkCNBC about #AI in #drugdiscovery this morning!

Thanks to @ScottGottliebMD for including us in the conversation. Watch ⬇️ #biotech #techbio

[𝓚𝓼𝓮𝓷𝓲𝓳𝓪 @XeniaKsenija21]

I slika i ton

[Science Signaling @scisignal]

Scientists delineate how the protein Oct1 enables #EmbryonicStemCells to differentiate into the #mesoderm—clarifying a key step in development and potentially assisting efforts to engineer cells for regenerative medicine. @jelenapero @UofUMedicine https://t.co/GTSqJ6mib7

[Science Signaling @scisignal]

How do embryonic stem cells transition into mesodermal tissue? Using mouse cells, researchers show Oct1 binds at mesoderm-specific genes and cooperates with Smad proteins to trigger gene expression and differentiation. #DevelopmentalBiology @jelenapero https://t.co/citTV5ixCJ

[Recursion @RecursionPharma]

We are proud to announce that we have been named to @FastCompany's Most Innovative Companies list in the #Biotech category for our unbiased, #ai-enabled approach to #drugdiscovery.

Learn more about why we're recognized: https://t.co/0RL3WSl3sD #techbio #FCMostInnovative

[Goran Vukajlović @sofi2022_2023]

Ima jedna lepa priča koju je ispričao Ričard Dokins: "Kad sam bio student, impresionirala me je reakcija jednog veoma poštovanog starijeg naučnika sa Oksfordskog odeljenja za zoologiju, kad je posetilac iz Amerike javno oborio njegovu omiljenu teoriju. Stari naučnik je krupnim ⚡️

[Recursion @RecursionPharma]

Today we released our first-ever public Map demonstration, which dives into our process for navigating complex biological relationships to uncover potential new treatments for patients.

Join Founding Fellow, Mason Victors for a step-by-step tutorial: https://t.co/F3g6K88jPL

[Children's Tumor Fdn @ChildrensTumor]

>>NF2 #ClinicalTrial Opportunity<<
If you are 12 years or older + have #neurofibromatosis type 2 (#NF2), you may be eligible to participate in a study investigating the safety & efficacy of an investigational drug

More at https://t.co/9HqFm2t7C5

@RecursionPharma #endnf

[Recursion @RecursionPharma]

Fueled by 19 petabytes of data and one of the world’s most powerful supercomputers, Recursion is changing how we think about #drugdiscovery.
Learn how we’re decoding biology to radically improve lives in our newest Recursion 101 video 👇