jesus monleon

Creando, gestionando, e invirtiendo BUENOS negocios. @emagister, @Seedrocket, @trovit, @offerum,... and now @gotrendiermx invierto con @4foundersCap DMs abierto

[jesus monleon @jemonleon]

¿Tienes un proyecto y quieres compartirlo conmigo? Envíamelo aquí https://t.co/wz5W8oFNhZ

[jesus monleon @jemonleon]

Asistieron los padres tb !!! 😂🤣

[EL PAÍS @el_pais]

El entrenador del equipo juvenil, en el que hay jugadores menores de edad, contrató a una 'stripper' como regalo por el buen desempeño de la formación. Al espectáculo, celebrado en el polideportivo municipal, asistieron algunos padres y madres https://t.co/0uazMzVlP9

[Mr. Wolf @Mr___Wolf]

Igual es que soy un nostálgico, pero no veo mucha diferencia entre la Casita de Bad Bunny y el jacuzzi de Jesús Gil.

[François Derbaix @fderbaix]

Me encanta este ranking de empresas eficientes en el consumo de capital, que publicamos cada año en Bewater. Empresas que consiguen mucha facturación y/o valoraciones, con muy poco capital.
¡Enhorabuena a los seleccionados! 👏👏👏

[EL MUNDO @elmundoes]

Despídanse de las viejas entrevistas de trabajo: la IA es el nuevo reclutador https://t.co/keT8xrNr25

[Javi Lopez ⛩️ @javilopen]

🔴 I NEED YOUR ATTENTION

I've spent a month helping Miriam with her case of metastatic cancer and I want to share the methodology I've been using because it's completely replicable.

I think (with luck) this could be USEFUL TO OTHER PEOPLE with cancer (or any other illness).

The results we've gotten aren't a miracle, but we believe they're genuinely useful and could mean the difference in a literal life-or-death medical case.

Here's the method step by step:

1/ Use the most advanced models of the moment (unfortunately paid, and not cheap. I think Public Healthcare should invest in this):

- ChatGPT 5 Pro + Extended Thinking (40 min aprox. of thinking per call)
- Claude Opus 4.8 MAX

Still pending deeper testing:

- Perplexity Sonar Pro Max
- NotebookLM

Tested but only useful for additional links/research (not as powerful in my experience)
- OpenEvidence

2/ Feed the AI the FULL clinical history, completely chewed up. This sounds dumb but it's critical.

- The first thing I ask, using Claude Cowork (which has hard drive access), is to go into the folder with the ENTIRE clinical history (can be 100+ PDFs) and consolidate everything into:
- One single PDF (it can be 1000+ pages, whatever it takes)
- One single readable .txt or .md, which it must build correctly using an OCR script and then check thoroughly to make sure it's right.

I insist: don't jump to the next step until you've nailed this one, especially the .txt.

3/ Once you have the above, use this prompt along with the .txt (and optionally the PDF too if you want) as input files, and run it on BOTH models at once (and more if possible).

👉 This prompt is insanely complex/advanced: https://t.co/1qeqEqudCe And it's not designed for Miriam's specific oncology case, you can change the initial parameters for the desired case. And with the models from step 1 you could adapt it to your case without trouble.

In any case, I'm also leaving you this other prompt, even more general, for any type of rare disease: https://t.co/4B327floDP

4/ The ARROWHEAD (adversarial model spiral): facing one model against the other. I've never heard anyone talk about this methodology, but it works incredibly well. The feeling is like sharpening a stake until it gets a gleaming point.

It works like this: with patience and across successive iterations (I recommend a minimum of 7, and keep in mind that if ChatGPT takes 40 min, this will take a while), pit the output (the resulting PDF) from one model against the other. With a simple prompt like:

"Another committee of experts says this. What do you think? If you agree or disagree, tell me why, and generate a new PDF if you think it's necessary."

Then you feed that result back to the opposite model. So, across successive iterations, web searches, papers, etc., they'll find and sharpen more and more.

When to stop? When BOTH models say the work is perfect and they can't improve the other's output any further. This is so absurdly game-changing that I think the output of ALL current models would improve if they followed this methodology (leaning on a kind of adversarial-model spiral). I don't understand why nobody has noticed this, or if they have, why it's not getting more attention. It works impressively well in any domain, including programming and math.

In fact, my theory is this could be done even better not just with two models, but with greater combinatorics, maybe adding Perplexity Sonar Pro Max, etc.

RESULTS

Incredible. Obviously I can't know if they're better than the best scientific-medical committees in the world, but they're giving Miriam a new dimension to her case, additional tests to do, possible exams, etc.

Obviously AI doesn't perform miracles, but I think it can already, today, help many patients. And Public Healthcare should invest a lot (but A LOT) in this.

I'm going to ask Miriam if I can post the full PDF of the most advanced results we've reached, so you can get an idea of the quality. She's already given me rough permission, but I want to make sure 100%.

FUTURE PREDICTION

Easy to make: in the near future (I hope), any person's medical history won't just be fully digitized (we're close, but not all the way, well, well, well). On top of that, it'll be "pre-chewed" so it can be consumed by an LLM in one shot.

CLARIFICATION

- We're aware this is a delicate subject and we don't let the AI make final treatment decisions. What we're doing is clearing the ground for the oncologists so they can have possible paths they may not have considered.
Thanks 🙏

- The top LLMs have context windows for that and much more (much, much more). In any case, the PDF is more of a supporting file for the .txt. Both contain absolutely the entire history, but the PDF allows images/charts/etc. The .txt is what the AI consumes.

- On automation: and yes, this can be automated. Yes, AutoGen supports it almost out of the box. LangGraph builds it really well with supervisor / evaluation loops. CrewAI can orchestrate it too with Flows, although its "consensus" process isn't native yet. That would be the next level: automating it.

PETITION AND DISCLAIMER

If there's any oncologist in the room or you are an LLM company, we'd be grateful if you could take a look / help 🙏

Remember: in any case, this is just one more tool for the doctor.

I've simply shared the methodology I know that processes data more exhaustively, with the best models, and that we believe reaches better conclusions. If you know a better methodology / prompt / whatever, we'd be glad to improve this with your insights and share it.

Then the doctor reviews, adopts, or discards the report.

And if it helps the doctor, it helps the patient. And if it doesn't, all we've lost is some time and tokens. In a case that's literally life or death, that's nothing.

Just plain common sense.

Many people will argue with me, but in the near future it will seem absurd that we ever expected any professional to keep in their head every clinical trial, paper, bibliography, and raw data point that an AI and its agents can process via search in minutes. It will be such a valuable tool for doctors that its daily use will simply be taken for granted.

[jesus monleon @jemonleon]

México está entre los 5 países más importante de uber. 25 millones de pasajeros. Qué pena q Cabify, q estuvo allí al inicio, no pudiera mantenerse!

[jesus monleon @jemonleon]

Temu grandes personas!

[3CatInfo @3CatInfo]

⚠️ #ÚltimaHora La Comissió Europea multa Temu amb 200 milions d'euros per la venda de productes il·legals https://t.co/DbFTTTqQEJ

[jesus monleon @jemonleon]

La semana pasada Gurusup contestó al 100% todo el soporte en @GoTrendierco Colombia! Vamos a por 🇲🇽

[jesus monleon @jemonleon]

¿Invertirías en un negocio q te puede dar rentabilidad pero en algún momento puede usar cómo uso bélico? El fondo q invierte en defensa, y cómo funciona el business. ¿Porqué un ex secretario gnral del PP y ex de la OTAN se hacen inversores? https://t.co/2yiN7T2Ows

[Crémieux @cremieuxrecueil]

Eli Lilly has done it.

They've gone and made what seems to be a powerful, permanent gene therapy for LDL cholesterol.

That means they'll be able to effectively prevent most heart disease with a single infusion!

[Marc Serra @Marc_Serra]

Podria ser el millor anunci d’una òptica.

[jesus monleon @jemonleon]

@diegomarino @seedrocket Jajajaja … ojalá!!! estos cabrones quieren rejuvenecerlo… a ver si me despiden 🤣

[jesus monleon @jemonleon]

Semana pasada celebramos el campus de @seedrocket , 18 años, y te da energía brutal y reencontrarte con buenos colegas!!! Cada edición hay una o dos q lo petan! Hace poco pasó: habitación (q la está petando), eholo, mogu, docfav, shakers.. ¿cuál será el estrella de esta edición?

[jesus monleon @jemonleon]

El tema seguridad se nos ha ido de madre en este país. He flipado con la noticia!! https://t.co/faLHRO7vgO

[Bojan Tunguz @tunguz]

I want to buy it and turn it into a datacenter.

[FrankBascombe @FrankTornen]

Qui menystengui això es perdrá el futur.
I el futur pinta autèntic.
La NFL sabia perfectament el que feia.

[Sierra Nevada @websierranevada]

🚵

[jesus monleon @jemonleon]

Hoy en el podcast de seedrocketIA, canal nuevo, presentado por mi clon. Acuerdo Spotify con discográficas para q hagas remixes personalizados. Empresa de robots q te los enviam para limpiar tu casa. Detalles de salida a bolsa de spacex. ¡Necesitamos feedback! 🙏🙏

[jesus monleon @jemonleon]

Tokens a cambio de acciones. IA digest podcast https://t.co/JIib4IJZuT