Jie Chen

😀

[Jie Chen @jiechen1982]

It’s a team work. Thanks for everyone’s effort!

[Shen-Ying Zhang @ShenYingZhang1]

Our new study of inborn error of TLR3 or MDA5 in two children with enterovirus encephalitis suggests that TLR3 and MDA5 may spatially and sequentially control anti-enterovirus immunity in CNS cells, via the maintenance of basal or virus-induced IFN-a/β or -λ levels, respectively.

[Shen-Ying Zhang @ShenYingZhang1]

Our new study of inborn error of TLR3 or MDA5 in two children with enterovirus encephalitis suggests that TLR3 and MDA5 may spatially and sequentially control anti-enterovirus immunity in CNS cells, via the maintenance of basal or virus-induced IFN-a/β or -λ levels, respectively.

[Rockefeller University @RockefellerUniv]

Dr. Jean-Laurent Casanova (@casanova_lab) and President Rick Lifton share the latest #COVID19 findings: how misguided antibodies and specific genetic mutations may explain a significant percentage of severe and life-threatening responses to SARS-CoV-2: https://t.co/mVNfF1jAeb

[Casanova Lab @casanova_lab]

We have been silent for a while because our lab and the CHGE were entirely focused on finishing 'twin papers' in @ScienceMagazine about inborn errors of type I IFN or auto-antibodies to type I IFN in nearly 15% of patients with life-threatening #COVID19 😀 https://t.co/E85pF1Kg88

[Jie Chen @jiechen1982]

Amazing! Proud of our dream team!

[Casanova Lab @casanova_lab]

We have been silent for a while because our lab and the CHGE were entirely focused on finishing 'twin papers' in @ScienceMagazine about inborn errors of type I IFN or auto-antibodies to type I IFN in nearly 15% of patients with life-threatening #COVID19 😀 https://t.co/E85pF1Kg88

[Belot Alexandre @AlexandreBelot]

Type I IFN immunoprofiling in COVID-19 patients https://t.co/Y2jdwxLZYv
Our findings highlight defect of IFN-I in COVID-19 patients and suggest recombinant IFN could be beneficial in patients especially within the first week of SARS-CoV2 infection.

[Jie Chen @jiechen1982]

Fantastic work,congratulations!

[Pan-Hammarström lab @panhammarstrom]

Non Covid-19 note: together with colleagues at TMDU, we identified the very first APRIL deficient patient. Our study suggests a role of APRIL in life-long plasmacyte maintenance and Ig production in humans. https://t.co/X3toRZzidq

[Jie Chen @jiechen1982]

@casanova_lab I’m so proud of being an member of our lab fighting against COVID-19, please join us and visit https://t.co/ajwwFyIgQj! #COVID19 #SARS_CoV2 #COVIDHumanGeneticEffort