Años usando la miocarditis para asustar con las vacunas de ARNm contra la COVID-19.
Nuevo estudio: más de 4 millones de jóvenes. Mayor riesgo de miocarditis, pericarditis y muerte en no vacunados tras COVID-19.
Los datos tienen la costumbre de desmontar a los antivacunas 🧵
We just crossed a line in medicine that humanity has been walking toward for a hundred years.
For the first time, doctors can take a biopsy of your specific tumor, read its unique DNA mutations — the exact fingerprint no other cancer on earth shares — and build a custom mRNA blueprint written for one human being. Yours.
It doesn't poison the cancer. It teaches your own immune system what to hunt.
And this week, Phase 3 results confirmed it works.
Added to the best immunotherapy we already had, this individualized cancer vaccine has been dramatically cutting the odds that high-risk melanoma comes back. In the earlier data, the combination reduced the risk of recurrence or death by 49%, and the risk of the cancer spreading to distant organs by 62%, compared to the standard treatment alone. This week's Phase 3 readout confirmed the benefit holds. That is not a modest tweak. That is a different trajectory for a human life.
And melanoma is just the first door. The same approach is now in trials across lung, bladder, and kidney cancers — a whole program of them, racing forward.
Understand what this actually means, because it's bigger than one drug.
For all of history, we fought cancer with blunt weapons. Cut it out. Burn it with radiation. Flood the whole body with chemotherapy and hope the cancer dies before the patient suffers too much. We were swinging a hammer in the dark.
This is a blueprint. A weapon designed atom by atom for one person's disease, that turns their own body into the thing that finds and destroys it. We are watching medicine shift from managing cancer to hunting it.
I've spent my life as a physician, and I did not expect to see this so soon. We were told personalized cancer vaccines were a thirty-year dream. They are happening right now, in real patients, with real data, in our lifetime.
I don't say this lightly, and I say it as a doctor who knows exactly how rare these moments are: this is one of the most hopeful things to happen in the history of the field.
I woke up thinking of the words of the morning prayer — Modeh Ani — I thank You. Gratitude, the moment you open your eyes, for a soul returned and a day given. To be alive at the exact hour when human beings learned to teach the body to cure itself feels like standing inside that prayer.
We are not at the end of cancer. But we are, unmistakably, at the beginning of the end of its reign.
Caleb, Caleb, Caleb. Caleb this. Caleb that.
I went to Chicago to write about the parts of the Bears offense that *aren’t* the quarterback
READ: https://t.co/4LpAioJxos
@Ky1eLong 90% here. I’m thrilled it worked out, especially with Poles’ history drafting and signing O-lineman, but Jalen was still the right choice. Wright is not an LT & DT is the linchpin of a good D. Bears D line has been awful. Jalen just needs support/maturity & will be best DT in NFL
@GOGOSuperJoe Davis should be in the bullpen. Fedde has been better recently. Davis is reminding me of the end of Giolito’s tenure with us where he lost velocity and effectiveness of his pitches. The coaches thought he was tipping his pitches and could not figure out how to fix him.
Politico reports that GOP members of Congress can't find smart young conservatives to work for them.
Senior GOP congressional staffer:
“Everyone knows what the problem is: The organizations that bring young staffers to Washington, D.C. have spent the last decade prioritizing blind ideological loyalty instead of competence or intelligence. We have a generation of rabid, incompetent idiots.”
Joe Kernen comes close to having a coronary on air as Pete Buttigieg dogwalks him all over the Squawk Box studio about Trump's economic mismanagement and inflation
@Chicago_NFL@ChiSportsSteve His source is Kevin Warren or Mccasky; and Schefter is being used. Shame on Schefter to let himself be used as a pawn in this amateurish game the Bears are playing. IL politicians are pros and everyone knows the Bears have zero leverage.
Gov. Pritzker on some of the Bears’ “fumbles” in Springfield. He also said that “if the legislature can get together on one piece of legislation,” he would be “happy to call a special session.”