Jonathan A. Nowak

Molecular and GI pathologist. Assoc director, BWH Center for Advanced Molecular Diagnostics. @BrighamWomens @BWHPath @DanaFarber @harvardmed Views are my own.

[Jonathan A. Nowak @jonathan_nowak]

Excited to head to ASCO GI next week to present our work on the prognostic and predictive role of ctDNA in stage III colon cancer in the 80702 clinical trial. Thanks to @ASCO for kindly considering our late-breaking abstract. @ALLIANCE_org @DanaFarber @NateraOncology #GI25

[Jonathan A. Nowak @jonathan_nowak]

@CentralParkWMD Looks so peaceful at 5 AM! I miss running in NYC.

[Jonathan A. Nowak @jonathan_nowak]

@DrJashDatta @SylvesterCancer @DrSDNimer @umiamimedicine @UMiamiHealth @UMiamiMedNews @JTrentMDPhD @DrOlaLandgren @JaimeMerchan10 @UMJMHSurgery @PeterHoseinMD @NbmerchantMD Congrats Jash! Very well deserved. Look forward to seeing what you accomplish.

[Anirban Maitra @Aiims1742]

NCT06445062: Revolution Medicines trial combining RMC-6236 with either FOLFIRINOX or Gemcitabine/nab-paclitaxel in treatment naive #PancreaticCancer. This study is now open at 17 locations nationwide. Also includes sub-cohorts for #ColorectalCancer and 2nd line pancreatic cancer.

[Jonathan A. Nowak @jonathan_nowak]

Thrilled for the Wolpin-Nowak lab to be part of the correlative science team for this cohort! An amazing opportunity to conduct great science using human specimens to rapidly improve RAS inhibitor use in PDAC.

[𝗕𝗿𝗲𝗮𝗸 𝙏𝙝𝙧𝙤𝙪𝙜𝙝 𝗖𝗮𝗻𝗰𝗲𝗿 @break_cancer]

We are excited to have launched an expanded Phase 1 trial cohort for pancreatic cancer with Revolution Medicines. This trial uses serial biopsies and blood samples to analyze tumor response to RMC-6236 at an unprecedented level of cellular detail

Read more here: https://t.co/6cGL8TEnKa
#PancreaticCancer#RadicalCollaboration

[Robyn Temple-Smolkin @Robyn_Temple]

Thank you #AMPath24 Program Cmte, all our exhibitors & sponsors, speakers, attendees, volunteers, and the @AMPath team for another truly amazing meeting. Thank you #Vancouver for being such a wonderful host city. Save the dates now for #AMPath25 Boston! #beantown

[Jonathan A. Nowak @jonathan_nowak]

So many opportunities to learn from long range sequencing approaches. Great perspective on the current landscape and personal experience presented by @sedlazeck @BCM_HGSC at #AMPath24. @AMPath

[Jonathan A. Nowak @jonathan_nowak]

Thought provoking Solid Tumor plenary session at #AMPath24 by Peter Sorger @harvardmed on insights gained from and opportunities presented by spatial tissue profiling and ML. Also so many beautiful images. @AMPath

[Jonathan A. Nowak @jonathan_nowak]

Amazing input requirements and performance characteristics for internally developed clinical WES at @DHMCandClinics pathology. @LJTafeMD at #AMPath24. @AMPath

[Jonathan A. Nowak @jonathan_nowak]

Standing room only for @ColumbiaPath Dr. Susan Hsiao presenting on clinical cancer exome sequencing and transcriptome profiling for pediatric patients at #AMPath24. Amazing that her lab has been doing this work for nearly a decade. @AMPath

[Jonathan A. Nowak @jonathan_nowak]

How can tumor-derived evidence improve classification of germline variants in cancer patients? The INT2GRATE consortium showcases a solution. Presented by @BWHPath Arezou Ghazani at #AMPath24 genetics selected abstracts session. @AMPath

[Jonathan A. Nowak @jonathan_nowak]

New to @AMPath and want to get involved? The Membership Affairs Committee has prepared this excellent visual guide for you! According to this, I like people sometimes, and planning, but not money. Also like big events. #AMPath24

[Jonathan A. Nowak @jonathan_nowak]

Happening now at the AMP annual meeting: Professional Relations Committee addressing AMP’s lawsuit against the FDA challenging oversight of LDT procedures. Very grateful for the deep expertise on this panel. @AMPath #AMPath24

[Jonathan A. Nowak @jonathan_nowak]

Thrilled to kick off the 30th annual AMP annual meeting in Vancouver earlier this morning! Thanks to our Program Committee members and AMP staff for putting together a great agenda for us.

[Panieh Terraf @p_terraf]

@jonathan_nowak kicking off the amazing #AMPath24! @AMPath

[Association for Molecular Pathology @AMPath]

🌟 Let's support our #AMPath24 Host City! 🌟 This year, AMP will contribute a $5,000 charitable donation to the PHS Community Services Society which aids under-served people in Vancouver and Victoria. 🤝 Learn more at https://t.co/miezh6tz2V

[Jonathan A. Nowak @jonathan_nowak]

Great start to the @break_cancer 2024 summit hosted by @MDAndersonNews in Houston! Looking forward to the next two days. #RadicalCollaboration

[Jonathan A. Nowak @jonathan_nowak]

@AlannaChurch_MD Congrats Alanna. That is a very Brookline sticker!

[Jonathan A. Nowak @jonathan_nowak]

Wolpin-Nowak lab entry into the @DanaFarber pumpkin decorating contest. We started with an mIF image of the PDAC TME then used AI to render as a skull with a Dia de Los Muertos theme. Hand painted by the amazing Bridget Cahill of the Rosenthal lab. Happy Friday everyone!

[Jonathan A. Nowak @jonathan_nowak]

Thank you, @ALLIANCE_org, for the recognition of our team. Large multi site trials like C80702 provide such a wealth of high impact data for patient care. Look for our ctDNA results coming early next year!

[Alliance for Clinical Trials in Oncology @ALLIANCE_org]

Congratulations, Cynthia Ma, MD, PhD @WashuOnc et al and @jonathan_nowak @DanaFarber et al, for receiving Honorable Mention - Most Significant Alliance Manuscripts, 2023-2024! https://t.co/fB2KG3aVHY & https://t.co/xRclG6R53w #AllianceFall24 #NCI #NCTN #CancerResearch

[Jonathan A. Nowak @jonathan_nowak]

Thanks for highlighting our lab’s classic KRAS assay @JMDiagn! Served us well for more than a decade. Pyrosequncing traces were always such fun little puzzles. Might be dating myself, but we were still running this assay when I was an MGP fellow.

[The Journal of Molecular Diagnostics @JMDiagn]

#25for25 #JMDSilver

7. Sensitive Sequencing Method for KRAS Mutation Detection by Pyrosequencing. Authors from @Brighamwomens, @Danafarber, @HarvardMed, @Biotage, and @MassGeneralNews.

Published in 2005. Cited 454 times.

https://t.co/pySJWlRxl1