Joy Fan

PhD candidate in BME @Columbia | computational #cancer research at

[Joy Fan @joy_lfan]

#Echidna is now publicly available at https://t.co/9510iBUZZN..., and may also be installed through PyPI and Bioconda! We hope you will join us in understanding the role of CNAs in phenotypic plasticity!

[Joy Fan @joy_lfan]

🧵 Excited to share #Echidna, a Bayesian framework for quantifying the impact of gene dosage on phenotypic plasticity: https://t.co/ypjP8Zins0!
With @elhamazizi & @mingZedh, we integrate scRNA-seq & WGS to uncover how CNAs drive tumor evolution and transcriptional variability.

[Joy Fan @joy_lfan]

📢 TL;DR: #Echidna 🦔integrates scRNA-seq & WGS to decouple gene dosage effects on phenotypic plasticity, tracks clonal evolution, and identifies resistance drivers in tumors.
Read more here: https://t.co/rDq1pZU9iY
Let’s unravel tumor evolution, one clone at a time! 7/7

[Elham Azizi @elhamazizi]

Check out our comment piece with @joy_lfan @AchilleNazaret on breakthroughs in #AI for studying the tumor microenvironment. Thanks to @naturemethods for the opportunity!
@ColumbiaBME @Cancer_dynamics @CUSEAS @columbiacancer

[Joy Fan @joy_lfan]

So thankful for this opportunity and for the support of @Cancer_dynamics and @elhamazizi ☺️

[Columbia - Irving Institute for Cancer Dynamics @Cancer_dynamics]

Thrilled to announce that Linyue (Joy) Fan @joy_lfan, PhD student in biomedical engineering, @elhamazizi, has been awarded the prestigious #AvanessiansFellowship for the 2024 Spring semester! 🏆 Join us in congratulating Joy on this recognition! 👏

[Joy Fan @joy_lfan]

So grateful to collaborators @AchilleNazaret @elhamazizi @vp_lavallee @dana_peer for leading this project with me, and many others for their contributions!

[Joy Fan @joy_lfan]

Unveiling the power of #Decipher , a game-changing method for integrating and visualizing #singlecell RNA-seq data! 👩‍🔬 Our work sheds light on cell-state transitions in diseases like #AML. Join the conversation in the thread and check out our preprint for the full story!

[Achille Nazaret @AchilleNazaret]

1/🧵 Excited to share #Decipher 🔍, a game-changing method for integrating #singlecell RNA-seq data 🧬 from multiple conditions and revealing cell-state transitions in diseases like #AML. Dive into our thread for more! Check our preprint for full details. https://t.co/gb8MM1LlAm

[Columbia - Irving Institute for Cancer Dynamics @Cancer_dynamics]

In the latest "Faces of IICD" blog series, Joy Fan (@joy_lfan) shares about balancing out multiple roles as a musician, artist, writer, and scientist.

Link: https://t.co/lObp7iIyxK

cc: @elhamazizi @ColumbiaBME

[Columbia Engineering @CUSEAS]

Researchers @Columbia have invented a multimodal RNA sequencing method that achieves high-quality results from small volumes of frozen cancer tissues. https://t.co/Dn5zFT9pCt @ColumbiaMed @ColumbiaScience @ColumbiaBME @elhamazizi @BizarMd @joy_lfan @JCA_Melms

[Elham Azizi @elhamazizi]

Our first (of many to come😃) exciting collaborative effort(s) with the @BizarMd Lab, led by superstars Yiping Wang @joy_lfan @JCA_Melms bringing multimodal single-nucleus RNA/TCR, spatial and whole-genome seq to the #clinical arena!
#cancergenomics #computationalbiology