Jonathan Smith

infectious disease epidemiologist

[Jonathan Smith @jpsmithuga]

Our recent work examining the impact of #PEPFAR on the global #TB epidemic - published today in @NEJM

https://t.co/D3mjmJ0UsI

[NEJM @NEJM]

Tuberculosis remains a leading cause of death worldwide among persons with HIV. In this report, the effect of the PEPFAR program on incident cases of tuberculosis and related deaths is presented. Read the full report: https://t.co/qmpnYA45W7

@CDCgov | #WorldTBDay

[Jonathan Smith @jpsmithuga]

Lab-confirmed #TB diagnoses in young kids often require invasive procedures that cause severe physical and mental distress. In @PLOSDigiHealth we show #MachineLearning can help clinicians decide if these costly, invasive procedures should be ordered #EndTB https://t.co/oB8GYwkr3h

[Jonathan Smith @jpsmithuga]

In this @CDCMMWR, we demonstrate a collection of interventions improved #MDR #TB treatment retention among highly mobile migrant patients during the #COVID19 in India. It will take a lot of hard work, but #YesWeCanEndTB #WorldTBDay #EndTB https://t.co/mS2oD2Ioms

[Emory/Georgia TB Research Advancement Center-TRAC @Emory_TB_Center]

Thank you Dean Fallin of @EmoryRollins and Dr. Lash of @EmoryEPI for stopping by to support the TRAC before World TB Day @DeanDaniFallin @neelrgandhi

[Jonathan Smith @jpsmithuga]

Our study on isolation and quarantine behaviors in the US during the #COVID19 pandemic found that most infected individuals chose to isolate. Contact tracing helped, but the proportion of adults engaging with the public health system was suboptimal https://t.co/CFOIUfOEEZ

[Jonathan Smith @jpsmithuga]

Congrats to @kennyguna and team for spearheading important work in guiding sensible and clinically appropriate decision making in pediatric #TB - one of the leading causes of death for children worldwide. An enormous step forward to #EndTB https://t.co/SdfmkDoY5D

[Jonathan Smith @jpsmithuga]

We used whole genome sequencing from a population-based cohort and 2 decades of clinical encounter data to identify nosocomial transmission of #tuberculosis in Botswana: odds were over 6x in rural vs urban facilities. Read more @AmJEpi #EndTB #StopTB #TB https://t.co/edyWegbYrX

[CDC Advanced Molecular Detection @CDC_AMD]

In a recent study, scientists searched for population-based analysis in which #WGS was used to estimate #TB transmission and clusters. Identifying geographic sources may have a considerable impact on controlling and mitigating TB transmission.
https://t.co/IqTzHjnVGp

[SER Publications @epipubs]

New in @AmJEpi - @jpsmithuga @ted_h_cohen @davidwdowdy @soustha @neelrgandhi and Hill offer a systematic analysis quantifying tuberculosis transmission dynamics from 8 global settings @societyforepi. Check it out here ➡️ https://t.co/eUELQyHcd6

[Open Forum Infectious Diseases @OFIDJournal]

Clinical and radiologic factors associated with detection of Mycobacterium tuberculosis in children under 5 years old using invasive and noninvasive sample collection techniques - Kenya

✅ Just Accepted
🔓 Open Access
🔗 https://t.co/jYGmf2EVmE

[Jonathan Smith @jpsmithuga]

@BryanDJames Hi @BryanDJames - thanks! I uploaded the reproducible code I used to create this GIF on GitHub for you: https://t.co/csQ4YmQVCF Basically made 1000 pngs and stitched them together. Hope you have a great day!

[Jonathan Smith @jpsmithuga]

Diagnosing kids with #TB is among the greatest ongoing challenges to #EndTB - 96% of kids who die of TB are undiagnosed. Here, we examine clinical/CXR factors associated w/ lab-confirmed TB in young kids across multiple sample techniques @OFIDJournal #tb https://t.co/ztjD5fU2Lk

[Am J Epidemiology @AmJEpi]

New in AJE:

Interested in #TB transmission dynamics? This systematic analysis of whole genome sequencing data estimates that 80% of TB transmission occurs from less than 30% of cases
@jpsmithuga @neelrgandhi @ted_h_cohen @soustha @davidwdowdy

https://t.co/by8JE5BGZG

[Jonathan Smith @jpsmithuga]

Interested in #TB transmission dynamics? Our new systematic analysis quantifying #TB transmission is out in @AmJEpi - we found most TB is spread by a minority of cases across global settings @davidwdowdy @neelrgandhi @ted_h_cohen @soustha @Emory_TB_Center https://t.co/s2OjxVka11

[Emory/Georgia TB Research Advancement Center-TRAC @Emory_TB_Center]

New systematic analysis in @AmJEpi using whole genome sequencing to identify #TB transmission clusters suggests 2-31% of cases drive >80% of TB transmission across global settings. @jpsmithuga @ted_h_cohen @soustha @davidwdowdy @neelrgandhi https://t.co/2Qn4CAtRR1”

[Jonathan Smith @jpsmithuga]

Understanding TB transmission dynamics in high-burden settings is notoriously challenging. Here we use geospatial, genotypic, & clinical data of #TB cases in Botswana and find transmission dynamics vary markedly between high-burden subpopulations #endTB https://t.co/LhjXWFWuS4

[CDC Global Health @CDCGlobal]

A recent CDC study of tuberculosis (TB) transmission in Botswana shows little risk from healthcare settings and highlights the need for targeted interventions aimed at community spread of #TB. Learn more about the findings: https://t.co/NnbtxaCRCj

[Jonathan Smith @jpsmithuga]

Healthcare facilities are high-risk for TB transmission, but how do they contribute to the overall TB epidemic? We combined detailed cohort and 2 decades of clinical encounter data to find ~5% of all TB transmission is attributed to HCFs in Botswana @iche https://t.co/eZIreSCvAd