Welcome GeNetRank ! it goes well with fate-seq to prioritize the molecular factors regulating cell response dynamics and drug mechanisms of action.
@PLOSONE: Gene prioritization based on random walks with restarts and absorbing states, ...
https://t.co/aLnzafHNOE
We also just shared our protocol for fate-seq @STARProtocols to isolate drug-tolerant cells in their transient state of sensitivity, right before profiling
Coupling live-cell imaging and in situ isolation of the same single-cell ...
https://t.co/O3CGfA7zQ6
Very happy to share our new paper made in @Univ_CotedAzur, @ircaninstitute, @inria_sophia ...
Two-level modeling approach to identify the regulatory dynamics capturing drug response heterogeneity in single cells, @SciReports
https://t.co/wXFRakULGa
We utilize single-cell dynamics to identify regulatory reactions that drive response heterogeneity in clonal cells. Heterogeneity-driving reactions can then be used to augment the initial model with a mechanism that leads to drug response variability of non-genetic origins.
Our follow up paper on unwanted on-target side effects in germline genome editing is out. Big thanks to Rudolf Jaenisch lab for this exciting collaboration https://t.co/xHCeBb6uvI
50 membres du collectif #TerraNumerica se sont réunis hier pour la 1ère AG 2021.
Messages d'ouverture des directions d'@Inria_sophia, @DR_20 et @Univ_CotedAzur et annonce d'un espace de 500 m2 mis à dispo par @ValbonneSA
Les projets 2021 ? C'est sur https://t.co/TmMlK3tYRW
Envie de découvrir, explorer et expérimenter les sciences du numériques ? Suivez-nous et embarquez pour #TerraNumerica, un projet azuréen porté par @CNRS_DR20 @inria_sophia et @Univ_CotedAzur regroupant un bel ensemble de partenaires dont @education_gouv
Happy to see our recent work on melanoma persister cells highlighted, together with other fascinating studies, in this very interesting article from Le Monde - Science & Medicine. "Cancer: faced with the threat of persistent cells, the creativity of researchers as the antidote".
Le Monde, Cancer: la recherche axée sur l’origine non-génétique de la résistance thérapeutique. Notre approche @CellSystemsCP (@Univ_CotedAzur, @CNRS_DR20, @ircaninstitute) est citée avec les travaux de nombreux spécialistes du sujet @sorger_peter, ...
Happy to launch the Human Protein Atlas Single Cell Classification Challenge w @kaggle @humanproteome today! Help us develop models for classification of protein patterns in single cells in microcopy images. Please RT 🙏
#ImageClassification#ML#CellAtlas https://t.co/l4bH8sZD2Q
Maybe a controversial opinion: most new techniques in science just generate huge lists, which is easy. Much harder is to MAKE SENSE of those lists...but that work is not being rewarded or funded! Let's take gene ontology as an example, the lists are often organized this way...