Jim Spellos

It's all about the way cool tools and the healthy whole food, plant-based lifestyle.

[Louis Gleeson @aigleeson]

🚨 BREAKING: The most important Claude plugin in existence just dropped on GitHub and nobody is talking about it.

It's called claude-scientific-skills.

140 scientific skills across every major research domain baked into one plugin.

Install it once. Claude becomes a full AI research scientist permanently.

Here's what it can run from a single prompt:

→ Full drug discovery pipelines with real bioactive compound queries
→ Single-cell RNA sequencing analysis with Scanpy
→ Clinical variant annotation with ClinVar and Ensembl
→ Molecular docking against AlphaFold structures via DiffDock
→ Patient to trial matching via live ClinicalTrials. gov data
→ Publication-ready PDF clinical reports generated automatically

Bioinformatics. Cheminformatics. Proteomics. Quantum computing. Medical imaging. Laboratory automation.

All connected to the databases and tools scientists actually use.

One prompt. Real science. Actual results.

This is not a chatbot anymore.

/plugin install scientific-skills@claude-scientific-skills

100% Open Source. MIT License.

Link in the comments.

[Jim Spellos @jspellos]

For those diving into this service, read Karpathy's intelligent review first

[Andrej Karpathy @karpathy]

I'm being accused of overhyping the [site everyone heard too much about today already]. People's reactions varied very widely, from "how is this interesting at all" all the way to "it's so over".

To add a few words beyond just memes in jest - obviously when you take a look at the activity, it's a lot of garbage - spams, scams, slop, the crypto people, highly concerning privacy/security prompt injection attacks wild west, and a lot of it is explicitly prompted and fake posts/comments designed to convert attention into ad revenue sharing. And this is clearly not the first the LLMs were put in a loop to talk to each other. So yes it's a dumpster fire and I also definitely do not recommend that people run this stuff on their computers (I ran mine in an isolated computing environment and even then I was scared), it's way too much of a wild west and you are putting your computer and private data at a high risk.

That said - we have never seen this many LLM agents (150,000 atm!) wired up via a global, persistent, agent-first scratchpad. Each of these agents is fairly individually quite capable now, they have their own unique context, data, knowledge, tools, instructions, and the network of all that at this scale is simply unprecedented.

This brings me again to a tweet from a few days ago
"The majority of the ruff ruff is people who look at the current point and people who look at the current slope.", which imo again gets to the heart of the variance. Yes clearly it's a dumpster fire right now. But it's also true that we are well into uncharted territory with bleeding edge automations that we barely even understand individually, let alone a network there of reaching in numbers possibly into ~millions. With increasing capability and increasing proliferation, the second order effects of agent networks that share scratchpads are very difficult to anticipate. I don't really know that we are getting a coordinated "skynet" (thought it clearly type checks as early stages of a lot of AI takeoff scifi, the toddler version), but certainly what we are getting is a complete mess of a computer security nightmare at scale. We may also see all kinds of weird activity, e.g. viruses of text that spread across agents, a lot more gain of function on jailbreaks, weird attractor states, highly correlated botnet-like activity, delusions/ psychosis both agent and human, etc. It's very hard to tell, the experiment is running live.

TLDR sure maybe I am "overhyping" what you see today, but I am not overhyping large networks of autonomous LLM agents in principle, that I'm pretty sure.

[Jim Spellos @jspellos]

AI browsing is (nearly) here. https://t.co/EiR0E7pTxZ

[NCS4 @NCS4usm]

Step into the dynamic world of Generative AI as James Spellos, President, Meeting U., leads a hands-on workshop designed to elevate your understanding and practical skills.

https://t.co/cjDVT1pYHD

[Jim Spellos @jspellos]

Why? Because AI Said So. https://t.co/YhfjN5ur9J

[Jim Spellos @jspellos]

A fascinating read: https://t.co/V9Rp4KSFCS

[Aravind Srinivas @AravSrinivas]

We've shipped many things in Perplexity, but integrating DeepSeek R1 with search is truly a phenomenal experience, seeing the model think out loud like an intelligent person, reading hundreds of sources, with sleek UX. Yes, the limits suck right now, but as I promised, we will increase them every day.

[Jim Spellos @jspellos]

So worth sharing.

[Yann LeCun @ylecun]

Worth repeating:
Do not confuse retrieval with reasoning.
Do not confuse rote learning with understanding.
Do not confuse accumulated knowledge with intelligence.

[Mishaal Rahman @MishaalRahman]

You can now send a video to Google to ask questions about it!

If you open Google Lens on Android and hold down the shutter button, it'll record a short video that you can ask a question about.

If you're in a region where AI overviews are enabled, then you'll get an AI-generated response to your question.

Google announced this feature back at I/O in May but it's started to roll out for some users in the last few days. LMK if you have it!

[Jim Spellos @jspellos]

@meetingstoday @MsAliciaJenelle So honored. Thanks @meetingstoday

[Matt Wolfe @mreflow]

Rounding up the AI news from this week. It was actually a pretty massive week (again).

Here's what I've got so far...
- Grok 2 is released with Flux.1 image generation
- Anthropic rolls out Prompt Caching in the API
- A new version of GPT-4o rolled out in ChatGPT
- A new version of GPT-4o tops the LMSYS Leaderboard
- OpenAI releases new software engineering benchmark
- Google shows off "Gemini Live" - Google's new voice assistant
- Google uses AI to add more accessibility features to new Pixel phones
- Google's Pixel Buds are designed for Gemini Live
- Google updates the AI Overview search feature
- Runway's Gen-3 Alpha Turbo is now available
- Copyright lawsuit against MidJourney and Stability allowed to proceed
- SAG-AFTRA Strike AI deal with Narrativ to get voice actors paid

It wasn't one of those AI news weeks where a million things happened but it was a week where a few BIG things happened.

I know I missed some things. Please let me know what I missed. Reply with announcements, launch news, etc. that I might have overlooked this week. :)

[Jim Spellos @jspellos]

For my Patreon subscribers, check out Wondercraft AI podcast creator. https://t.co/cE1mLNNHtp

[Jim Spellos @jspellos]

AI podcast creation tool - @wondercraft_ai . Pretty cool stuff. Here's one I just created, for an AI review in 2 minutes https://t.co/onQdxF4633

[Brad Stulberg @BStulberg]

I am always shocked at the number of bizarre things people do to "optimize" their health and longevity and yet they don't exercise regularly, sleep 7-9 hours, eat fruits and veggies, build intimate bonds and community, or ever relax.

They obsess over the 0.1% but not the 99.9%.

[Jim Spellos @jspellos]

Fan of @perplexity_ai ? You should be, and you should check out their newest feature, Pages. https://t.co/GtpmON7qg3

[Jim Spellos @jspellos]

While OpenAI fights, Claude grows. https://t.co/4ohm2fWPzL

[Jim Spellos @jspellos]

How to use text to Video for your social posts: https://t.co/Dyuqgp5Ihz

[Jim Spellos @jspellos]

Everything AI Handout - exclusive to my Patreon followers. https://t.co/RMH9iaLEAi

[Jim Spellos @jspellos]

Welcoming @attendeenet as a sponsor to my Everything AI webinar. https://t.co/DxGTRHiPN3