Happy to share our SPOTLIGHT piece in @AACR describing distinct mechanisms of resistance to the different CDK4/6 inhibitors. As such, patients who progress on each of the CDK4/6 inhibitors may respond to different types of subsequent therapies. https://t.co/Slo5VaeLTS
Our novel finding on distinct mechanisms of resistance to palbociclib and abemaciclib in HR+ / HER2- MBC. Is there rationale for switching CDK4/6i after progression? @kandymarsy@KellyKhunt@MDAndersonNews@CR_AACR@HarmonyTurk https://t.co/BMmXIlJ3kt