Hot out of the PRESS: ExPRESSO☕️🗜️: Physical expansion of FFPE tissues (or cells) for spatial proteomics!
It works under VACUUM‼️: extending hydrogels to mass spectrometry imaging!
Amazing work of the new Dr. Yunhao Bai, with Bokai, @xavi_r_c , and the bossman @GarryPNolan
Single-cell mass cytometry of high grade gliomas and brain metastases shows spatial neighborhoods and a population of MPO-positive macrophages associated with long-term survival in patients #NBThighlight https://t.co/ZtTb4J5WJp
The tonsils and adenoids of children who have had Covid have persistent tissue-specific immunity which includes antigen-specific memory B and T cells
https://t.co/fxTpLKz1oU @NatImmunol by @ManthiramMD and colleagues @NIAIDNews
A new algorithm shows promising accuracy in detecting the normal or abnormal numbers of chromosomes in IVF embryos, according to a team of Weill Cornell Medicine researchers.
https://t.co/tzhBS6E74g
Exciting times in omics! In our new @GenomeBiology paper, "Spatial omics technologies at multimodal and single cell/subcellular level," we detail the wide range of technologies, including some that can now get down to 50nm resolution, led by @JIWOONPARK_ https://t.co/XBNA7y1kFy
Out yesterday from @marius10p and @computingnature: Cellpose 2.0 offers pretrained models and human-in-the-loop training for improved segmentation with fewer user annotated regions.
OA paper: https://t.co/tkLSVAcNnk
Using new computational method, scientists map tissue structure in unprecedented detail.
Findings could improve understanding of cell activity and healthy and diseased
organ function, says Dr. Oliver Elemento (@ElementoLab) of @WCMEnglanderIPM.
https://t.co/6bKA1VjbYn
Out today from the Rendeiro and Elemento labs comes Unsupervised discovery of Tissue Architecture with Graphs (UTAG) to identify architectural domains from highly multiplexed tissue imaging data! https://t.co/ddiWNT1EZ6
Happy to share that my first first author paper is publicly available! Special thanks to @afrendeiro and @ElementoLab for advising the work!
https://t.co/EqmqwbiuiH
@naturemethods
Are you using multiplex single-cell imaging to study healthy or disease tissue? if so check out this great new computational technique to analyze tissue architecture, uncover cellular domains and the many new insights that followed. Great work led by @junbum_kim and @afrendeiro !