What a night and inspiring community! Fantastic to celebrate the 2nd year and all the accomplishments of the Women in TPD & Induced Proximity Initiative ☺️ Thank you @foghorntx for hosting us
Thrilled that our Epigenetic Drug Discovery book chapter on targeting chromatin remodeling complexes is finally out! Thank you to my colleagues @foghorntx for their contributions and Ho Man Chan and @CherylArrowsmi1 for editing the entire book.
https://t.co/fgVgPKkso4
Interesting talk by Samantha Bevill @DFCI_ChemBio at #TPDWebinar. She talked about her research into developing tumor-specific PROTACs on the example of engaging the E3 ubiquitin ligase MDM2 to specifically degrade proteins in MDM2-amplified cancer cells. https://t.co/0BuSaL9UOD
We're pleased to announce that our BRM selective inhibitor, in partnership with Lilly, is moving into the clinic. Learn more about the news and our primary development plans to target BRG1 mutated non-small cell lung #cancer (NSCLC): https://t.co/Dfrc9dRG9W
What a structure! A first glimpse of complete PROTAC ternary complexes between the CUL2-VHL complex and BRD4 to understand productive ubiquitination. Congratulations to first author @CharlCrowe and colleagues @UoDCeTPD Dundee on this breakthrough!
https://t.co/SLesTMxsnt
We celebrated the beginning of 2024 by coming together as a team for an evening filled with food, games and fun! Check out pictures from our annual holiday party. #LifeAtFoghorn#biotechcareers
Meet Alexia Kalogeropulou, one of our brilliant scientists at Foghorn. Alexia shares why she loves the collaborative culture that enables us to advance our mission to transform the lives of people living with a wide spectrum of diseases. #LifeAtFoghorn#WomenInSTEM#biotechnology
Exciting times for #TPD - this Wednesday, @CraigMCrews and Raymond Deshaies will receive the 25th Gabbay Award for advancing biotechnology and medicine. The lecture hosted by @BrandeisScience is open and free for everyone (and @BrandeisU campus is lovely and worth the trip).
We recently published an article in
@CellCellPress to highlight the recent exciting discoveries around UBR5 & propose applications for modulating this E3 ligase to drive targeted #proteindegradation of key transcriptional targets implicated in disease: https://t.co/PP5GpqGd9f
On Wednesday, Foghorn Senior Scientist Karolina Mizeracka will present a poster at the Targeted Protein Degradation Symposium on our selective CPB and selective EP300 programs, which have the potential to address over 100,000 patients per year across many indications. #oncology
Hello - what is this cute couple up to?
Here we have two adult C. elegans nematodes. The animals shaded in blue and red are opposite sexes. Can you find the difference?
Our next TPD webinar is only two days away! Join us Thursday for two great talks from Anthony Partridge and Steven Bellon, PhD! Register at https://t.co/XtCAtBYXBI #webinar#tpd https://t.co/KvS99R28Nn