@SyedYNaqvi1 We just finished our RCT with pre-procedural 3D-CT versus angio guided PCI to determine the optimal C-arm angle for ostial RCA lesions (n=30). Primary end-point coverage of the ostium by IVUS. Results will be out soon!
@FH_Verbrugge@EHJACVCEiC Great work! Provocative question: should coronary anatomy be a variable in the decision to use vasodilators? Being a big fan of nitroprusside, I am a little more hesitant in patients with severe 3VD or unknown anatomy since DBP ⬇️ could ⬇️ coronary perfusion and ⬇️ CO…
@JohannesGrand@thiele_holger@escardio@AGIKinterv@AnneFreund3@krychtiukmd@PabloJ I think it may be due to the combination of (1) inadequate ventilation in the cathlab with hypo/hyperoxemia & hypo/hypercapnia (2) MAP fluctuations during the cath procedure and (3) missed diagnoses such as PE or ICB in these patients without ST elevation
@nolanjimradial@evandrofilhobr We are currently randomizing patients in the RADVES trial between Terumo and Silverway after the standard J-tip wire had failed to cross (NCT05231889). Results expected end Q2…
@ElevenSportsBEn @Jupiler Wat vinden jullie bij @ElevenSportsBEn van een commentator die vindt dat Onuachu ‘op zijn poten moet blijven staan’? Beetje niveau aub…
@LiorBibasMD@JACCJournals Thnx! Agree that cMRI would have been a better estimate of AMI size! However, cMRI Would probably not be feasible at day 5-10 in many shock patients (35% of our cohort would already be death by that time)
Targeting a mean arterial pressure between 80/85 and 100 mmHg in post-arrest #cvMI patients in shock is associated with smaller myocardial injury. Learn more in #JACC: https://t.co/A2OXN2OGhK
@pedschwartzmann@FH_Verbrugge@JACCJournals In our forest plot, results were mainly driven by differences obtained in STEMI patients with TIMI 0 flow in the LAD.. seems like patients with the largest AMI might benefit most..
@pedschwartzmann@FH_Verbrugge@JACCJournals There are obviously no data at all to support a 65mmHg target.. I think there are some similarities between stroke (penumbra/core) and STEMI and that you should consider giving NE even in patients with MAP 65 and normal lactate/diuresis/brain to salvage the cardiac penumbra..
@drozant1@FH_Verbrugge@JACCJournals Unfortunately, at least in our series rates of RRT are very low.. analysis will be underpowered for this.. however, data on creatinin and diuresis will be interesting!
@DrLbatt@Mosaad The assocation between earlier start of vasopressors and worse outcome in previous observational studies is probably just biased by patients with deeper shock getting earlier vasoactive drugs
@DrLbatt@Mosaad Unfortunately, it is impossible to say how our 37% reduction in AUC cTnT Would correspond with reduction of infarct size on cMRI.. however, don’t forget that each 5% reduction of infarct size is theoretically associated with a 20% reduction of death and HF hospitalizations..
@drozant1@FH_Verbrugge@JACCJournals We are currently working on a pooled analysis of both trials on GFR and diuresis! Will Hopefully be published Q4 2020..