NBRC’s Karthick Ravichandran elegantly tied together the sub-cellular, metabolic & cognitive effects of tiredness in mice - highlighting the transcriptional and translational control of mitochondrial activity upon sleep deprivation.
#EMBOneuroSleep https://t.co/tLdlIrBBcO
A commercially available plasma p-tau217 immunoassay accurately identified biological AD, comparable with results using CSF biomarkers, with reproducible cut-offs across cohorts. It detected longitudinal changes, including at the preclinical stage.
https://t.co/EXJDvPc9bU
I need to acknowledge our director of grad studies @GregoryRSL for treating all students—current, past, accepted, & rejected—with the kindness that academia can so sadly lack. He’s going viral on Reddit for his thoughtful rejection letters, & I hope other programs follow suit.
We are thrilled to share a new study from the lab on the neural mechanism of helping behavior. Humans and animals exhibit helping behavior toward others in need. In this study, we report an intriguing form of helping behavior that an individual exhibits toward others experiencing pain, and uncover the role of the anterior cingulate cortex in encoding and controlling this behavior. @Nature https://t.co/w4z06dy9jT
New study suggests time-restricted feeding may ameliorate Alzheimer's by resetting the circadian clock & increasing repair via mTOR & SIRT1🐁 Free link: @Cell_Metabolism https://t.co/BttatDv931
A person with Parkinson's disease can't walk because of severe freezing but put him on a bike and he is fine. Great case by Snijders and @basbloem Love the explanation: 'This striking kinesia paradoxica may be explained by the bicycle's rotating pedals, which may act as an external pacing cue. Alternatively, the motor-control mechanisms involved in gait as compared with other activities engaging the legs, such as cycling, could be affected differentially in Parkinson's disease. Cycling may offer a useful approach for exercise training in patients with Parkinson's who are “grounded” by severe freezing of gait.' https://t.co/fq5oe2oodu https://t.co/fq3jiDgUBC
“Ten years ago I was kicked out and forced to retire.”
Our new medicine laureate Katalin Karikó (@kkariko) told us how much it means to be awarded the Nobel Prize after a scientific career that has been full of challenges.
Ten years ago, Karikó was still doing all her experiments by hand but today she has been awarded the medicine prize for her research on mRNA, which led to the development of COVID-19 vaccines.
Listen now:
@PhDVoice@Academic_Tasks@PostdocVoice Here is a great piece of paper written by my advisor on effective graduate mentoring. The best line for me from the paper is “most important is for the graduate mentor to buy into the success and well-being of the student”.
Give it a read
https://t.co/nSmP2PaxFj
Colleagues and fellow researchers,
Our community must be aware of these red flags, as they hinder our research's progress and quality and impact the mental and emotional well-being of our brightest minds.
See the full post in my newsletter: https://t.co/bRkSlJdzjj
#LabCulture #ResearchIntegrity #HealthyWorkplace #ScienceMatters
#Always available
#AIIMSParivar
While returning from ISVIR- on board Bangalore to Delhi flight today evening, in Vistara Airline flight UK-814- A distress call was announced
It was a 2 year old cyanotic female child who was operated outside for intracardiac repair , was unconscious and cyanosed
5 Doctors from @aiims_newdelhi were onboard
Dr Navdeep Kaur- SR Anesthesia
Dr Damandeep Singh- SR Cardiac Radiology
Dr Rishab Jain- Ex SR AIIMS Radiology
Dr Oishika- SR OBG
Dr Avichala Taxak- SR Cardiac Radiology
Immediately child was examined - his pulse was absent, extremities were cold , child was not breathing with cyanosed lips and fingers
On air- Immediate CPR was started and with limited resources, using skilled work and active management by team
Successfully IV canulla was placed , oropharyngeal airway was put and emergency response was initiated by whole team of residents on board- and the baby for brought to ROSC- return of circulation.
It was complicated by another cardiac arrest for which an AED was used.
For 45 mins , baby was resuscitated and flight was routed to Nagpur
On reaching Nagpur, child was handed over in stable hemodynamic to the pediatrician
Our new study is out today in Nature! We demonstrate a brain-computer interface that turns speech-related neural activity into text, enabling a person with paralysis to communicate at 62 words per minute - 3.4 times faster than prior work. 1/3 https://t.co/6pB7NLAqjG
Want to sequence RNA from cells without killing them or deliver RNA programs from cell to cell? Today in Cell, we present RNA exporters, which package and secrete cellular RNA, for non-destructively monitoring cell dynamics by sequencing and delivering RNA https://t.co/JG1mzYvLgb