Katpjotr

[Zdenek Vrozina @ZdenekVrozina]

GP visits for memory problems in Norway have more than doubled since 2019 - 41,722 to 98,910. And the steepest rise isn't in the elderly. It's in children aged 5 to 14, where they've nearly tripled🧵

[Katpjotr @katpjotr]

@MoreBirths Sure that your numbers are correct? China reports less births than the number cited... https://t.co/tVZzx1KGh5

[Thomas Dayspring @Drlipid]

In view of all the Lp(a) interest, I thought it is a good timed to again explain and make less confusing Lp(a) and LDL metrics using my graphics. There is tremendous misuse of various particle metrics. Once again - LDL refers to a specific lipoprotein - THERE IS NO LAB TEST CALLLED LDL, Enlarge the graphic to study the subtleties. @nationallipid @foundationofnla @society_eas @ASPCardio @escardio @atherosociety @TheEndoSociety @FamilyHeartFdn @fhpatienteurope #cholesterol

[Eric Topol @EricTopol]

Why did 2 large, pivotal clinical trials [vs interleukin-6 and Lp(a)] fail to lower heart attacks, strokes and cardiovascular deaths?
In the new Ground Truths (link in profile)

[Harry Spoelstra @HarrySpoelstra]

Belgium SARSCOV2 Wastewater surveillance update:

‼️CAUTION, after nearly 5 months of low detection levels, STARK National increase appears!!

These are carried by:
- Stations Bruges and Aalst(stark increases → HIGH ACTIVITY LEVEL), and
-Widespread hints of possible SARSCOV2 detection increases, especially in Brussels.

😷Something to follow!

- Just as a reminder: NO Influenza and RSV detection!
- Summer school holidays end today in Wallonia, next week in Flanders
- Belgium has ZERO genomic surveillance!
#AvoidSars2 #AvoidReinfections
https://t.co/YWlFl8YCts

[Manuel Ruiz @manruipa]

🔴 What if EBV is not simply “reactivating” after COVID?

What if, in some people, it is changing the behaviour of the B cells it inhabits?

A new 2026 preprint reports something fascinating:

EBV+ B cells in people with COVID show an autoimmune-like, metabolically reprogrammed state.

And this connects with a much larger story involving:
EBV
B cells
HLA
failed immune control
persistent antigen
and autoimmunity.

Let’s go through it.

(1/64) 🧵

[Harry Spoelstra @HarrySpoelstra]

Debunking the "COVID was just like the flu with 0.1-0.2% IFR" claim!

😡You’ve seen the posts: “COVID IFR was only 0.1–0.2%, same as seasonal flu!” spread by some epidemiologists and others with clear minimalization narratives, often financially driven!

➡️Disinformation and CLEARLY not what the actual 2020 pre-vaccine data showed, bear with me:

➡️The reality by age (2020, pre-vaccines)
Here’s the clear comparison from major seroprevalence meta-analyses (Levin, O’Driscoll, IHME) for COVID infection fatality rates versus typical seasonal influenza symptomatic case-fatality rates:
Look at the pattern:
- Kids and young adults: both very low,
- From the 40s–50s onward: COVID was several times higher,
- In the 60s–80s+: COVID IFR was often 5–10× (or more) that of flu,

➡️Overall “0.1–0.2%” numbers only appear if you average across a very young population or cherry-pick the lowest possible estimates while ignoring age structure,
In high-income countries with normal age pyramids, 2020 COVID overall IFR was typically estimated in the 0.5–1%+ range, driven hard by the elderly and middle-aged,

➡️And the scale of infections was not “just a bad flu season,”
In the US alone by the end of 2020:

⭐~103 million estimated COVID infections
vs
⭐~35 million symptomatic flu illnesses in the entire 2019–2020 season,

Three times the infections + substantially higher fatality risk once infected (especially after age 50) = the excess deaths and hospital overload we actually saw,

➡️Six years later, SARSCoV2 is still circulating globally. WHO rates the ongoing public-health risk as moderate(!). Confirmed cases exceed 779 million and deaths exceed 7 million, while seroprevalence data show even orders of magnitude of infections and reinfections much higher. SarsCoV2 continues it’s cunning mutational survival battle, with thanks to our “let it rip” policies. Breakthrough infections subsequently continue even in vaccinated people today (vaccines still cut severe outcomes roughly in half, but do not stop transmission),

And then we have LongC0VID, that also still affects an important and probably growing share of those infected. Global estimates put it around 6-10% of (a)symptomatic cases, with a substantial fraction remaining symptomatic at 12 months, and some studies finding cumulative rates of 1 in 6. Millions, yes, millions live with these, often lasting and debilitating symptoms,

COVID was never “just the flu,”

The 2020 data already proved the higher age-specific IFR and vastly greater infection volume,

The fact that it is still causing breakthroughs, reinfections, and LongC0VID in 2026 only underscores my point, and should be taken seriously, as I’M HONESTLY CONCENERED WITH YOUR HEALTH!
#AvoidSars2 #AvoidReinfections

[Katpjotr @katpjotr]

@deNutrients @Elifbenad This is shiitake dermatitis, a well know issue in toxicology.

[Anirban Maitra @Aiims1742]

Congratulations to the @RevMedicines & @break_cancer KRAS team for this collaboration in @NatureMedicine:

Acquired resistance to the RAS(ON) multi-selective inhibitor daraxonrasib guides rational combination therapy strategies in #PancreaticCancer
https://t.co/ohZhC1Jk7P

[Harry Spoelstra @HarrySpoelstra]

Patterns and trends of mortality in patients with arrhythmia and cerebrovascular disease in the United States: a nationwide analysis of older adults

🚨REMINDER: One graph tells you more than a thousand words → COVID-19 is a CV threat!

➡️Fig. 1 of this new Scientific Report shows 25 years of arrhythmia + cerebrovascular mortality rates in US adults ≥65.

➡️The line stays almost flat… until 2018–2021, when it rockets upward (AAMR 65.51 → 80.44).

➡️That steep climb sits directly in the COVID-19 years, and the authors themselves admit and link it to the pandemic-era reversal in cardiovascular death decline.
#AvoidSars2 #AvoidReinfections
For further details👇
https://t.co/zhYaVhLgl9

[Piers Morgan @piersmorgan]

Disgusting behaviour by the Argentinians at the end, especially Paredes.
Just a bunch of nasty violent thugs, and a disgrace to football. Never been so happy to see a team lose.

[Adam Schwarz @AdamJSchwarz]

Leandro Paredes should be banned from international football for life viciously assaulting Spanish players after the final whistle.

Indefensible thuggery and criminality.

[Anton Gerashchenko @Gerashchenko_en]

In my opinion, Mykhailo Fedorov was the best defense minister. He was highly effective and efficient, talented, systemic, with out-of-the-box solutions, an effective and productive team. During his very short time on this position, Mykhailo accomplished so much for Ukraine's defense and our victory.

Thank you, @FedorovMykhailo.
I'm certain that you will continue working for Ukrainian resilience.

[Katpjotr @katpjotr]

@serenityposting @JeanDarc815 @Babygravy9 The measure offers one-year residence and work permits to unauthorized migrants present in Spain before January 1, 2026. If they are not naturalized, they obtain no EU citizenship.

[Katpjotr @katpjotr]

@serenityposting @JeanDarc815 @Babygravy9 That will not be a problem in Spain as they speak the same language.

[Katpjotr @katpjotr]

@james_jimm96174 @JeanDarc815 @Babygravy9 Check your sources: 84% have full proficiency in Spanish. https://t.co/778yPtUn2b?

[Katpjotr @katpjotr]

@JeanDarc815 @Babygravy9 These are spanish-speaking people from former colonies. Why would they go to Germany or France?

[Dr Jérôme BARRIERE, MD. @barriere_dr]

Alors voici ma réponse à @laliguecancer si ça intéresse @franceinfo

La Ligue contre le cancer a toute légitimité à défendre la prévention.

Mais elle semble, depuis quelque temps, adopter des positions militantes qui l’éloignent de la nécessaire rigueur scientifique attendue d’une institution portant le mot « #cancer ».

Le débat sur l’#acétamipride en a fourni une illustration particulièrement préoccupante et l’interview rapportée de son président en est ici l’illustration parfaite.

En juillet 2025, la Ligue affirmait que cette molécule était, « d’après des études récentes, potentiellement cancérigène » (cf capture), avant de citer l’expertise collective de l’Inserm établissant des liens entre certaines expositions professionnelles à certains pesticides et plusieurs cancers.

https://t.co/3IuwQxkeOe

Or cette expertise ne démontre absolument pas que l’acétamipride serait responsable de ces cancers.

Passer des pesticides en général à une molécule particulière constitue une extrapolation scientifiquement injustifiée.

Et c’est GRAVE !

À ce jour, aucune donnée épidémiologique robuste ne met en évidence un sur-risque de cancer chez l’être humain attribuable à l’acétamipride, encore moins aux niveaux d’exposition alimentaire observés dans la population.

S’en servir ici pour appuyer un plaidoyer pour inscrire dans la Constitution un principe de précaution sanitaire est donc bel et bien une dérive militante.

Car par exemple, comme toujours dans ce type de débat, les quantités disparaissent ainsi que la ≠ entre danger théorique et risque réel.

On l’a vu hier : des analyses médiatisées dans Le Monde ont ainsi trouvé jusqu’à 4 980 nanogrammes d’acétamipride par kilogramme de miel, soit 0,00498 milligramme par kilogramme.

Le chiffre paraît impressionnant lorsqu’il est exprimé en nanogrammes.

Mais l’EFSA a fixé, en intégrant une importante marge de sécurité, une dose journalière admissible de 0,005 mg par kilogramme de poids corporel et par jour

À cette concentration, un adulte de 70 kg devrait consommer environ 70 kg de ce miel chaque jour pour atteindre cette dose journalière admissible par ce seul aliment ! Même un enfant de 20 kg devrait en consommer environ 20 kg par jour !!

Et atteindre la dose journalière admissible ne signifie toujours pas atteindre une dose toxique : il s’agit précisément d’un niveau réglementaire construit pour pouvoir être consommé quotidiennement toute une vie sans risque appréciable.

C’est toute la différence entre :

détecter une molécule ;
identifier un danger dans certaines conditions expérimentales ;
démontrer un risque réel aux doses auxquelles la population est exposée ;
et constater une augmentation de cancers (ou autre maladie) chez l’être humain.

Ces quatre étapes sont régulièrement confondues dans le débat public.

L’exemple de l’acétamipride montre ainsi le danger d’un principe constitutionnel de précaution sanitaire formulé de façon trop générale. Il suffirait de détecter une substance, d’obtenir un résultat expérimental à forte dose ou de publier une association observationnelle fragile pour demander l’interdiction d’une politique publique.

Le principe de précaution deviendrait alors un principe de la peur ou de l’inaction : une hypothèse non quantifiée pèserait davantage que l’évaluation comparative des risques, des bénéfices, des solutions de remplacement et des conséquences économiques ou sanitaires de l’interdiction.

Or une société ne choisit jamais entre un risque et l’absence de risque.

Elle arbitre entre plusieurs risques.

Interdire une substance peut conduire à utiliser davantage d’un autre produit, à multiplier les passages agricoles, à déplacer les productions vers des pays moins exigeants ou à fragiliser certaines filières.

Ces effets doivent eux aussi être évalués.

La science ne promet pas le risque zéro.

Elle doit mesurer les expositions, quantifier les probabilités et comparer les différentes options.

🙏🙏

[Slazac 🇪🇺🇺🇦🇹🇼🌐 @TrueSlazac]

Getting dogwalked by a washed Belgium after getting the president to rig the game, maybe the most embarrassing performance of this tournament

[🍁☘️Canadian Fletchy 🇨🇦 @Darth_Pingu]

BREAKING: They've changed the name