Keely Oltion

PhD in Chemical Biology @ UCSF

[Susan Shao @sshaolab]

A small molecule degrader of the translation termination factor eRF1 = a metal-dependent molecular glue on ribosomes
Learn more here! https://t.co/SVJoXkz8SP

[Keely Oltion @keely_oltion]

@RuggeroDavide Thanks so much, Davide!

[Keely Oltion @keely_oltion]

Huge thank you to @JordanCarelli, Tangpo Yang, and @wanghychemistry in the lab, and our wonderful collaborators @stephanieksee and @MartinUCSF from the @KampmannLab.

[Keely Oltion @keely_oltion]

I'm delighted to present this story from the Taunton lab @UCSF in its final form! https://t.co/CVZXgvb7bd

[Keely Oltion @keely_oltion]

We combine chemical biology, functional genomics, mass spectrometry, and biochemistry to uncover a new ubiquitin signaling pathway at the ribosome, including two newcomers to the ribosome quality control field, RNF14 and RNF25, and the ribosome collision sensor GCN1.

[Manutder @wanghychemistry]

Thrilled to share this exciting story of SR-A3 -- started from organic chemistry, to chemical biology, biophysics, and cancer biology. (1/3)
https://t.co/vOd5mVsuHS

[Keely Oltion @keely_oltion]

This was done with contributions from a fantastic group of people, @JordanCarelli, Tangpo Yang, @wanghychemistry, and @stephanieksee and the @KampmannLab.

[Keely Oltion @keely_oltion]

Incredibly excited to share my graduate work, and the latest from the Taunton lab @UCSF! We think this will open a new dimension of surveillance pathways for elongating ribosomes.

https://t.co/C58yX9pYtk