If the government shutdown does not end very soon, many NIH study sections AND council meetings will be postponed. No council meetings = no grants funded. This would be a terrible hit for many US scientists. Reopen the government! #ScienceMatters@SenSchumer@LeaderJohnThune
Cardiomyocytes upregulate genes related to antigen presentation in myocarditis but not borderline myocarditis. This work led by @CharlieCohenPhD , Harriet Li, @kevchh89 from @hopkinsheart@HopkinsMedicine points to novel diagnostic and therapeutic options for myocarditis.
What are the strongest predictors of HFpEF? @kevchh89 applied machine learning to large HFpEF cohorts (thanks to @KSharmaMD and @HFpEF). We found that BMI, GFR, LA/LV ratio, and LVM indexed are the strongest predictors of HFpEF, especially in high BMI https://t.co/Ylosc9oxak
New preprint! contribution from @JLovellMD @luigiadamomdphd
Who could imagine B cells were doing that?!
Absolutely mind-blowing! 🤯
https://t.co/GTGZsOEssb
We report that patients with anti-Ku positive Abs and scleroderma-myositis overlap are at high risk of myocarditis and arrhythmia. Congratulations to case-series lead @JuliePaikMD, co-authors @AashikBhalodia@kevchh89#cardiacimmunology@hopkinsheart https://t.co/gBtLsfryQl
Now in the journal of the American Aging Association (Geroscience): cardiac stress results in systemic inflammation, that might be initially adaptive but eventually drives cardiac aging. #interorgancommunication#cardiacimmunology @hopkinsheart https://t.co/0SD6Qhc0oQ
Great to see a large proportion of my PhD studies finally out in press! This was a large collaborative effort that we hope will provide a rudimentary framework for cardiac non-myocytes in the context of type-2 diabetes induced cardiomyopathy.
Thanks to all who made this possible
We integrated single-cell datasets from healthy human hearts (45), DCM hearts (75), and ARVC hearts (8). We learned that B cells occupy a unique, dynamic, biological niche, with disease-specific features
https://t.co/u8XBJT6KdG Great work @kevchh89@c_duque18! @hopkinsheart
Per serum proteomic profiling, #PeripartumCMP is an inflammatory disease marked by dysregulation of inflammatory & cholesterol metabolism-related pathways, w/ activation of RXR-mediated pathways potentially contributing to cardiac recovery. https://t.co/VuUVe8JNcB
#JACCHF #CardioObstetrics #CardiacImmunology #ACCCardioOB
We have a new an intriguing paper on the actuation of single downstream nodes in growth. The study demonstrates how the Ras signaling network can steer immune cell migration, bypassing the chemoattractant receptor/G-protein network. Fascinating findings! @DhimanPal8#immunology
Congratulations to the team behind the groundbreaking study on mosquito behavior! Their paper 'Human scent guides mosquito thermotaxis and host selection under naturalistic conditions' is a significant contribution to the field. Well done! @dags263 @stephrankin2 #MosquitoResearch