Our latest study in @EditorNeuro demonstrates that dynamic FET-PET outperforms static metrics in distinguishing early recurrence from pseudoprogression in #GBM@NeuroOnc@EANOassociation
https://t.co/LXfctReZD4
Rewatching #BreakingBad in 2025 with fresh eyes as #Radonc resident☢️
Let's talk about how Walter White's Stage IIIA lung adenocarcinoma would be treated if diagnosed today instead of 2008. 🧵 #lcsm#MedTwitter
Because honestly? The show may look very different. Here's why...
In this week’s @JAMAOnc - full published paper of a randomised trial of craniospinal vs involved field RT in treatment of leptomeningeal metastatic disease
➡️ PFS 8.2 vs 2.3 months, p<0.01
First trial that has really shifted the dial in this difficult clinical setting. #RadOnc
🔗 https://t.co/su8ABP9laA
🧠 👉New clinical practice guideline in The Lancet Oncology. Out of the RANO group, we are proud to present our updated multidisciplinary, evidence-based guideline on PET imaging in patients with glioma.
https://t.co/rIe4t8leR0
🔗 #NeuroOncology#PETimaging#Glioma#RANO
Here new recommendations for the use of PET imaging in patients with gliomas from RANO working group and the @EANOassociation
Update to the RANO working group and EANO recommendations for the clin... https://t.co/a73x5vIXpC
@SapienzaRoma@galldiks
Another dogma is disappearing: SRS is effective for SCLC BM.
Stereotactic Radiosurgery in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases: A Multi-Institutional, Phase II, Prospective Clinical Trial | Journal of Clinical Oncology https://t.co/D08loaWWb3
Congats to my residents Raffaella De Pietro and Lucy Zaccaro per this interesting review on #journalofneurooncology: The evolving role of reirradiation in the management of recurrent brain tumors https://t.co/dHNCkTqIAu
Multi-Institutional Atlas of Brain Metastases Informs Spatial Modeling for Precision Imaging and Personalized Therapy, published in Nature Communications.
👉 Read it before your patients: https://t.co/EfQF5uvWl1
@NatureComms
Honoured to contribute to @BrainSci_MDPI Special Issue on “Advances in Neuro-Oncology”. Published just in time for Brain Tumour Awareness Month.
Full-text: https://t.co/khGgJ1KGrV
#GBM#DTI#Radiomics#Connectomics
Another study supporting efficacy and safety of reirradiation... Many data indicate similar scenario for Primark brain tumors and metastasi.. waiting for @Legato_Horizon results on GBM reirradiation and lomustine vs lomustine alone
@EORTC@SapienzaRoma@EANOassociation
🔥 Can SABR work twice?
Meta-analysis shows in-field #SABR reirradiation offers 78% 1-year control with low toxicity—especially for small tumours, high BED (≥200 Gy), & long intervals.
💡 A safe, effective salvage option for recurrent #NSCLC.
📖 https://t.co/cyxuzGFvl9
#radonc
What about toxicity?
Pneumonitis ≥ Grade 2: 6.4%
Grade 3 events: rare
Grade 4–5 toxicity: only in central tumors
➡️ Peripheral lesions had excellent safety profiles.
Key takeaway: location matters for reirradiation safety.
Pleased to share our latest work in @RO_GreenJournal
In-field lung re-SABR achieves excellent outcomes with low toxicities.
Size, dose, timing matters. Best results seen in recurrent tumours <2cm, cumulative BED ≥200 Gy, and interval >12 months.
https://t.co/rbNWRazrMu
So what predicts better outcomes?
✅ Tumor size <2 cm
✅ Cumulative BED ≥200 Gy
✅ Interval >12 months between SABR courses
Size. Dose. Timing. All critically influence local control.
📢🚨 Hot off the press @TheLancetOncol for #kidneycancer! https://t.co/v4fXO17tLp. SABR vs thermal ablation;
- Despite ⏫age, ⏬worse GFR, and ⏫tumours for SABR
- SABR ⬆️effective than TA (at 1, 2 and 5 yrs)
- esp for RCC >4cm
- same renal decline (p=0.75)
- similar F/U #radonc
Fellow lung cancer providers:
Who’s ready to try and memorize the 9th Ed staging which is now in place?!
Some notable changes:
-N2a & N2b
-Not all N2 = stage III
-M1c1 & M1c2
Ready or not…here it comes…