🚨 This is a prime example of fraud and waste inside California's homeless industrial complex
California bought this hotel for $8 million in 2020 and now wants $20 million to fix it. That is $625,000 per homeless person.
6 years later and NOTHING to show.
EXPOSE IT ALL.
We now have a female Bryan Johnson.
It’s Kate Tolo.
She will become the most measured female in history.
+$2 million of spend per year
+ Developing a female-specific protocol
+ Sharing everything for free
To start, she will spend 3 months mapping her baseline. Men, in contrast, can get their baseline done in 1 or 2 weeks.
+ 3 months for baseline measurement
+ across 4 time points per cycle
+ doing the same thing every day
+ a dedicated full-time medical team
For context on the extensiveness of measurement, during the past 5 years, we’ve collected 1.5 billion data points on my body. I suspect Kate will exceed that given technology has improved since I started.
The goal is to create a repeatable waveform of hundreds of life-critical biomarkers. Once the baseline is acquired, she will begin interventions.
We will try to answer practically useful questions and share all of the data + learnings for free.
Can fertility be improved?
+ Should women cold plunge?
+ Can PMS symptoms be alleviated?
+ What should a female sauna protocol be?
+ Should dosage change throughout the month?
+ What keeps a cycle regular?
+ Does the body need more iron, magnesium, or protein at specific phases?
+ Should women fast?
+ Should recovery protocol change by phase?
+ What's the earliest detectable signal of perimenopause?
+ Can perimenopause be slowed?
+ How is cognitive load & mood affected?
+ Does stress impact men and women the same?
Kate has suspected endometriosis. 10% of all women do. We will try to tackle this too. I am excited for all of the surprising things we will hopefully uncover.
Unlike me, Kate does not have the innate desire to wake up at 4:30am and do six hours of longevity therapies.
She’s the cofounder of Blueprint, building in the trenches with me since day one. She understands the game and how hard it is.
In many ways, this is a sacrifice for her. She is a creative person, going from a life of freedom and spontaneity to a rigid protocol.
Traditionally, RCTs have been viewed as the gold standard. But RCTs have underserved women. The FDA banned women from clinical trials for 16 years (1977 to 1993), and most "medicine for women" is still medicine tested in men. Demanding RCT-only evidence for women's health is demanding evidence that doesn't exist. There is not enough practical scientific literature for women to reference only RCTs. It leaves half the population without a path to know what to do.
N=1 medicine is gaining ground and picking up where RCTs specifically fail. Individual science experiments give us signals that answer what to do on a day-to-day basis. This is even more important for women.
If you’re new to Kate and my world, I want you to understand that we have your back. Our intentions are to be a sturdy, reliable force in your life. To care for your best interest as we’d care for our own. We want what’s best for you and our loyalty is to your existence.
It’s pretty cool to be living in a time when we may be the first generation to not die. I’m not suggesting immortality, but lifespans so long that we stop thinking about lifespans.
At the end of the day, the one thing we each care about more than anything else is one more breath. I’m proud of Kate for taking on this responsibility. It’s painful, exhausting and costly.
The beginning of the world’s first n=2.
Spotted in the NYC subway. “Zero screen time.” An iPod Shuffle ad in 2026.
When we built the iPod, the goal was the technology disappeared and you could have your music wherever you were. 1,000 songs in your pocket.
Now we’re living through a moment where people are actively looking for ways to disconnect from the infinite feed, algos, and constant notifications. That doesn’t mean technology is bad. It means the best technology understands when to step back.
Not every problem needs another screen, another menu, or another layer of complexity. Constraints create freedom (read: @DavidEpstein new book Inside the Box). And often removing features creates a better product than adding them.
The future of technology shouldn’t just be more engagement. It should help us be more human.
hiring a content writer for @Chanceappsocial 🫶
looking for a sharp, original writer who thinks outside the box — fluent in gen z + high school internet speak, clocks tiktok trends before they peak
$30-$45 an hour DOE, remote (CA preferred) no AI
Reply or DM for details!!
You have no experience.
You’ve never started a company.
You’ve never had a full time job.
Nike is going to kill you.
You’re a kid.
You don’t have technical skills.
You shouldn’t build hardware.
Apple is going to kill you.
You can’t build hardware.
You can’t measure heart rate non-invasively.
Athletes don’t care about recovery.
Under Armour is going to kill you.
It won’t be accurate.
You don’t listen.
You’re an ineffective leader.
You can’t recruit great talent.
You’re going to have to pay every athlete.
You can’t measure sleep non-invasively.
It’s too expensive to research.
Athletes are a small market.
The product costs too much to make.
The product costs too much to sell.
Your valuation is too high.
Consumers aren’t going to want it.
Hardware is too hard.
You should measure steps.
Fitbit is going to kill you.
You can’t build a marketing engine.
You can’t raise enough money.
You need a real CEO.
Google is going to kill you.
You can’t be a subscription.
You can’t build a brand.
You can’t do consumer in Boston.
Your valuation is too high.
You shouldn’t make accessories.
You shouldn’t make apparel.
Lululemon is going to kill you.
You can’t predict Covid.
Stay in your niche.
You are going to run out of money.
You can’t build a health platform.
Amazon is going to kill you.
You can’t measure blood pressure.
You can’t get medical approvals.
The market is too small.
You don’t understand AI.
The market is too competitive.
It won’t work internationally.
The supply chain is too complicated.
You can’t build an AI.
You can’t raise enough money.
It’s too competitive.
Healthcare isn’t going to want it.
…
Just keep going ✌️
🚨MIT researchers have mathematically proven that ChatGPT’s built-in sycophancy creates a phenomenon they call “delusional spiraling.”
You ask it something, it agrees. You ask again, and it agrees even harder until you end up believing things that are flat-out false and you can’t tell it’s happening.
The model is literally trained on human feedback that rewards agreement.
Real-world fallout includes one man who spent 300 hours convinced he invented a world-changing math formula, and a UCSF psychiatrist who hospitalized 12 patients for chatbot-linked psychosis in a single year.
Source: @heynavtoor
The AGI bogeyman is a distraction.
Most enterprises and governments can't even get models into production today. The real story of AI isn't autonomous superintelligence; it’s 25,000 humans in 100 countries training models to solve real problems.
This is the age of synthetic intelligence—not sci-fi.
@francispedraza
#ArtificialIntelligence #AI #Reality #Synthetic #Intelligence #EnterpriseAI
The difference between those who lived it and those who read about it.
The people who suffered most are celebrating the most.
Free Iran. Free women. God bless America ❤️🤍💚