firecracker

dead astronaut in space 🇮🇱 🇺🇦

[firecracker @kneedull]

“Confronted with people who have power, and who enjoy using it, I turn into a different person, a baser and meaner one.”

[firecracker @kneedull]

@Acyn being a complete piece of shit is the only job these losers have ever had but they’re really good at it

[firecracker @kneedull]

@SecretaryWright lol big ol portrait mode old ass

[firecracker @kneedull]

@GenericSubs @GergelyOrosz why don’t you learn how to read and understand why there’s a difference between things that are different?

[firecracker @kneedull]

“President Donald Trump abruptly canceled an event to sign a bipartisan affordable-housing bill Wednesday, announcing the ceremony was off as he fumed about the Senate not passing his bill to impose new rules on elections.”

real exemplar of the christian faith

[firecracker @kneedull]

@koanchuk @vxunderground oh shit you’re right my bad

[firecracker @kneedull]

Therapists, at least in the US. cannot prescribe drugs. Additionally, anxiety disorders are dramatically *under-diagnosed* and *under-treated*. Why do you think otherwise? You are saying things that are demonstrably false.

https://t.co/Jnb7CKu3fO

Also, there are severe risks GAD, panic disorder, major depression, agoraphobia, etc, with or without treatment of any kind. Very few of those risks are increased in any meaningful way by use of benzos to treat them. Perhaps you don't know about these, so I took the time to make you a chart that shows the actual danger of having GAD, panic disorder, which has a high chance of leading to major depressive disorder, agoraphobia, and alcohol substance abuse. This is all based on reliable sources, but I didn't want to bulk up the chart by citing them. If you'd like to see them, I would be happy to list them in reply to your request for me to do so.

[firecracker @kneedull]

afaik, propranolol only helps the physical symptoms like shaking and sweating (which is why it's kind of a controversial drug, possibly a performance-enhancing drug in certain environments, like debate club or especially things like musical performance). it blocks adrenaliine, but it does not treat the psychological or cognitive aspects of anxiety or panic disorder. My panic disorder led to me vomitting every day for instance, propranolol did not help that.

[firecracker @kneedull]

Two modeling papers from Paul Burkat (2022, 2023) looked at why benzodiazepines wreck short-term memory. The damage tracks how fast the drug spikes in the brain, not the size of the dose, or the specific drug (etizolam is not technically a benzo, it's "a potent thienodiazepine derivative, a class of drugs closely related to benzodiazepines")

He built models predicting brain concentration over time, then lined them up against human data on amnesia, sedation, and cognitive slowing.

The sharpest demonstration uses one drug in two forms. Immediate-release alprazolam reaches the brain in about 23 minutes. The extended-release version takes around 3.8 hours to get to the same level. Cognition took a clear hit on the fast formulation. On the slow one it held up, even when the dose was higher.

The diazepam paper modeled amnesia as its own endpoint, and the pattern repeated. When brain levels rose fast, that's when memory dropped out.

So the practical read: a benzo's memory cost comes mostly from a steep, sudden peak in the brain. Drugs that come on slowly and clear slowly spare memory far more than fast, sharp-peaking ones.

Worth being upfront about two limits. These are computational models checked against existing human data, not new trials, and they cover alprazolam and diazepam, not the whole class. The mechanism holds across both.

Links:
https://t.co/0I19BTLlCO
https://t.co/s3yoKsnwJT

Comparing this drug with klonopin on the parts that matter for amnesia (as your experience seems to be primariy about)

[firecracker @kneedull]

the doctor may have said that but that is absolutely untrue. see the asam guidelines for benzodiazepine tapering. it directly refutes this idea, as it has contingency plans for when to stop a taper if the person is struggling with it and when to start again. these doctors are demonstrably wrong, you should not spread their misinformation about something so serious

[firecracker @kneedull]

doctor prescriptions are not promises from god about the way the universe works. if someone is properly prescribed a medication regimen of any meaningful dose of benzos for longer than a month, abrupt discontinuation is absolutely a distinct risk as you will be physically dependent and need to taper down under close supervision. people given klonopin for seizures, properly prescribed, take like 20mg/day. if they abruptly stop, they are highly likely to die. taking as prescribed is not a safe harbor from biology

[firecracker @kneedull]

suboxone is an opioid tho btw. if your doctor keeps records of his clinical reasoning for those meds, and it’s sound, no reasonable doctor should or even can assume you have substance use disorder.

if you are taking benzos AND opioids, you should be extremely careful and probably get a second opinion just to be sure it’s safe. benzos alone basically never lead to overdose. benzos plus alcohol or opioids kicks that risk of overdose into the stratosphere.

[firecracker @kneedull]

addiction is not a medical term. it would be substance use disorder if anything which has a multi layer diagnostic criteria and instruments to conduct the analysis. addiction is a “vibes” word that is not used in actual medical literature, specifically the DSM.

if what you’re talking about is physical dependence, please be careful to not consider yourself safe based on your subjective experience. the asam benzo guideline for tapering says that people who take benzos for more than a month are highly likely to be physically dependent which if discontinued suddenly can lead to seizures, BIND and/or death

[firecracker @kneedull]

please consider filing a state medical board complaint against your doctor to prevent other people from enduring the hell and risk you were forced to go through. this is malpractice and goes against many standard ethics rules all doctors must adhere to. every single medical association considers this a violation of the standard of care, and could also count as patient abandonment amongst other very serious charges.

[firecracker @kneedull]

@Ozziecraf @vxunderground taking benzos when you are in withdrawal does stop withdrawal. it doesn’t stop any damage that is already done though, obviously. where are you getting the idea that taking a benzo doesn’t stop withdrawal?

[firecracker @kneedull]

that doesn’t do anything to prevent seizures from withdrawal or the risk of BIND just fyi. it is not safe to rapidly discontinue benzos after more than a months use. it risks seizure and death. vitamin b does help with the edge feeling that feels like you haven’t slept in days but the real risk is seizure and BIND which there is no protection from except a slow taper. this is literally on the black box warning for benzos

[firecracker @kneedull]

@koanchuk @vxunderground that was xanax, which while a benzo, has many differences pharmacologically that make it much more dangerous than klonopin

[firecracker @kneedull]

all states except i think one have a state controlled prescription monitoring database where all scheduled drugs prescribed and dispensed must be logged and any ER doctor is obligated to consult it as part of the risk/benefit assessment. you don’t need to bring in your bottle at least in the united states. they already have access to it and should have looked it up before even seeing you

[firecracker @kneedull]

@DawnOfSunset @vxunderground i think the benzo specific syndrome is called BIND but it is a form of PAWS as the previous person to reply said

[firecracker @kneedull]

the drug has risks, yes, and the requirements are for the prescribing doctor to regularly assess those risks and determine a safe way to get you off of them if necessary. that’s the stop gap / safety net designed to prevent situations like yours. please resist the urge to condemn a drug that is helpful without harm to many people, when the problem isn’t the drug, it’s your doctor and pharmacist acting out of compliance with their legal obligations. i also think, though i don’t expect any action to be taken on it, that what you have said could be considered giving medical advice and thus practicing medicine without a license. by making such dramatic and alarming statements as you did, it risks causing real harm to patients either on the drug or considering it.

i am saying this in good faith and not to argue, but to try to let you know about things you might not know about that are feeling your beliefs and statements and to let you know about the proper mechanisms to ensure patients are protected from from the harm you’ve suffered - by filing appropriate complaints to the appropriate authorities who will take this extremely seriously and have the power to discipline or even revoke the license of careless doctors. i’m also speaking from my own experience, and i would welcome you to DM me if you are interested in any specifics or how to file complaints, which does not require a lawyer or payment to anyone whatsoever.

in any case, i wish you luck. getting off of benzos, especially rather quickly, is extremely difficult and it’s a very brave thing to do. the guidelines linked above are the definitive guidelines on how to successfully taper off of them - going too fast risks failure and ending right back into the hellscape you’ve been living in. i truly hope this is helpful information for you and hasn’t come across as anything but a good faith attempt to tell you about all the things i’ve learned in my own experience with klonopin

[firecracker @kneedull]

1) it’s nearly impossible to overdose on benzos without an additional cns depressant like alcohol or opioids. your statement about them killing tons of celebrities, i’d challenge you to find just one instance where another cns depressant wasn’t mixed with it, primarily alcohol or opioids.

2) it is not like rat poison in any way. i think it demonstrates that you are either wildly exaggerating or you don’t understand how rat poison or benzos work. rat poison works because rats are incapable of vomiting, and so it only takes something like anticoagulants, bromethazine which is a neurotoxin that causes cells to not get the energy required to live, massive doses of vitamin d3 which floods their bodies with more calcium than they can survive etc.

3) your experience with abrupt withdrawal is a documented risk, even on the klonopin box label from the fda. if your physician let you go into withdrawal that is absolutely known to risk seizures and death, your physician has likely committed malpractice and if an er doctor refuses to give it to a documented long term benzodiazepine user who is clearly physically dependent, that doctor also has likely committed malpractice as that is contrary to the asam guidelines which has been adopted as the operative standard of care for physicians , as well as some basic ethics of not acting to prevent the possibility of serious harm to a patient, which in this case is possible life altering seizures with the possibility of death (similar to how if you drink a lot for a long time, you face this same risk. your state surely has a prescription monitoring database which the ER doctor is bound to consult to see if you have been prescribed the drug long term and are thus at risk of withdrawal and seizure.

4) if your doctor didn’t warn you about the risks, and neither did the pharmacist who dispensed it, that is a clear violation of many medical requirements, the strongest one would likely be failure to establish informed consent. i’m not questioning your experience, but when i pick up any meds with risks, there is, every time, an fda mandated description of the risks associated with that medication.

5) i assume your doctor did not conduct the mandatory every-3-months individual assessment to determine if your dose is appropriate, if you should taper or stay on the same dose. if they didn’t, that is another violation of the standards of care according to the benzo guidelines that have assumed de facto standard of care as it was developed by the association for addiction medicine as well as the american psychiatric association and has been endorsed by 10 similar associations. it was created through a roughly $2M grant by the FDA to specifically avoid the disaster that happened due to the opioid crackdown that backfired at basically every level, to try to prevent a similar thing happening with benzos. you can download it here https://t.co/KGcaYdYwJ2

6) i would strongly advise you to file complaints against your doctor through the board of medicine as well as the ER doctor who refused to treat you for the serious risk of seizure during withdrawal. i would also highly recommend filing similar complaints against any pharmacy and pharmacist to the board of pharmacy (both boards will be state-specific, so just do a lookup for your state board of medicine complaint as well as the board of pharmacy. your evidence doesn’t have to be trial ready, these are complaints that will dispatch the proper investigators to determine whether your doc or pharmacy violated the stan of care, which can if found true, lead to discipline up to and including revocation of their license. don’t just do this for you, do it to protect all the patients these providers have and will likely harm by their unethical and illegal behavior. their lack of doing what is required of them when prescribing or dispensing controlled substances is the actual cause of the hell you have experienced, not the drug.