Akbarrr

👾

[sosmed keras @sosmedkeras]

Hmhmhm

[Oren Gottfried, MD @OGdukeneurosurg]

Nerve repair

[Akbarrr @knightarmor7]

Aing maung ciah

[sosmed keras @sosmedkeras]

aowkaowk

[comunista de iQ+ ☭ @medicomunista_]

spoiler: não

[🍉 @txtdarijasputih]

Kemenkes hadirkan perbaikan besar untuk dokter internsip

Dengan cara: DITUNDA

Ditunda perbaikannya, menunggu semua lupa dulu

[dokterbedahYK @DokterbedahYK]

Digeruduk anggota dprd yg mayoritas hanya lulusan SD/SMP sambil petantang petenteng "mana direktur kamu?"

[MBG Jelek @menuembegejelek]

Potret lulusan SMA yang nilai mapel mipa sama bahasa Inggrisnya kerap dikatrol oleh gurunya:

[Dosen Pembimbing @Dospemz]

Mohon izin, saya coba bantu rapikan mind mapping-nya menjadi versi yang lebih sederhana, supaya alurnya lebih mudah dibaca 🙏

[Rafael Sirera @ProfSirera]

Yesterday we dealt with transferrin: the molecule that keeps iron soluble, transportable and safely escorted through plasma, (https://t.co/WQ6daNo9Zh).

Today we move to ferritin — often described as an “iron marker”, although that phrase hides much of its biology.

Ferritin is not simply a laboratory number.
✳️ Inside cells, it is the main architecture for iron storage: a 24-subunit nanocage composed of H and L chains, encoded by FTH1 and FTL.

Its logic is elegant.

Iron is indispensable for oxygen transport, mitochondrial respiration, DNA synthesis and many enzymatic reactions, but free iron is chemically dangerous.
In its ferrous form, Fe²⁺ can participate in Fenton chemistry, amplifying oxidative stress. Ferritin solves this contradiction by converting Fe²⁺ into Fe³⁺ through the ferroxidase activity of the H chain, while the L chain favours nucleation and mineralisation of the iron core. In other words, ferritin does not merely store iron; it detoxifies it.

✳️ But plasma ferritin is a different story.
The ferritin measured in blood carries little iron compared with intracellular ferritin. Its rise does not always mean “iron excess”.
Mild hyperferritinaemia often reflects inflammation, macrophage activation or tissue stress. During infection or inflammatory signalling, cytokines such as IL-1β and IL-6 reshape iron handling.
Hepcidin increases, ferroportin is downregulated, and iron becomes retained within macrophages and hepatocytes. This reduces extracellular iron availability — a defence strategy known as nutritional immunity — but it also raises ferritin.

This explains a common clinical paradox: a patient may have normal or high ferritin and still have insufficient iron available for erythropoiesis.
In absolute iron deficiency, ferritin falls because stores are depleted. In functional iron deficiency or anaemia of inflammation, ferritin may be preserved or elevated, while transferrin saturation is low because iron is trapped rather than accessible.

That is why ferritin should never be read as a binary signal.
Liver injury, obesity, chronic infection, autoimmune disease, malignancy, haemolysis and macrophage activation syndromes can all elevate ferritin through different mechanisms.

Ferritin is therefore best understood as an integrative biomarker: part iron reserve, part inflammatory signal, part cellular stress footprint.
Its value lies not in the number alone, but in the biological context it forces us to reconstruct.

[kale @kalistohenituse]

meanwhile habibie pas rupiah melemah & krisis moneter:

[🍑 @xopch]

Sudah banyak dokter yg akhirnya milih kerjaan lain, atau minimal punya kerjaan sampingan. Ada juga yg jadi dokter cuma pas weekend, sekedar biar ga lupa ilmunya aja. Kerja kantoran di sektor tertentu lebih menggoda, lebih minim resiko, dan lebih minim drama sama keluarga pasien.

[op @jaehyungantenk]

Masih bingung poli dokter spesialis 24 jam ini esensinya gimana…

Dokter spesialis loh ini… di RS tipe something… pasien poli kan bisa ditunda… paling gak sampe besok kan ya…

Poli… spesialis… 24 jam………��…

[ciaa @xpeacessea]

isi pikiranku saat ini:

[Samuel Hume @DrSamuelBHume]

Protect the liver, and the liver will protect the heart

[Dr Honey choudhary 🩺 @Doctors__squad]

The easiest way to memorize heart anatomy by hand..

[Valtoré⚕️ @Valtorewrites]

Don't stop until they call you a “DOCTOR”

[CardiovascularCorner @TrackYourHeart]

Cardiac cycle 😍😍