"...the denial that kratom use does not result in fatalities is false and misleading. Mitragynine has been confirmed as the sole toxicological finding in overdose deaths and has played a role in other adverse effects..."
https://t.co/4w2nziOAqY
@andrewlnye The case always was combined toxicity w/ kratom listed second. Guessing game w/ the amount of DHP post mortem redistribution but at the max range the 3 drugs wouldn't of killed. Also guessing how much cross CYP inhabitation led to toxic accumulation. Kratom COD with 3 others.
@andrewlnye The case always was combined toxicity w/ kratom listed second. Guessing game w/ the amount of DHP post mortem redistribution but at the max range the 3 drugs wouldn't of killed. Also guessing how much cross CYP inhabitation led to toxic accumulation. Kratom COD with 3 others.
Benadryl well-known to often have false inflated levels. This study looked at 113 drugs w/ 320 postmortem cases. Of all drugs studied DPH, had highest maximal C/P ratio, reaching up to 21X from reality via peripheral draws. Not obvious Benadryl overdose. https://t.co/QHo6MKz9vF
The fact this bill passed at all, tells me how corrupt some of these politicians can be.
They aren’t stupid, they can put 2+2 together and know the guy died from a Benadryl overdose. Yet they still passed the kratom ban.
They must be getting some kind of kick back money or something from this.
Benadryl well-known to often have false inflated levels. This study looked at 113 drugs w/ 320 postmortem cases. Of all drugs studied DPH, had highest maximal C/P ratio, reaching up to 21X from reality via peripheral draws. Not obvious Benadryl overdose. https://t.co/QHo6MKz9vF
The study will make mitra a prescription drug, kratom's primary alkaloid regulated by scheduling. Booze & kratom ≠ on history, pharmacology, reg pathways, etc. Comparing booze mostly "whataboutism". DHSHA/KCPA not sufficient. Human lethality a range now, animal LD50 known. https://t.co/eA5UPYpTdA
Proves our point: That NIH study shows mitragynine is a powerful psychoactive that is strong enough to be a prescribed drug with doctor prescreening and physician oversight with controlled doses and purified content behind a pharmacy counter. Ton of industry studies with COIs.
However anyone interprets this subjective. The fact that it's getting traction and is being considered for OUD is promising. The FDA is absolutely NOT industry funded, so "their" biggest argument is in the toilet. #KeepKratomLegal
https://t.co/ssdS9uLWa2
@CorralChad@LeafWithTaylor@Ch52471437Wendy Not moving goal posts. Always said booze & kratom ≠ on history, pharmacology, reg pathways, etc. Comparing booze mostly "whataboutism". DHSHA/KCPA not sufficient. No regs proposed improving safety enough other than kratom by prescription. Booze still bad for public health.
@andrewlnye There are issues with the studies, like this link. I am not saying there is widespread number fudging, it is more systematic bias in industry funded studies to design research and frame results to put things in most favorable light for kratom.
https://t.co/0UcOEAWZAL
@OGKratomQueen The study has valid flaws & limitations. We don't let the tobacco industry study their own products than declare them safe. The same standard applies to the kratom industry. The results were framed in a positive way in part because Pinney is paid like $200K per/yr. Neutral look:
@scoobthethinker It means it will be prescribed to screen for health conditions/prescriptions, the doses will be controlled/purified, a month supply at a time, ongoing clinical guidance, etc. Plus it will have passed a bunch of safety steps in humans before being on the market.
@CorralChad@LeafWithTaylor@Ch52471437Wendy It is NOT a double standard. Kratom & alcohol are not equivalent. I will admit booze is way more toxic and burden on society. DSHEA supplement rules/KCPA is not sufficient for kratom.
@CorralChad I am honestly not following you. I am arguing the NIH study shows mitragynine is powerful enough to be a drug & won't be sold OTC. I haven't made claims about the amount of kratom consumed in kratom deaths, just that these fatalities exist and the are a public health concern.
@andrewlnye@watchful_eye_s@HaddowMac@KratomKills I was answering someone's question about her credentials, hence the focus on that. This is Wendy's response to the actual session. https://t.co/fPkjm4RifK
@watchful_eye_s@HaddowMac@KratomKills With all due respect, she is retired nurse practitioner, w/ doctorate. No toxicology, forensics, poisonings, death investigation, etc. either by training or employment. AND a real expert is these would NEVER do a public case analysis like this for a lobbying org.
@watchful_eye_s@HaddowMac@KratomKills With all due respect, she is retired nurse practitioner, w/ doctorate. No toxicology, forensics, poisonings, death investigation, etc. either by training or employment. AND a real expert is these would NEVER do a public case analysis like this for a lobbying org.