HIGHEST RANKED TRIALS for 2025
TOP 10 #cancerclinicaltrials in 2025 w/MOST Impact
1/ #DeLLphi304@NEJM led by #Zeusofoncology@g_mountzios@HenryDunantGR : In relapsed SCLC post-platinum, BiTE DLL-3 Tarlatamab improved mOS vs. Chemo (13.6 vs 8.3 m, HR 0.60). PFS and in cancer-related dyspnea also improved.
https://t.co/dlIvlySUT9
Maintenance/consolidation with bispecifics. The talented Dr. Zamagni shows results if SRI. results are nothing but impressive. reminiscent of the data on ALL E1910. This is the way! Look at the MRD rates and PFS
#ASH24RF#MMSM
#ASH24 is a celebration of everything that makes #hematology extraordinary — breakthroughs and transformative data are shared amid moments of laughter and connection. 🩸✨
We can't wait to see what day 2 has in store!
. @MikkaelSekeres: I interviewed @ASH_hematology incoming VP, Cindy Dunbar (@cedunbar80) for ASH News TV! We discussed the highly anticipated plenary sessions at #ASH24. Stay tuned for more. 🤳🏼
Discontinuation of len maintenance based on MRD status. Most treated with triplets.A bit enriched for lower risk cases (by definition by being sustained MRD-)
#ASH24RF#MMSM
Speaking of variant detection: an elegant talk by @st_esquius showing that up to a *third of patients* (!) have P/LP germline variants, with the presence of symptoms/signs having a high PPV for finding something. #TestingMatters#ASH24#HemeTwitter