1 month in space ages a brain organoid 10 years on Earth. Alysson Muotri's lab at UCSD is using this insight to study neurological disease. In our latest BT epi, we discuss aging the brain in orbit and what brain organoids might mean for the future of AI.
link in comments!
I sat down with Rick Perry, former Governor of Texas, at this year’s Real Summit in NYC.
He's become a leading advocate for ibogaine and 5-MeO-DMT for mental and brain health. We discuss his personal experiences and his vision for legal plant medicine in the U.S.
Final Business Trip episode of the year. Link in the comments.
Mental health support is one of the top use cases for LLMs — so how can startups build AI that’s ethical, accessible, and scalable?
In this epi of Business Trip, we chat with Luis Voloch, co-founder/ceo of Jimini Health, a PsyMed portco building an AI platform that supports both therapists and patients with a behavioral health assistant that provides continuous care between sessions.
This conversation goes deep into what it really takes to building patient-facing AI in mental health.
Link in the comments.
Calling all entrepreneurial scientists! @PsymedVentures & @KdT_Ventures are co-hosting the 2nd annual Future Neuro Founders Program in October.
If you're interested in building a neuro startup, sign up here: https://t.co/f4sJQjlz2X
Speakers will be announced soon.
Skin2Neuron is pioneering a new approach to Alzheimer’s: taking cells from a patient’s hair follicles, turning them into neurons, and transplanting them into the brain.
Instead of managing symptoms, the goal is to replace damaged neural networks and rewire the brain from within.
In our new Business Trip episode, founder Brendon Boot describes the science, biz model, and regulatory path for this treatment. It's also a great primer on how cell therapies work. PsyMed is proud to have recently invested in Skin2Neuron.
Episode link in comments.
Mitochondria are in the spotlight as keys to energy production and a bunch of cellular functions deeply linked to aging, brain, and mental health. It’s also magical how they evolved from bacteria to an essential part of human cells.
We chatted with Natalie of Minovia about these topics and transplanting healthy mitochondria into patients even as a longevity intervention.
I’m intrigued by mitochondria and cell therapies because these treatments acknowledge complexity. Small molecules are mostly engineered to slot into one receptor. Cell/mito therapies remind us how little we understand about biology.
Episode link in comments.
Fun fact: Some people have a rare genetic mutation that lets them thrive on just 4–6 hours of sleep a night - and tend to live long, healthy lives with lower rates of diseases including Alzheimer’s.
UCSF’s Dr. Ying-Hui Fu studies these natural short sleepers. In our new Business Trip episode, she shares what makes them different, and whether the rest of us might one day tap into their superpower.
https://t.co/KAamHH7vOJ
New epi: What's wrong with US healthcare and how startups can fix it - w/ @jwmares
A while back @daisydwolf wrote that the biggest company in the world will be a consumer health tech company. I agree, Justin agrees. But it hasn't happened yet. Why? Among other things, the incentives and regulatory framework are flawed.
We discussed how to tackle the food system, environmental toxins, and pharma incentives.
We also think through startup opportunities in mental, brain, and physical health. Some of them are pretty out there!
Link to episode in comments!
I believe that VCs who founded their own firm are founders.
This creates a special bond between the founders we invest in.
We both have to fundraise, hire, and put out fires.
We’re both riding the same rollercoaster, just in different cars.