In the review we dive into the studies which used ECFC to understand the pathophysiology of bleeding disorders like von Willebrand disease and rare bleeding disorders.
@JTHjournal@SYMPHONY_NL @clotterdam @TromboseLeiden @rbierings #vWD#ecfc
Very happy to say that our comprehensive literature review on the use of Endothelial Colony Forming Cells (ECFCs) is now published! https://t.co/nvbsUvhIBi
Out now in @ThrombosisRese1
Our study showing the impact of allele-selective silencing of von Willebrand factor based on a single nucleotide allelic difference in VWF:
1) Thrombosis development is decreased
2) Bleeding times are not prolonged
https://t.co/bsHgfbbYzc
Allele-selective silencing of VWF using siRNAs is feasible based on 1 nucleotide difference within mouse strains. https://t.co/VexHGH4IAh #thrombosisandhemostasis#vascularbiology
With my amazing @TromboseLeiden colleagues we have been supporting #WorldThrombosisDay for the past 10 years! ✨
I've thoroughly enjoyed raising awareness at the fresh produce markets, @LUMC_Leiden science fair, A'dam flashmob, in my lab - with more to come!
#WTDay23#clotchat
Another day, another poster at the #ISTH2023! This time we tackle automated cell and organelle quantification using @CellProfiler. #PB1399@SYMPHONY_NL @clotterdam @TromboseLeiden
Discuss the possibities with me today at 18:30.
Desmopressin can give great results to prevent bleeding. But for some patients it's not effective. Join me at our poster at the #ISTH2023 to discuss the results on possible determinants of response. #PB0698@SYMPHONY_NL @clotterdam @TromboseLeiden @IrisMoort
SYMPHONY is on a roll at this year's #ISTH2023 in the beautiful Montréal. 5 oral presentations and 6 posters by Phds and Pi's! See the schedule below to follow our newest data live or watch the replay. @ryannearisz @laan_bas@MinkaZivkovic @rbierings @clotterdam @TromboseLeiden
This work is part of the @SYMPHONY_NL consortium and performed by @TromboseLeiden, @clotterdam, Richard Dirven, Petra Burgisser, Jeroen Eikenboom and @rbierings. Thanks to all involved!
@erasmusmcblood, @endothelialnews
Funded by @NWONieuws
Quantifying large numbers of cells and organelles can be a pain staking and time consuming process. A solution to this problem is automated quantification.
Our newly published paper in @PLOSONE offers this solution: https://t.co/OAMvfPRL1C
Please check out the full article to see even more functionalities of the pipeline https://t.co/OAMvfPRL1C
Interested in using this for your research? Feel free to reach out for possible collaborations!