Cancer dysregulates thousands of exons; some are drivers and could lead to therapies. But which ones?
Similar to VEP models for mutations, we model potential cancer driver exons genome-wide and predict exon fitness in cancer.
@NatureComms: https://t.co/6I9zZmTDxh
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It was really great to work with Yamile and Luis (@lab_serrano) on this project!
Check out our article if you want to know more about how to expose or secrete proteins with Mycoplasma pneumoniae: https://t.co/rgpPS8Qgne
It was really great to work with Yamile and Luis (@lab_serrano) on this project!
Check out our article if you want to know more about how to expose or secrete proteins with Mycoplasma pneumoniae: https://t.co/rgpPS8Qgne
🎉Congratulations to @piacosma and Luis @lab_serrano, who have each been awarded nearly one million euros by #CaixaResearch to drive groundbreaking research tackling blindness and lung metastasis.
🔗 https://t.co/QdkWpHk6Lt
New review from the lab! We take a look at the state of the field of bacterial Live Biotherapeutic Products. Congratulations to all authors involved. 🧫🦠 @IreRodArc@YamileAna2
https://t.co/hjCQYXkxKq
Today I'm presenting my project on @ECCBinfo! If you are interested in cytokine engineering, RNAseq data and mechanistic models come by poster 274 #ECCB2024
Happy to see this work out after a long journey. Prioritization and modeling + experimental validation of cancer-driver exons with therapeutic potential in different cancer types. Beautifully led by @m1quelag@CRGenomica@lab_serrano
Can we measure changes in splicing factor “activity”? 🤔
In complex samples like cancer, it's tricky because SF activity is regulated by more than just expression changes or mutations.
Check out our new collab between @lab_serrano and @califano_lab: https://t.co/ugKaGraVqd
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I am so happy to receive this award!! Thank you so much @UPFBarcelona
It is a great honour to share it with great colleagues from @CRGenomica 😍
And a special thanks to my great supervisors and mentors @lab_serrano@MartinHSchaefer for the exciting journey together!
Beyond thrilled to see one of @kourtisSavva's brilliant ideas published today in @ScientificData@NaturePortfolio
🔥🔥Detection of differential bait proteoforms through immunoprecipitation-mass spectrometry data analysis🔥🔥
https://t.co/qYmx5UNZjr
New work published today! We develop a platform for screening of biomedically relevant proteins in the fast-growing Mycoplasma feriruminatoris.
@CRGenomica@IOM_network@UPFbiomed
Find it here:
https://t.co/NoKo5GlwJw
New paper published! We report the engineering of safer strains of Mycoplasma pneumoniae that prevent Guillain Barre Syndrome to use as a chassis for therapy. Congratulations to the authors!
@cpl_synbio@CRGenomica@IOM_network
Find the full story here:
https://t.co/iF5AfxnpGi
Check out our #preprint on computational antibody design!
This work resulted from a wonderful collaboration between Luis Serrano Pubul (CRG), Dewilde Maarten (KU Leuven), Savvas Savvides (VIB, Ghent University) & VIB Switch Laboratory.
Read the preprint https://t.co/Dig84ThK77 describing a milestone in our de novo antibody design efforts.
Our pipeline can now design high-affinity and stable antibodies in a single round!
Fantastic collaboration with @lab_serrano@SavvidesLab & Maarten Dewilde @KU_Leuven
Excited to share our latest work on #smallproteins. We have designed an identification approach using #TnSeq that together other #omics and #bioinformatic approaches increases the number of genes of Mycoplasma pneumoniae from 690 to 997!
https://t.co/aFM4aURbif