serranoLab

Understanding complex systems at @CRGenomica

Tweets are from lab members 😎👨‍💻👩‍🔬👨‍🔬👩‍💻

[serranoLab @lab_serrano]

Congratulations to @m1quelag on his latest work!! A three-years-old project finally published!!

[Miquel Anglada-Girotto (m1quelag@bluesky) @m1quelag]

Cancer dysregulates thousands of exons; some are drivers and could lead to therapies. But which ones?

Similar to VEP models for mutations, we model potential cancer driver exons genome-wide and predict exon fitness in cancer.

@NatureComms: https://t.co/6I9zZmTDxh

🧵

[serranoLab @lab_serrano]

Congratulations to @YamileAna2 and @d_gerngross on their latest publication!

[Daniel Gerngross @d_gerngross]

It was really great to work with Yamile and Luis (@lab_serrano) on this project!
Check out our article if you want to know more about how to expose or secrete proteins with Mycoplasma pneumoniae: https://t.co/rgpPS8Qgne

[Daniel Gerngross @d_gerngross]

It was really great to work with Yamile and Luis (@lab_serrano) on this project!
Check out our article if you want to know more about how to expose or secrete proteins with Mycoplasma pneumoniae: https://t.co/rgpPS8Qgne

[HMar Research Institute @HMar_research]

The @HMar_research participates in one of the projects selected in the #CaixaResearch Health Research 2024 call

Dr. @TCeliaTerrassa will participate in a project led by @lab_serrano at @CRGenomica.

@CaixaResearch @FundlaCaixa

https://t.co/izWGpLh3t3

[Centre for Genomic Regulation (CRG) @CRGenomica]

🎉Congratulations to @piacosma and Luis @lab_serrano, who have each been awarded nearly one million euros by #CaixaResearch to drive groundbreaking research tackling blindness and lung metastasis.

🔗 https://t.co/QdkWpHk6Lt

[Mol Syst Biol @MolSystBiol]

review by @lab_serrano discusses bacteria-based live biotherapeutics ➡️ https://t.co/WuG62jRIjq

[Open Box Science @OpenBoxSci]

🎙️ Miquel Anglada Girotto's talk 📣
@m1quelag
@CRGenomica
@lab_serrano

https://t.co/dKmOJopvQw

#genomics #openscience

[serranoLab @lab_serrano]

New review from the lab! We take a look at the state of the field of bacterial Live Biotherapeutic Products. Congratulations to all authors involved. 🧫🦠 @IreRodArc @YamileAna2
https://t.co/hjCQYXkxKq

[Miquel Anglada-Girotto (m1quelag@bluesky) @m1quelag]

Catch @xavier_heal and I presenting our latest publications this coming thursday at the @OpenBoxSci seminar!

[Quim Martí @QMartiB]

Today I'm presenting my project on @ECCBinfo! If you are interested in cytokine engineering, RNAseq data and mechanistic models come by poster 274 #ECCB2024

[Ludovica Ciampi @__ludoC]

Happy to see this work out after a long journey. Prioritization and modeling + experimental validation of cancer-driver exons with therapeutic potential in different cancer types. Beautifully led by @m1quelag
@CRGenomica @lab_serrano

[BIST-Barcelona Institute of Science and Technology @_BIST]

Congratulations to the five #BISTCommunity researchers for their #ERCPoC grants in the latest @ERC_Research call:
🏅Eva Novoa & Luis Serrano @CRGenomica
🏅Gerasimos Konstantatos @ICFOnians
🏅Marcos García Suero @ICIQchem
🏅Samuel Sánchez @IBECBarcelona
➡️https://t.co/KKcpNCmg0z

[serranoLab @lab_serrano]

Check out the latest pre-print from the lab!

[Miquel Anglada-Girotto (m1quelag@bluesky) @m1quelag]

Can we measure changes in splicing factor “activity”? 🤔

In complex samples like cancer, it's tricky because SF activity is regulated by more than just expression changes or mutations.

Check out our new collab between @lab_serrano and @califano_lab: https://t.co/ugKaGraVqd

🧵

[Xavier Hernandez Alias @xavier_heal]

I am so happy to receive this award!! Thank you so much @UPFBarcelona
It is a great honour to share it with great colleagues from @CRGenomica 😍

And a special thanks to my great supervisors and mentors @lab_serrano @MartinHSchaefer for the exciting journey together!

[Sdelci Lab @SdelciL]

Beyond thrilled to see one of @kourtisSavva's brilliant ideas published today in @ScientificData @NaturePortfolio

🔥🔥Detection of differential bait proteoforms through immunoprecipitation-mass spectrometry data analysis🔥🔥

https://t.co/qYmx5UNZjr

[serranoLab @lab_serrano]

New work published today! We develop a platform for screening of biomedically relevant proteins in the fast-growing Mycoplasma feriruminatoris.
@CRGenomica @IOM_network @UPFbiomed
Find it here:
https://t.co/NoKo5GlwJw

[serranoLab @lab_serrano]

New paper published! We report the engineering of safer strains of Mycoplasma pneumoniae that prevent Guillain Barre Syndrome to use as a chassis for therapy. Congratulations to the authors!
@cpl_synbio @CRGenomica @IOM_network
Find the full story here:
https://t.co/iF5AfxnpGi

[serranoLab @lab_serrano]

Check out our #preprint on computational antibody design!
This work resulted from a wonderful collaboration between Luis Serrano Pubul (CRG), Dewilde Maarten (KU Leuven), Savvas Savvides (VIB, Ghent University) & VIB Switch Laboratory.

[Switch Lab @VIB_Switch_Lab]

Read the preprint https://t.co/Dig84ThK77 describing a milestone in our de novo antibody design efforts.
Our pipeline can now design high-affinity and stable antibodies in a single round!
Fantastic collaboration with @lab_serrano
@SavvidesLab & Maarten Dewilde @KU_Leuven

[Samuel MV @Samuel_BIO2810]

Excited to share our latest work on #smallproteins. We have designed an identification approach using #TnSeq that together other #omics and #bioinformatic approaches increases the number of genes of Mycoplasma pneumoniae from 690 to 997!

https://t.co/aFM4aURbif

[Miquel Anglada-Girotto (m1quelag@bluesky) @m1quelag]

Had a great time at this year's #JBG2023 presenting our work characterizing the cancer splicing programs! Our first @lab_serrano @califano_lab collaboration! Thanks for the feedback and inspiring discussions! @CRGenomica @Columbia @CosmoCaixa_CAT @SCB_iec @BiBcn