Excited to share a our collaboration with Curtis Henry’s group @WinshipAtEmory looking at the crosstalk between obesity, galectin-9, and chemotherapy resistance in B-ALL. https://t.co/hBxiWfxTzr
Chronic viral infection leads to a dysregulation of germinal center B cell responses. Di Pietro et al show deletion of BMI-1 in mature B cells promotes effective humoral responses to chronic viral infection and accelerates viral clearance. https://t.co/FDUPITK2a8
@KimLJacobson
#JI_TopRead: From Dr. Jeremy M. Boss’s group @EmoryMedicine | An IRF4–MYC–mTORC1 Integrated Pathway Controls Cell Growth and the Proliferative Capacity of Activated B Cells during B Cell Differentiation In Vivo | https://t.co/20YfGt0WDh #ReadTheJI
Check out our recent @J_Immunol publication investigating the cell division-coupled reprogramming events of IRF4 and it's impact on cell growth / proliferation during B cell differentiation.
BIG thanks to @jmboss12@cdscharer@jimrose835 Kania and Price!
https://t.co/909unYz3me
Check out the terrific lineup of reviews in the recent issue of Immunological Reviews focused on the unique biology of plasma cells. Also the cover image from our review - "Epigenetic gene regulation in plasma cells"
https://t.co/hhR5zWvzmw
w/ @jmboss12@LabScharer Anna Hong
Excited to share our latest research. Here we investigated the epigenetic differences between IgG and IgM memory B cells. One of our interesting findings was that human and mouse memory B cells engage the heme pathway. Pumping iron 💪 helps make ASCs! https://t.co/JhKzPCqF4f
New paper from our lab using in vivo models and scRNAseq to map B cell fate and identify markers that predict activated B cells destined to become ASC! @DG_Patterson @NatureComms https://t.co/HGYJUMlrQ3