Landry Shipman

DO One-time published sports writer

[Oklahoma Baseball @OU_Baseball]

THE OKLAHOMA SOONERS ARE NATIONAL CHAMPIONS 🏆

[Landry Shipman @land_ship]

@GeorgeStoia This is the game

[Landry Shipman @land_ship]

@Top100Rick Never get rid of trees.

[Landry Shipman @land_ship]

@joe3jax Gold and Emerald. Not Blue.

[Landry Shipman @land_ship]

@Bdrumm_OUI It’s unbelievable at this point

[Eric Topol @EricTopol]

For medical information, general AI frontier models (Google, OpenAI, Anthropic) outperformed specialized @EvidenceOpen and @UpToDate as assessed by 12 US clinicians, randomized and blinded to which model and extensive testing/benchmarks. This was not anticipated. @NatureMedicine
https://t.co/KCH1ADfQWz

[Landry Shipman @land_ship]

@TechAthletics

[Landry Shipman @land_ship]

@geoffschwartz He doesn’t care.

[Landry Shipman @land_ship]

@scottisaacsmd Incredible

[Landry Shipman @land_ship]

@ChipJohnson01 How was Diamante? HSV is a hidden gem

[Max Marchione @maxmarchione]

Retatrutide phase 3 obesity trial just came out and the results are genuinely insane:

- 28.3% bodyweight lost on 12mg over 80 weeks
- 70.3 pounds on avg. or 31.9 kg
- 45.3% of patients hit 30%+ weight loss (this is bariatric surgery territory)
- 30.3% weight loss (85 lbs) at 104 weeks in higher-BMI patients
- 65.3% of 12mg patients dropped below the obesity BMI threshold
- 19% loss on 4mg over 80 weeks (47.2 lbs) with fewer dropouts than placebo (4.1% vs 4.9%)
- significant drops in blood pressure, triglycerides, non-HDL cholesterol, waist circumference, and hsCRP
- no cardiac or liver signals

Retatrutide is going to completely overshadow tirzepatide and semaglutide, and take the throne as the best-selling drug of all time.

[Landry Shipman @land_ship]

@Josh_Scoop Chet is so weak

[Avi Roy @agingroy]

936 million people have sleep apnea. 80% don't know it.

It's not just snoring. Untreated, it accelerates biological aging, raises diabetes risk 40%, and drives cognitive decline through nightly oxygen deprivation.

For most patients, the answer was CPAP, a machine you strap to your face every night. Half of them quit within a year.

A once-nightly pill cut apnea events 44% in a 646-person Phase 3 trial (SynAIRgy, @apnimed). Works by tightening airway muscles during sleep. No weight loss. No sedation.

Tirzepatide got FDA approval for sleep apnea in Dec 2024 by reducing body weight. AD109 targets the airway directly. Two drugs. Two completely different mechanisms. Both work.

A disease affecting a billion people had no approved drug that treated the apnea itself until last year. It has two now.

[Joel M. Topf, MD FACP @kidney_boy]

OMG! It finally happened! Dapa is $8/month at @costplusdrugs

#Flozinator

Thank you @mcuban

[Landry Shipman @land_ship]

@ChipJohnson01 @GreenGCA @callahan_kyle On my bucket list.

[Landry Shipman @land_ship]

@RevWSJohnson

[Landry Shipman @land_ship]

@JasonFaires When are the greens being aerated? Looking to get out there soon!

[Landry Shipman @land_ship]

@KPalvia @DrNadolsky That’s awesome. You can do it!

[Landry Shipman @land_ship]

@forestmanjohn Brilliant