Laurent Gil

Software developer at Wellcome Sanger Institute

Current projects: @PGSCatalog & OmicsPred

[PGS Catalog @PGSCatalog]

A big day for ancestry-specific polygenic risk scores in the PGS Catalog, a phenome-wide atlas of scores for 241 traits (1501 PGS)! Check it out 🔗: https://t.co/wuvgJ0n2Mr!

[PGS Catalog @PGSCatalog]

New PGS for novel cardiac MRI traits derived using 3D diffusion autoencoders, released this week in the PGS Catalog 🔗: https://t.co/cT7TZMAPNZ

Thanks @SoumickAI for #FAIRdata sharing - find out how to share your polygenic score data @ https://t.co/pIDGyikNU7!

[PGS Catalog @PGSCatalog]

Now available in the latest release from the PGS Catalog: https://t.co/Zk19IqBzSM! Check out this scores & others, along with easy-to-use tools for reproducible PGS calculation @ https://t.co/63bPMToDLE #FAIRdata

[PGS Catalog @PGSCatalog]

Discover data from our latest release:
- New PGS for atrial fibrillation (https://t.co/bVGF8LWHIf)
- PGS optimised for East Asian ancestry in cancer (https://t.co/AUbgvnD9ab) and 10 other common diseases (https://t.co/10Y0StV6DJ)

Submit data at https://t.co/iF0CPGkOsz

[PGS Catalog @PGSCatalog]

Interested in calculating polygenic scores in the All Of Us workbench? Take a look at our new documentation for how to run pgsc_calc in the cloud environment: https://t.co/V70pUWWn17. Very much a work-in-progress, optimisations incoming!

[PGS Catalog @PGSCatalog]

📣 Thrilled to announce our collaborative tutorial with @EBItraining! Dive into the world of polygenic scores and explore the PGS Catalog resources (including pgsc_calc) - ideal for those seeking a comprehensive yet quick overview. Access it online at https://t.co/XbIODriufb!

[EMBL-EBI Training @EBItraining]

Polygenic scores can predict an individual’s genetic predisposition to certain traits or diseases. Join our #webinar learn how to use the PGS calculator for calculating polygenic scores. Registration is free but essential: https://t.co/Dyqs5gYt7u #genomics @emblebi @PGSCatalog

[Loïc Lannelongue @Loic_Lnlg]

🚨We're recruiting! Interested in making science and computing more environmentally friendly? Now is the time!

Very excited to build a research group at @Cambridge_Uni to expand our Green Algorithms work thanks to the support of the @wellcometrust

https://t.co/v0eh3TIIDU

[PGS Catalog @PGSCatalog]

Interested in software tools for calculating polygenic scores? @iamslambert & @nebfield are giving an @EBItraining webinar December 4th about our pgsc_calc tool and it's capabilities for reproducible PGS calculation: https://t.co/8eE3xiX7xY! Join in or catch the recording after.

[Sam Lambert @iamslambert]

A great day for #FAIRdata and polygenic score research - the @PGSCatalog continues to grow past 5000 scores!

In honour of the occasion @Florent_Yvon & I commissioned some AI art (you should see the ones we scrapped). A massive congrats to the whole https://t.co/FDKoTDXawK team!

[PGS Catalog @PGSCatalog]

>5000 Polygenic scores now available at https://t.co/63bPMToDLE! As of today's release we've broken 5k PGS, indexing data from 673 unique publications. A big thank you to the authors submitting their data and our team in pursuit of #openscience, #FAIRdata, and reproducibility!

[Sam Lambert @iamslambert]

Check out the latest developments of all things @PGSCatalog, out now in @NatureGenet (🔗: https://t.co/5rh06KUfGu )!

In this paper we describe big increases in the data content (and diversity) and our tool for PGS calculation (https://t.co/VB3xXP5EMb).

[Health Data Research UK (HDR UK) @HDR_UK]

📢 The Polygenic Score (PGS) Catalog has been updated, including data added from multi-ancestry or non-European populations and a PGS Catalog calculator.

The project is a collaborative effort between @Cambridge_Uni, @emblebi and @GWASCatalog.

Learn more: https://t.co/COLaDcCKA1

[EMBL-EBI @emblebi]

📣 New updates to the @PGSCatalog.

These include multi-ancestry data and a new Calculator to simplify PGS calculations across different ancestries. Learn more about how these updates could enable more equitable disease risk predictions.

https://t.co/Q0qZH4yLt8

[EMBL-EBI @emblebi]

Huge congratulations to everyone involved! @minouye271 @DrP_stuff @iamslambert Ben Wingfield, Joel Gibson @laurentgil33 @aoifemcm @HarrisWiseman @GWASCatalog @HDR_UK @CAMBRIDGE_CEU @BakerResearchAu and more.

Read the full @NatureGenet article here 👇
https://t.co/Xzi1mYAwRN

[BHF Cardiovascular Epidemiology Unit at Cambridge @CAMBRIDGE_CEU]

Out today in @NatureGenet!

Important new updates to the Polygenic Score (PGS) Catalog, & a new software tool that simplifies the calculation of polygenic scores in the context of genetic ancestry

👉 https://t.co/0OR1Lw7m0Z

@iamslambert @minouye271 @sritchie73 @Florent_Yvon

[PGS Catalog @PGSCatalog]

Last of the summer PGS, new metaPRS in our latest release:
- For T2D, including many evaluations from @sritchie73 @minouye271 et al https://t.co/SCILJupyyw
- New PGS for CAD, IS, ICH from China Kadoorie Biobank in @NatureHumBehav https://t.co/tfYR6feoIG

Stay tuned for fall 🍂!

[PGS Catalog @PGSCatalog]

Now available in the PGS Catalog: https://t.co/aHeJZQVDbG thanks to @jpirruccello et al for submitting!

Submit your score pre or post-publication/preprinting, more info at https://t.co/pIDGyillJF.

[PGS Catalog @PGSCatalog]

@TakaOjima @okada_yukinori @tchikowore1 We've also been hard at work on performance improvements to our PGS Catalog calculator software, check out the latest release on our GitHub (https://t.co/ahsG91SKVn) and see our detailed documentation (https://t.co/ogXFcT3I37).

[PGS Catalog @PGSCatalog]

Some 🌞Summer PGS🌞 data for you in our latest release:

- BMI-stratified T2D PGS @TakaOjima @okada_yukinori https://t.co/x2EeaOV54B
- Multi-ancestry BMI PGS @tchikowore1 https://t.co/H8UVAtZ3D5
- Liver cirrhosis https://t.co/chS5sVSJGY

... & more @ https://t.co/8miwLLyrkz!