Pao-Wan Lee

PhD student - EPFL LBNC

[Pao-Wan Lee @leepaowan]

Hey synthetic biology folks!
We’ve developed a new T7 RNAP regulatory toolbox to help you build gene circuits!
It includes methods to design programmable repressors, activators, and biomolecule sensors — ready to integrate into your T7 RNAP-based cell-free systems.

[Maerkl Lab @MaerklLab]

Pao-Wan, Saeed and Matthis' paper is out now on BioRxiv:

"A T7 RNAP regulatory toolbox for cell-free network engineering and biosensing applications"

https://t.co/f7MCiZM6o9

[bioRxiv Synthetic Biology @bioRxiv_synbio]

A synthetic cell with integrated DNA self-replication and membrane biosynthesis https://t.co/k6hFzcy4XB #biorxiv_synbio

[Niko McCarty. @NikoMcCarty]

A neural network, made out of proteins and built in mammalian cells.

"we combined de novo–designed protein heterodimers and engineered viral proteases to implement a synthetic protein circuit that performs winner-take-all neural network classification..."

Congrats @ElowitzLab.

[Pao-Wan Lee @leepaowan]

Excited to share my first publication with the Maerkl Lab! 🎉 Our review offers a comprehensive overview of the mechanisms and applications of various regulatory methods. If you’re looking to construct gene regulatory networks or need components to start with, check it out!

[Maerkl Lab @MaerklLab]

Pao-Wan's review on cell-free regulatory components is out now!

Regulatory Components for Bacterial Cell-Free Systems Engineering | ACS Synthetic Biology https://t.co/z4Z0N8X3JW

[Pao-Wan Lee @leepaowan]

@shwzo Enjoy Dresden🙂

[Pao-Wan Lee @leepaowan]

@insitubiology @James_Saenz

[Pao-Wan Lee @leepaowan]

@SebastianMaerkl Also seen similar phenomena while pouring tea into tea cup

[Maerkl Lab @MaerklLab]

Improved Cell-Free Transcription–Translation Reactions in Microfluidic Chemostats Augmented with Hydrogel Membranes for Continuous Small Molecule Dialysis

Barbora and Laura's paper is out now.

https://t.co/msgajKXYoU

[Martina Maritan @MartinaMaritan]

Getting ready for my talk tomorrow at @UUtah @janetiwasa, featuring my beloved whole-cell model of course 🤩

[St. Jude Research @StJudeResearch]

Scientists uncover the answer to a long-standing question in biochemistry: How do fatty-acid binding proteins deliver fatty acids to membranes? Read the @jbiolchem paper. https://t.co/nAoy3lN2Vx

[Sáenz Lab @LabSaenz]

Small reunion/and farewell to celebrate former PhD student @SandraRaouf starting her first job at @BiotypeDx and @leepaowan getting accepted at @EPFL_EDBB to start his PhD! Great way to end the week!! 🎉🎊🎈🍻

[Pao-Wan Lee @leepaowan]

@MaerklLab I'm interested in the PhD position! Hope we can have a chance to discuss about the project.

[J. Craig Venter Institute @JCVenterInst]

Scientists from the @UofIllinois @chemistryuiuc, JCVI, and @tudresden_de have developed a computer model of the minimized synthetic cell, JCVI-syn3A, that accurately predicts the growth and molecular structure of its real-life counterpart.

https://t.co/RaQ5bTw4p9

[Sáenz Lab @LabSaenz]

Our latest manuscript "Lipid membranes modulate the activity of RNA through sequence-dependent interactions" is... 🎉🎊 published 🎊🎉!! https://t.co/qnXYom0NGR

@t_czer_jea @James_Saenz @PNASNews @VolkswagenSt @BMBF_Bund @SimonsFdn @BCUBE_TUDresden