Hey synthetic biology folks!
We’ve developed a new T7 RNAP regulatory toolbox to help you build gene circuits!
It includes methods to design programmable repressors, activators, and biomolecule sensors — ready to integrate into your T7 RNAP-based cell-free systems.
Pao-Wan, Saeed and Matthis' paper is out now on BioRxiv:
"A T7 RNAP regulatory toolbox for cell-free network engineering and biosensing applications"
https://t.co/f7MCiZM6o9
A neural network, made out of proteins and built in mammalian cells.
"we combined de novo–designed protein heterodimers and engineered viral proteases to implement a synthetic protein circuit that performs winner-take-all neural network classification..."
Congrats @ElowitzLab.
Excited to share my first publication with the Maerkl Lab! 🎉 Our review offers a comprehensive overview of the mechanisms and applications of various regulatory methods. If you’re looking to construct gene regulatory networks or need components to start with, check it out!
Pao-Wan's review on cell-free regulatory components is out now!
Regulatory Components for Bacterial Cell-Free Systems Engineering | ACS Synthetic Biology https://t.co/z4Z0N8X3JW
Improved Cell-Free Transcription–Translation Reactions in Microfluidic Chemostats Augmented with Hydrogel Membranes for Continuous Small Molecule Dialysis
Barbora and Laura's paper is out now.
https://t.co/msgajKXYoU
Scientists uncover the answer to a long-standing question in biochemistry: How do fatty-acid binding proteins deliver fatty acids to membranes? Read the @jbiolchem paper. https://t.co/nAoy3lN2Vx
Small reunion/and farewell to celebrate former PhD student @SandraRaouf starting her first job at @BiotypeDx and @leepaowan getting accepted at @EPFL_EDBB to start his PhD! Great way to end the week!! 🎉🎊🎈🍻
Scientists from the @UofIllinois@chemistryuiuc, JCVI, and @tudresden_de have developed a computer model of the minimized synthetic cell, JCVI-syn3A, that accurately predicts the growth and molecular structure of its real-life counterpart.
https://t.co/RaQ5bTw4p9