Jeff Lewis

Interested in understanding how organisms sense and respond to stressful environments, and why some individuals are more sensitive or more resilient. he/his

[Jeff Lewis @LewisLab]

New preprint from the lab exploring global 'acetylome' remodeling during heat shock in yeast, led by @rhardman215, with strong support by @AaronStorey4.

https://t.co/hWOM7u9LuS

[Max Kozlov @maxdkozlov]

Jason, this is all public government data pulled directly from NIH RePORTER. Berg isn't even in the story

The bottom line is that the White House has not yet allowed NIH to spend its research funds from the spending bill passed almost a month ago, impacting grant awards

[Jeff Lewis @LewisLab]

This is really fucking simple. Don’t as law enforcement officers in a matter of seconds shove people onto the ground, pepper spray their faces, and then start beating the shit out of them. That’s escalation and excessive force.

[Jason Granger @JasonEGranger]

@SarahisCensored Instead of saying "I believe this should have been handled much differently from the beginning" why don't you offer up a solution?

It's easy to be an armchair quarterback.

[Michael Tracey @mtracey]

If these guys are going to charge around like maniacs, pushing people so hard they fly into the snow, and then reflexively blast pepper-spray, all within seconds, they either have catastrophic lack of self-control, or have deliberately chosen to rapidly escalate these situations

[Jeff Lewis @LewisLab]

@arjunrajlab Wondering now if folks bragged about doing math by hand when calculators came out.

[Jeff Lewis @LewisLab]

@mbeisen Whoa, are those the original yeast clusters?

[Jeff Lewis @LewisLab]

@arjunrajlab Big if true

[Jeff Lewis @LewisLab]

The application deadline closes at the end of the week. Apply to join our awesome department.

[Jeff Lewis @LewisLab]

Very excited to announce that our department is now accepting applications for a tenure track faculty position in Cell Biology: https://t.co/puaGzXNhaa

Come join our wonderful department!

[Lana Garmire 🌶 @GarmireGroup]

Have #LLM models for #singlecell omics really been adopted by #biomedical community and enabled new scientific discovey? What more efforts to make?
Plz check out our comment article published by @NatureBiotech this week. https://t.co/iDpFP4iF9X

[Jeff Lewis @LewisLab]

@OdedRechavi It’s impossible for me to disentangle that grants = the livelihoods of the people in my lab. So grants, and it’s not even close. Preprints have also taken much of the pressure off of publishing—the papers are out there, and people can read them.

[José Aguilar-Rodríguez @jaguilarrod]

One of the most exciting projects of my career, years in the making. Using high-throughput precision genome editing, we mapped the fitness effects of thousands of natural variants—challenging the idea that common variants are inconsequential.
https://t.co/l7cMJWikk4

[Jeff Lewis @LewisLab]

@pastramimachine and my grant is getting a whole different kind of not discussed

[Joseph Schacherer @jo_schacherer]

✨ Latest exciting story of @haploteam in @Nature. Here, we go beyond SNPs and built a species-wide atlas of genetic variants in yeast. With >1,000 near T2T genomes, we show how SVs shape the phenotypic landscape.
@InstUnivFr @ERC_Research @CNRSbiologie
https://t.co/RE7ec6K6Ru

[Jeff Lewis @LewisLab]

Very excited to announce that our department is now accepting applications for a tenure track faculty position in Cell Biology: https://t.co/puaGzXNhaa

Come join our wonderful department!

[Jeff Lewis @LewisLab]

Very excited to announce that our department is now accepting applications for a tenure track faculty position in Cell Biology: https://t.co/puaGzXNhaa

Come join our wonderful department!

[Anshul Kundaje @anshulkundaje]

I was on an H1B during my postdoc and research scientist years. I currently have exceptional PDs & staff scientists in my lab who are on H1Bs who have and are major contributors to the research output of the US. This is utterly stupid and idiotic. 1/

[Genetics Society of America @GeneticsGSA]

New paper in #G3journal from @mongemmmm, @MeruSadhu, and colleagues presents a barcode-based high-throughput method that can track large numbers of independent replicates of a small number of combinatorial genotypes. https://t.co/5kQ7FWTRLH

[Stelkens Lab @StelkensLab]

We have a new paper out in Molecular Ecology, led by @DevinBendixsen ! Reproductive isolation due to divergent ecological selection is accompanied by vast genomic instability in experimentally evolved yeast populations https://t.co/ig1xUm8Qit

[Julie Stenken @JulieStenken]

We are excited to announce an opening in any chemistry area for Fall 2026 at the rapidly growing U of Arkansas. Apply by 15 Nov. Happy to chat with anyone. @Chemjobber https://t.co/lER8cpnyCZ

[Michael Baym @baym]

Every few months the "good lab hands" thing comes up and it misses a key point: you can learn to have good hands. Training matters.

Good hands aren't some magic gift from the PCR gods, you have to develop them through directed repetitive practice, like any other skill

[Arjun Raj @arjunrajlab]

It's fun to think about this little diagram again many years after drawing it. It occurs to me that the very notion of "mechanism" is an intrinsically biological concept, in many ways a byproduct of the mostly causality-based style of science inherent to the field.