The future of nephrology will be shaped by bold ideas, outstanding young investigators, and sustained investment in research. Congratulations to all the 2026 @KidneyCure grant recipients!
I am especially proud of my fellow, @chenyu Chenyu Li, whose NephroBase project aims to improve causal AI foundation models of the human kidney by integrating molecular, spatial, pathology, and clinical data into a unified platform for discovery. https://t.co/3TL0lSZ0MO future of kidney research is bright. https://t.co/F35uKlRA2f
🚨 Our new paper just dropped !!! Proteomic risk score for early prediction of kidney disease progression in individuals with APOL1 high-risk genotypes https://t.co/4WCXVKst5S
So proud of Elias Ziyadeh the son of legend @FuadZiyadeh of his research accomplishments at he lab of Homer W. Smith 2025 awardee and role model Dr. @KSusztak
@ASNKidney #KidneyWk
🚨 Kidney + AI milestone 🚨
Never been more excited to share!!!
We built Nephrobase Cell+, the first multispecies, multimodal kidney foundation model:
Trained on ~40M cells
Across 4 species (human, mouse, rat, pig)
From 5 modalities (scRNA, snRNA, snATAC, CosMx, Xenium)
Kidney biology finally has its own GPT moment.👇
Myeloid EGFR deficiency accelerates recovery from AKI via macrophage efferocytosis and neutrophil apoptosis | @NatureComms Ray Harris https://t.co/zLmeBZiQAb
In the Literature (@NatureComms) commentary by Chenyu Li and @KSusztak:
Genetic Insights into Blood Pressure From Kidney Multi-Omics
https://t.co/ozZuHO5972 (FREE)
@PennMedicine
In the Literature (@NatureComms) commentary by Chenyu Li and @KSusztak:
Genetic Insights into Blood Pressure From Kidney Multi-Omics
https://t.co/C3crnor787 (FREE)
@PennMedicine
Happy to share our latest work on acute kidney injury induced by cholesterol crystal embolism, which triggers TMA-like lesions @CRC_TRR332 @BloodJournal @Linkermann_Lab
👉GSDMD drives focal crystalline TMA via immunothrombosis and necroinflammation
https://t.co/WY09KIC8hV
Now free online in @CKJsocial
A significant no of pts develop AKD without AKI (slower onset) but AKD has a similar impact on mortality, CKD and subsequent ESKD
https://t.co/XKVsdiAmWZ
@CZjqCNGw4XmHfIa
Inhibitors of the renin-angiotensin system (RAS), SGLT-2, and the mineralocorticoid receptor (MR) were superior to dual RAS/SGLT2 blockade in attenuating CKD progression in a mouse model of Alport syndrome https://t.co/Tn5IHSKP2g
@hjanders_hans@RosKaroAT@cirluigi @LaBOORatory
Super excited to share our new paper Unified Mouse and Human Kidney Single-Cell Expression Atlas Reveal Commonalities and Differences in Disease States by Jianfu Zhou https://t.co/ulvPlp8gj6
Everyone speaks about AKI, few speak about AKD, but many pts develop AKD w/o AKI. AKD +/- AKI has important consequences on mortality and subsequent CKD.
Incidence and prognosis of AKI versus AKD among 71,041 inpatients https://t.co/21a9cOKw9N
Science article discussing the crucial role of polyploidy in stress response across evolution, but also in organ physiology, including our data about the kidney response to injury https://t.co/jqgbEgo1LV