Phil Finish

Lyophilization, told by a man who reads cakes not COAs. Mother Pucker Mondays. Frozen, not fried.

[Phil Finish @lifeoflyo]

@DisguisedAlpha Jack DM me pls.

[Phil Finish @lifeoflyo]

@VirtusPeptides We are using SP VirTis

[Phil Finish @lifeoflyo]

@VirtusPeptides Nice, how many 2R vials per batch in that lyo? China made?

[Phil Finish @lifeoflyo]

@PeptidePartners @TrustPointe @JoshInProgress Is this a peptide fill-finish facility with inhouse testing?

[Phil Finish @lifeoflyo]

@PeptidePartners Oh nice, in-house sterility testing

[Phil Finish @lifeoflyo]

@VirtusPeptides Partly. If it really was one solution batch filled at different volumes, the purity result can stand for every size. The mg per vial can't, because that's measuring the fill, so each size needs its own content test.

[Phil Finish @lifeoflyo]

@PeptidePartners @TrustPointe https://t.co/jjp6WP5kCu

[Phil Finish @lifeoflyo]

Primary drying is a long cycle. You have to fill the time somehow.

[Phil Finish @lifeoflyo]

Primary drying is a long cycle. You have to fill the time somehow.

[Phil Finish @lifeoflyo]

@n1after40 In my experience the grade and buffering of glutathione makes a big difference with regard to injection site pain and irritation.

Real parenteral grade glutathione pH buffered is near painless

[Phil Finish @lifeoflyo]

Remember when Eli Lilly sued six companies over retatrutide sales? There’s an interesting follow-up: Lilly withdrew its case against Astra LLC after the company showed it had nothing to do with Astra Peptides.

Lilly had taken the name from the peptide website’s legal terms and sued a Texas company with that name. It turned out to be a transportation business, not the website’s operator. That’s remarkably lazy identity checking before filing a lawsuit.

https://t.co/1QAI30qT7X

[Phil Finish @lifeoflyo]

@Krysia830073 Supplier confirmation gets difficult when the sample comes from an end user rather than the manufacturer. They may not know which excipients were added. How does Vanguard handle 'I don't know', as distinct from a declaration that none were used?

[Phil Finish @lifeoflyo]

@VirtusPeptides Virtus web design language is beautiful. What do the boxes look like?

[Phil Finish @lifeoflyo]

@VirtusPeptides I blame Joe Rogan 😂

[Phil Finish @lifeoflyo]

Why is benzyl alcohol in a freeze-dried peptide vial at all?

If it’s in the cake, it was in the liquid fill before drying. A preservative would usually go in the reconstitution solution. So why add it before lyophilization?

My working theory is that it’s being used to suppress microbial growth during fill-finish, where aseptic controls may be weak. Cosmetics-grade facilities in China are filling injectable peptide vials, which makes that possibility worth examining.

[Phil Finish @lifeoflyo]

I think you may have the wrong Hybio. Krysia's article is about grey-market peptide vials, not pharmaceutical peptides.

The real Hybio (https://t.co/sBGPGwWRD6) is a public pharma company making peptide APIs and generic drugs. They don't sell grey-market vials, so they don't affect the 95% figure.

The Hybio sites you see selling vials, like https://t.co/wdAkk6DStS, are fakes using the Hybio name and logo.

[Phil Finish @lifeoflyo]

@XovaNova_MD @Krysia830073 I've visited Hybio's impressive R&D facility in China. Correct me if i'm wrong. Hybio is an API manufacturer not a fill-finish facility?

[Phil Finish @lifeoflyo]

@OHMpeptides In my experience, 1,4-Butanediol is a good alternative to alcohol as a social lubricant.

[Phil Finish @lifeoflyo]

@PeptidePlugs Did you borrow that 4:1 ratio? https://t.co/scbqQp0gSJ

[Phil Finish @lifeoflyo]

GLP-4 | Eloralintide + Retatrutide blend

Last June, we brewed a batch of GLP-4. It’s a 4:1 blend of Retatrutide & Eloralintide. Interesting side effect reported, a number of lifelong coffee drinkers have quit drinking coffee on this blend 🤔

[Phil Finish @lifeoflyo]

@DexterXRP @Krysia830073 Propane Tank?

[Phil Finish @lifeoflyo]

@ManOnThePen @AbudBakri Elora + Reta is already available as a blend

[Phil Finish @lifeoflyo]

GLP-4 | Eloralintide + Retatrutide blend

Last June, we brewed a batch of GLP-4. It’s a 4:1 blend of Retatrutide & Eloralintide. Interesting side effect reported, a number of lifelong coffee drinkers have quit drinking coffee on this blend 🤔