Laboratory of Immunometabolism (LIM)

The @MoraeaPedro lab aims to understand how metabolism shape the function of tissue macrophages to unveil new therapeutic targets to treat diseases.

[Pedro Moraes Vieira @MoraeaPedro]

Our new manuscript is out. Here we describe one potential mechanism related to severe COVID-19 in people with obesity.

Obesity‐Induced Metabolic Priming Exacerbates SARS‐CoV‐2 Inflammation - Davanzo - Immunology - Wiley Online Library https://t.co/xzCa9PN13o

[Pedro Moraes Vieira @MoraeaPedro]

Our new manuscript is out.
Here we describe one potential mechanism involved in the increased severity of autoimmune disease in obese people.
Obesity increases blood-brain barrier permeability and aggravates the mouse model of multiple sclerosis https://t.co/urN0uskADS

[Pedro Moraes Vieira @MoraeaPedro]

It was a pleasure and fun time to write this News and Views highlighting a cool paper by Ira Tabas and co-authors @NatMetabolism

[Laboratory of Immunometabolism (LIM) @LimImmumet]

AMPK and PKM2 define metabolic function of adipose tissue, hepatic and splenic tissue iNKT cells

[Pedro Moraes Vieira @MoraeaPedro]

We are thrilled that our paper is out, great work performed by @cris_f_aguiar
@CellReports @sbi_imuno @AgenciaFAPESP @unicampoficial
@emrcluster @CepidOcrc
Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury https://t.co/5FHq5GfESi

[Laboratory of Immunometabolism (LIM) @LimImmumet]

2022 LIM celebration!

[Pedro Moraes Vieira @MoraeaPedro]

One more year with this great team.
Great time with good science. The best way to end this - almost back no normal - year!

[SBI - Imunologia @sbi_imuno]

#SaveTheDate O próximo congresso anual da Sociedade Brasileira de Imunologia (SBI) já tem data e local definido!

O evento será realizado entre os dias 01 e 05 de outubro no Centro de Convenções da Universidade Federal de Ouro Preto (Minas Gerais).

Anote na agenda!

[Peter J Murray @pjmurray_lab]

https://t.co/J2ypNKIrwu This is a beautiful and creative paper about copper acquisition from the Fass lab @FassLab

[Laboratory of Immunometabolism (LIM) @LimImmumet]

"Inter-organ transport of adipocyte-derived mitochondria" - Mitochondria 😎

Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood https://t.co/zzN6D0AtJm

[Laboratory of Immunometabolism (LIM) @LimImmumet]

All about tissue macrophages 😎

[Immunity @ImmunityCP]

(1/5) Special collection this month on #macrophages in tissues! Collection of 4 reviews, focusing on gut, lung, heart, and liver macrophages. https://t.co/LvKA2WQbFQ

[Pedro Moraes Vieira @MoraeaPedro]

Cool paper, dismantle biofilms is a big deal

[Laboratory of Immunometabolism (LIM) @LimImmumet]

What a nice work from our Team

Leptin shaping the metabolic adaptation of tissue macrophages

https://t.co/nQjTlsnIQH

[Agência FAPESP @AgenciaFAPESP]

Estudo ajuda a entender por que #obesos tendem a desenvolver complicações metabólicas como #diabetes. Resultados de experimentos com camundongos conduzidos por cientistas da @unicampoficial e colaboradores podem orientar a busca por terapias. https://t.co/tfH6eWOhfF

[Immunity @ImmunityCP]

What was it like to start a lab during a pandemic? We asked new principal investigators to share their experiences navigating this new landscape, how they adapted, & what advice they can share with others in similar situations #Voices #newPI https://t.co/RP6cWLI3HG

[Agência FAPESP @AgenciaFAPESP]

Tratamento conhecido como inibidor de checkpoint imunológico, já usado contra certos tipos de #câncer, mostra potencial para tratar casos graves de #COVID19 em testes pré-clínicos. Detalhes sobre o trabalho estão descritos em @ScienceAdvances. https://t.co/82qmBUSFBT

[Laboratory of Immunometabolism (LIM) @LimImmumet]

Our paper is out, PD1/PD-1L axis in COVID-19 and its regulation by the NLRP3 inflammasome.

Great collaboration with Marcelo Hill and team!

https://t.co/avcAc2ZPbp

[Laboratory of Immunometabolism (LIM) @LimImmumet]

Leptin Signaling Suppression in Macrophages Improves Immunometabolic Outcomes in Obesity https://t.co/WH54sn1Cdl