Linda Rafferty 💙💛 🇮🇪 🇪🇺

[Chris Hadfield @Cmdr_Hadfield]

Imagine being on a spacewalk experiencing this.
The upper tendrils of Earth's aurora reach high enough that we fly right through them. I felt so small, floating between our planet & the universe, surrounded by this, as we start to permanently leave home.
Filmed by @Soph_astro of @esa through the windows of the International Space Station last week.

[Visit Galway @visit_galway]

When you're driving down the road and you stumble across a beautiful little beach... 🏖️💙

📸 IG/ nathan_exploress
📍 Ballyconneely, Connemara

[David Blevins @skydavidblevins]

Veronica Guerin (5th July 1958-26th June 1996). The bravest of journalists, murdered by cowards. Never forgotten. ❤️

[ScienceInFocus @SciInFocus]

They didn't kill the cancer. They told it to go home.

A team of Korean scientists at KAIST just pulled off something that sounds like science fiction.

Instead of nuking colon cancer cells with chemo or radiation, they convinced them to turn back into normal, healthy colon cells.

No killing. No collateral damage. Just a quiet U-turn at the cellular level.

Here's how it works.

Led by Professor Kwang-Hyun Cho at the Department of Bio and Brain Engineering, the team built a "digital twin" of the gene network that controls how a normal cell becomes cancerous.

They ran simulations. They hunted for the exact moment a healthy cell flips into a malignant one.

Then they found the switches.

Three master regulator genes — MYB, HDAC2, and FOXA2 — were the keys to the whole transformation.
Flip those switches back, and the cancer cell stops behaving like a cancer cell. It starts looking and acting like a normal enterocyte, the kind of cell that lines a healthy intestine.

No gene editing. No permanent rewiring. Just the body's own natural signals, used in reverse.

The team confirmed it in molecular experiments, cellular experiments, and animal studies. The malignant cells stopped multiplying out of control and went back to doing their actual job.

The research has already been handed off to a company called BioRevert Inc. to develop into real-world treatments.

This isn't a cure tomorrow. But it rewrites the entire playbook for how we think about cancer.

You don't always have to destroy the enemy.

Sometimes you just have to remind it who it used to be.

Source: KAIST / Advanced Science (Gong et al., 2024) via ScienceDaily and OncoDaily

[Chris Hadfield @Cmdr_Hadfield]

Artemis re-entry, seen from the International Space Station!
Very cool: the @sen camera mounted on ISS caught sunglint off the returning lunar Orion capsule "Integrity" just as it was entering Earth's atmosphere.
We live in an amazing world and time.
ISS streaming: https://t.co/RXcIhUQ0yC

[Interesting things @awkwardgoogle]

Just in case you’re having a bad day, remember this is how they weigh koalas 😍

[Curiosity @CuriosityonX]

Full rotaton of Moon:

[Curiosity @CuriosityonX]

708 GB image of the Moon 🌑

[Physics & Astronomy Zone @zone_astronomy]

POV: View of the earth from the moon surface.

[N @Abbergelig]

Tom Crean sailed a life boat with 5 other men across the most hostile sea in the world, and then trekked 3 days over frozen mountains with nothing but a pickaxe, a rope, and shoes retrofitted w/ nails.

They saved the Endurance crew stranded 900 miles south.

I think of him often.

[RTÉ Nationwide @RTENationwide]

The Kerry woman making a real difference in Tanzania - a graduate of @UCC - Louise Quill is changing lives through the charity she founded @tirnanogtanz - we meet her on #RTENationwide Friday 20th March on @RTEOne at 7pm @Kerrys_Eye @kerryman_ie @KerryHour @radiokerrynews @rte RT

[Linda Rafferty 💙💛 🇮🇪 🇪🇺 @lindamrafferty]

@ChathubDep_DE Can't dm you

[Linda Rafferty 💙💛 🇮🇪 🇪🇺 @lindamrafferty]

@Ryanair does anyone know if it matters that you don't get your confirmation email after booking? Email not in spam. But booking is in my ryanair portal. Trying to connect to customer care but it's about 2 hrs now waiting to hear

[Linda Rafferty 💙💛 🇮🇪 🇪🇺 @lindamrafferty]

@Ryanair the chat support on ryan air website... I've tried twice. 300 plus customers ahead of me and then it disconnects when it gets down to around 80

[ALASTAIR CAMPBELL @campbellclaret]

You keep thinking the Trump grift machine cannot get any worse … and then it does. Incredible how the US media lets this stuff go. And how the U.K. media gives Farage a free pass on it all too given he is Trump’s man in London

[Lissadell House @LissadellHouse]

Remembering the work of Eva Gore-Booth and her sister Countess Markievicz of Lissadell, on this International Women's Day

Their memories kept alive by Constance Cassidy of Lissadell

#InternationalWomensDay

[Linda Rafferty 💙💛 🇮🇪 🇪🇺 @lindamrafferty]

@irishelt Thank you

[Curiosity @CuriosityonX]

Sea otters hold hands when they sleep so they don't drift apart, a behavior known as rafting.

[dominic dyer @domdyer70]

Today, @IUCNRedList officially declared the Slender-billed Curlew extinct, marking the first known global extinction of a formerly widespread migratory bird species whose range included mainland Europe, North Africa, and West Asia.

“The extinction of the Slender-billed Curlew...underscores the urgency of implementing effective conservation measures to ensure the survival of migratory species. Hopefully, the loss of this species will help galvanize action to protect other threatened migratory species,” said CMS Executive Secretary Amy Fraenkel @curlewcalls