Lisa Koch

[Lisa Koch @lisa__koch]

I am so excited my PhD work is out in @NatMetabolism!

We show that elevated cytosolic pH promotes cell proliferation by transcriptional activation of cyclin D1!
👉https://t.co/F09xN0OgJd

Many thanks to @r_dechant and all co-authors @EivindBirk @MdCurioni @IsaOpitz @PeterLab8

[Kim Fabiano Marquart @marquark]

Our TnpB story has been published in @naturemethods 🚀 Check out the thread by @schwanklab to dive right in.

[Kim Fabiano Marquart @marquark]

Check the @naturemethods research briefing associated with our latest study on TnpB for effective genome editing
https://t.co/zmIfUECkxo

[@PeterLab @PeterLab8]

The final version of mitosis specific CUL4B function is now published @embojournal.

In addition, we show CUL4B depletion impairs brain development in beautiful forebrain organoids.

Congrats to all the authors and collaborators 🎉
https://t.co/bDnwXtT4Ez

@ETH_DBIOL @ETH_en

[Kim Fabiano Marquart @marquark]

🎙️Excited to launch my new podcast #CRISPRli, a deep dive into the revolutionary world of #CRISPR. I'll be hosting interviews with top genome editing experts. Ideal for scientists, students or anyone curious about this cutting-edge tech. #GeneEditing
https://t.co/cJR4KbjY14

[@PeterLab @PeterLab8]

Protein paralogs perform specific functions? Check our new preprint https://t.co/DM2ElKrbZ4 from lab headed by talented @StierAnna, Samuel @weaam_i

CUL4B plays #mitosis-specific functions using #phosphorylated & #disordered N-ter Extension.
#Ubiquitination #IDPs
@ETH @ETH_DBIOL

[Lisa Koch @lisa__koch]

@LabThoma @weaam_i Great job @weaam_i 🤩

[Lisa Koch @lisa__koch]

Fantastic work! Congrats @marquark @sharan_janjuha, Ahmed and collaborators!

[Kim Fabiano Marquart @marquark]

Excited to share our study on predicting base editing outcomes with attention-based machine learning published in @NatureComms. Huge thanks to our collaborators @krauthammerlab and all @schwanklab members. Special thanks to @sharan_janjuha and Ahmed Allam
https://t.co/9vMqHSkbPW

[Lisa Koch @lisa__koch]

Merck Innovation Cup 2021 - What an amazing experience! The last week has been a rollercoaster ride but in the end, we did an incredible job as a team winning the runner-up prize!
Thanks to all the experts from @merck_de for helping us shape our innovative idea!

[Lisa Koch @lisa__koch]

@tanjarothgangl @lukas_villiger @schwanklab Congratulations!

[Lisa Koch @lisa__koch]

@JoeySc1 Congrats 🎉

[Lisa Koch @lisa__koch]

Happy to contribute to this exciting collaborative project! Congrats @PatrikSimmler, @schwanklab and all collaborators!

[Patrik Simmler @PatrikSimmler]

I am happy to share our preprint about the #splicing factor SF3B1 that contributes to tumor malignancy by facilitating the adaption to hypoxia in solid cancers. SF3B1 interacts with #HIF1α and acts as a transcriptional co-activator. -> Thread (1/4)
https://t.co/u9rIErpMe7

[D-BIOL @ ETH Zurich @ETH_DBIOL]

In a recent @NatMetabolism paper the Dechant group (IBC) and collaborators reveal a mechanism implicating increased cytosolic pH as a driver for cell proliferation by transcriptional activation of cyclin D1. More details: https://t.co/kPt6vhra56

[Lisa Koch @lisa__koch]

@obenaufa Very nice talk!

[Nature Metabolism @NatMetabolism]

Online now! Cytosolic pH regulates proliferation and tumour growth by promoting expression of cyclin D1 https://t.co/PUwIKpCW68

[Lisa Koch @lisa__koch]

Excited to share our review: Another Consequence of the Warburg Effect? Metabolic Regulation of Na+/H+ Exchangers May Link Aerobic Glycolysis to Cell Growth @FrontOncology @EivindBirk @r_dechant https://t.co/dHwvhsWfSd

[Reinhard Dechant @r_dechant]

Very excited to share the first preprint of the lab! We describe a function of cytosolic pH in the regulation of Cyclin D1 transcription during cell proliferation and cancer #Cyclin D1 #mesothelioma

[Lisa Koch @lisa__koch]

Check out the first preprint of the @r_dechant lab describing a function of cytosolic pH in the regulation of Cyclin D1 transcription during cell proliferation and cancer! Thanks to everyone involved 🙌🏼 @PeterLab8 @MdCurioni @IsaOpitz

[bioRxiv Cell Biology @biorxiv_cellbio]

Coincidence detection of mitogenic signals via cytosolic pH regulates Cyclin D1 expression https://t.co/7ttaCQUuPx #biorxiv_cellbio