Abhishek Gupta

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. After 40, stop guessing about your health. These numbers tell you whether you're building a long, vibrant life — or quietly declining without knowing it.

I run these on myself. I run them on every patient I care about. Most are cheap bloodwork. All are available now. And together, they paint a picture no standard annual physical will ever give you. Print this. Bring it to your next appointment. Your 60-year-old self will thank you.
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𝗙𝗮𝘀𝘁𝗶𝗻𝗴 𝗜𝗻𝘀𝘂𝗹𝗶𝗻
Target: below 5 μIU/mL. Ideal: 3-4.
This is the 10-year warning bell your standard panel completely misses. Your glucose and A1c can look "normal" for a decade while your pancreas is working overtime to keep them there. Fasting insulin catches insulin resistance 5-10 years before your A1c moves. By the time A1c rises, the damage is already extensive.

𝗛𝗢𝗠𝗔-𝗜𝗥
Target: below 1.0.
Calculated from fasting insulin and fasting glucose. The single best measure of insulin sensitivity. Above 1.0 and your metabolism is already under strain. Above 2.5 and you're insulin resistant — even if every other number looks fine.

𝗛𝗯𝗔𝟭𝗰
Target: below 5.4%.
Not below 5.7% — that's the threshold where medicine calls you "prediabetic." By then you've been metabolically compromised for years. Optimal is below 5.4%. Blood sugar mastery is longevity mastery.

𝗧𝗿𝗶𝗴𝗹𝘆𝗰𝗲𝗿𝗶𝗱𝗲 : 𝗛𝗗𝗟 𝗥𝗮𝘁𝗶𝗼
Target: below 2. Ideal: below 1.
Your metabolic health crystal ball. This ratio predicts insulin resistance, cardiovascular risk, and metabolic syndrome better than any single lipid number alone. A ratio above 3.5 is a red flag regardless of what your total cholesterol says.

𝗔𝗽𝗼𝗕
Target: below 80 mg/dL for moderate risk. Below 60 for high risk.
I've written about this extensively. ApoB counts every atherogenic particle hitting your artery walls. A 2024 analysis found 54% of patients had dangerous levels that standard LDL testing completely missed. If you only know your LDL, you're driving with one eye closed.

𝗟𝗽(𝗮)
Test once in your lifetime.
100% genetic. 1 in 5 Americans are elevated. Triples heart attack risk independently of everything else on this list. Diet and exercise cannot lower it. The 2026 ACC/AHA guidelines now recommend everyone be tested. Most never have been.

𝗵𝘀-𝗖𝗥𝗣
Target: below 1.0 mg/L.
You can have perfect cholesterol and inflamed arteries silently preparing to rupture. hs-CRP measures the fire behind the plaque. The JUPITER trial proved that finding and treating inflammation saves lives — even when lipids look fine. If this number is elevated, your mouth, your gut, your metabolic health, and your visceral fat are the first places to investigate.

𝗩𝗶𝘁𝗮𝗺𝗶𝗻 𝗗
Target: 50-80 ng/mL.
Not the bare minimum of 30 your doctor accepts. Suboptimal vitamin D is linked to higher inflammation, weaker immunity, increased cardiovascular events, worse mood, and poorer outcomes across nearly every disease I treat. Supplement D3 with K2 — without K2, calcium deposits in your arteries instead of your bones.

𝗧𝗲𝘀𝘁𝗼𝘀𝘁𝗲𝗿𝗼𝗻𝗲 (𝗧𝗼𝘁𝗮𝗹 + 𝗙𝗿𝗲𝗲)
Men: optimal range 600-1000+ ng/dL total.
Declining testosterone is an independent predictor of cardiovascular death in men. It's tied to insulin resistance, arterial stiffness, visceral fat accumulation, and systemic inflammation. DHEA-S drops 10-20% every decade after 30. Tracking these isn't about vanity — it's evaluating your body's systemic resilience.

𝗕𝗹𝗼𝗼𝗱 𝗣𝗿𝗲𝘀𝘀𝘂𝗿𝗲
Target: below 120/80. Aim closer to 110/70.
Every point above optimal is cumulative arterial damage. Buy a home cuff. Measure morning and evening, seated quietly for five minutes, arm at heart level. White-coat readings in the office miss what's really happening. The smartest $40 investment in cardiac self-care.

𝗩𝗢𝟮 𝗠𝗮𝘅
Men over 40: above 40 mL/kg/min. Women over 40: above 35.
Cardiorespiratory fitness is the single strongest predictor of all-cause mortality — stronger than smoking, diabetes, or heart disease as individual risk factors. A landmark study in JAMA found that extreme fitness was associated with the lowest mortality with no upper limit of benefit. You can estimate VO2 max with a timed mile, a rower test, or a wearable. Get faster every year.

𝗡𝘂𝗺𝗯𝗲𝗿 𝗼𝗳 𝗠𝗲𝗱𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀
Target: as few as possible.
Every medication you're on should be earning its place. I just wrote about five commonly prescribed drugs that do more harm than good with long-term use. Bring your full medication list to every appointment. Ask: "Do I still need this?" Deprescribing is one of the most powerful and underused tools in medicine.
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Thirteen numbers. Most available through cheap bloodwork and simple tests. Get them once or twice a year. Here's what I want you to understand: these numbers don't just tell you where you are. They tell you where you're heading. A fasting insulin of 8 today becomes diabetes in five years. An ApoB of 120 today becomes a heart attack in ten. An hs-CRP of 3 today means your arteries are inflamed right now — regardless of how healthy you feel. The standard annual physical checks a fraction of these. It was designed to find disease that's already there. This panel finds the disease that's coming — years before it arrives.

What gets measured gets improved. Optimize with the foundation I write about every week on this platform:
Zone 2 cardio plus resistance training 3-4 times per week. High-protein whole-food nutrition. Sleep 7-9 hours — non-negotiable. Morning sunlight. Stress management. And the targeted supplements I've covered in detail — creatine, magnesium, CoQ10, D3+K2, glycine, omega-3, psyllium husk.
The breakthroughs coming in the next decade — gene editing for cholesterol, cellular reprogramming, senolytics that clear senescent "zombie" cells driving inflammation and aging, GLP-1 drugs rewriting metabolic medicine — will be most powerful for people who've already built the metabolic foundation to receive them.

The future of medicine is personalized. But it starts with knowing your numbers today. Print this list. Book the bloodwork. Own the data. Prevention isn't passive. It's the most aggressive thing you can do for the decades ahead.

[JioHotstar @JioHotstar]

As new enemies emerge and Pandora burns, a new tribe must answer. Avatar: Fire and Ash, now streaming on JioHotstar

[Ashu Bhusari @StartupMantra]

@DeepikaBhardwaj Married on 21st June, 2021.
Separated 1st August 2021.
Fake dowry, harrasment cases.
Divorce case still pending.
Married when 34, now 39 years old.
Wife doesn't appear for case at all.
My friend is living a terrible life.
At this age, he will never have his own children.

[DEVENDRA PRATAP SINGH @FearlessDPSingh]

@DeepikaBhardwaj Such #laws have grossly destroyed the families, bonding & society... nowadays it has been seen a culture of legal #extortion and making life easier & wealthy on the name of #marriages.
Just look at the way, cases are increasing & #greedy have always their own logic to justify it.

[Deepika Narayan Bhardwaj @DeepikaBhardwaj]

MARRIED IN 1984
SEPARATED IN 1990

Wife files 498A in 1992
Husband agrees to pay maintenance

Husband files divorce in 2019
Court grants divorce on ground of cruelty & desertion in 2022, orders 10 Lacs Alimony

Wife moves High Court saying alimony is less

High Court increases Alimony to 40 Lacs saying the woman will have financial & medical needs for atleast 17 more years & she has a right to live the lifestyle she would have lived had she been married. And as the man will received 38 Lacs of retirement benefits, 40 Lacs Alimony is fair and reasonable.

An entire life gone for a marriage that lasted only 6 years where there are no children born. The woman has gone on taking money from this man for the last 34 years and now she gets a lumpsum of 40 Lacs for doing nothing while the man slogged his life to get this retirement benefits of 38 Lacs

Jharkhand High Court is passing such terrible orders that it is appalling. It is quite clear that marriage for them is a lifelong financial bondage for a husband. Whether the man won divorce on merits, whether the man is the victim, whether the man suffered for years - HE HAS TO PAY!!

Honestly , this is literally pushing people to the edge. I can only wonder what I would do if something like this is done to me.

This woman contributed nothing to that man's life. He would have been a free man in 40 years no matter what crime he committed. But he duly followed the law and look what the law does to him

THIS IS SICK. THIS IS SO SICK.

[Felipe Demartini @namcios]

O Google acabou de transformar mais de 1 bilhão de computadores em depósito de IA.

Inclusive o seu.

Sem pedir. Sem avisar. Sem um único popup.

O Chrome baixou 4GB de modelo de inteligência artificial no seu disco. O arquivo se chama weights.bin, são os pesos do Gemini Nano. Fica numa pasta chamada OptGuideOnDeviceModel dentro do seu perfil do Chrome.

Você não autorizou nada. Até existe uma configuração para impedir, mas tá enterrada em submenus que ninguém encontra. E as AI features vêm ligadas por padrão.

Se você deletar o arquivo, o Chrome baixa de novo. Sozinho. Em silêncio. Você decide o que fica no seu disco e o navegador simplesmente ignora.

Funciona assim em Windows, macOS e Ubuntu. Logs forenses no macOS mostram que o arquivo foi instalado dia 24 de abril de 2026, misturado com patches de segurança. Desenvolvedores dizem que isso já rola há mais de um ano.

E tem um detalhe que deixa tudo mais ridículo:

O Chrome 147 coloca um botão "AI Mode" na barra de endereço. Você vê aquilo, sabe que tem modelo de IA no seu computador, e assume que suas buscas rodam localmente.

Não rodam. O AI Mode é 100% cloud. Tudo vai para os servidores do Google. O modelo de 4GB no seu disco não tem nada a ver com aquele botão.

Ele serve para quê? "Help me write" e detecção de scam. Coisas que vivem em submenus de clique-direito que você provavelmente nunca abriu.

O Google ocupou 4GB do seu disco sem pedir, para rodar coisas que quase ninguém usa, enquanto a IA que você de fato vê manda tudo para a nuvem.

Na Europa, pesquisadores já apontam violação do Artigo 5(3) da Diretiva ePrivacy, que exige consentimento antes de armazenar software no dispositivo do usuário.

Como desativar:

→ chrome://flags
→ Busque "Optimization Guide On Device Model"
→ Desative
→ Reinicie o Chrome
→ Delete a pasta OptGuideOnDeviceModel

Seu computador só é seu se você ficar de olho.

[KUNDAN PATEL @KUNDAN00PATEL]

VARANASI 📍

विदेशी आया देखा और समझ गया जो हम सालों में
नहीं समझ पाए भक्ति सिर्फ हाथ जोड़ने में नहीं जगह
साफ रखने में भी होती है ,

विदेशी होकर सेवा को भक्ति बना लिया सफाई को कर्म
मानकर सच्ची सेवा का अर्थ समझा रहा है,

[Sarthak Bhagat @sarthakbhagat45]

One of my followers reached out to me regarding an urgent case.

Pragya Singh (29) is missing while travelling on Nanda Devi AC SF Express (Train 12402, B2/64) from Dehradun to Ghaziabad. Last seen near Roorkee around 1: 30 AM. Her phone is switched off.

It has been over 20 hours with no serious action. Requesting immediate CCTV tracking and investigation.

Details: Pink suit | PNR: 2834728976
📞 9109104394 / 9956793481 / 7985366726

Please act urgently.

@RailMinIndia @IRCTCofficial @RPF_INDIA @AshwiniVaishnaw

[Rahul Kumar @MukAn_X]

चश्मा लगाए इस परेशान शख्स का नाम प्रवीण कुमार है।

इनके साथ बाइक इंश्योरेंस का मामला बिल्कुल एक स्कैम जैसा हो गया है।

इन्होंने 2024 में एक स्कूटी खरीदी थी, जिसका 2 साल का इंश्योरेंस था।

जब इंश्योरेंस खत्म होने वाला था, उसी समय नेशनल इंश्योरेंस वाले एजेंट ने इनसे इंश्योरेंस करने को कहा।

इन्होंने अपनी पूरी स्कूटी का बीमा करवा दिया।

फिर इनका स्कूटी एक्सीडेंट हो गया।

ये इंश्योरेंस वाले के पास गए, तो उसने पूछा कहाँ गिरे, कैसे गिरे? स्टाम्प करवा कर लाओ।

इन्होंने सब किया, तब जाकर सर्वेयर आया यानी चेक करने वाला और वो देख कर गया।

फिर भी तुरंत नहीं बल्कि काफी दिन बाद अप्रूवल मिला।

फिर ये स्कूटी ठीक करवाने गए तो वहां 27,000 का बिल आया।

इन्होंने जब इंश्योरेंस वाले को बताया तो उसने कहा इतना नहीं, बस 15,600 का काम करवाओ, हम इतना ही देंगे।

ये बेचारे फिर भी मान गए।

स्कूटी बन गई और जब पैसे की बारी आई तो इंश्योरेंस वाले ने कहा आप पेमेंट उधर खुद से करो, अपना यही नियम है।

मैं आपके अकाउंट में दूंगा।

इन्होंने खुद से 15600 का पेमेंट किया।

इसके बाद इंश्योरेंस कंपनी से ये रोज पैसे का इंतजार करते रहे पर पैसा नहीं आया।

ये रोज पूछते और हर बार बात को टाल दिया जाता।

करीब 15 दिन के बाद इनके खाते में मात्र 8,238 रुपए आया।

ये जब पूछने गए कि इतना कम क्यों आया, जबकि 15,600 का अप्रूवल था,

तो इसे घुमाने जाने लगा कि इधर बात करो, उधर बात करो।

अब यह आदमी बहुत ही ज्यादा परेशान है।

[Ramanand @Ramanand06X]

“This case is extremely serious.”

A middle-aged man, a plumber by profession, walks into Canara Bank hoping to get a small loan of ₹60,000…

But what he discovers inside completely shakes him.

According to the bank records, there is already a loan of ₹13.28 crore issued in his name.

Yes, crore.

The man breaks down in tears.
He says, “I have never taken any loan… I have never even shared my documents with anyone.”

Imagine the fear.

A person who earns daily wages… suddenly being shown as a defaulter of crores.
No system should allow something like this to happen.

This is not just a clerical error — this is a massive failure of verification, accountability, and data security.

If this can happen to him, it can happen to anyone.

The real question is:
Who approved such a huge loan without proper identity verification?
Where are the checks that are supposed to protect common citizens?

This man isn’t asking for compensation.
He just wants one thing — to clear his name from a loan he never took.

And honestly, that’s the bare minimum he deserves.

Because in a country where financial fraud is rising,
your identity should never become someone else’s opportunity.

[INDIAN MERIT @UnreservedMERIT]

Who is guilty here ...??

Who will return his 20 years of youthful life ..?

A 23-year-old man Vishnu Tiwari was trapped in a false SC/ST case.
For 20 long years he fought in court and finally the court declared him innocent.

But by the time the truth came out, his parents were dead, his brother was gone, and his life was destroyed.

Twenty years stolen.
A family wiped out.
A life ruined.

#SCSTActMisuse

[Parimal @Fintech03]

1 man found 3 yellow grains in the mud & spent 5 yrs protecting them from wild pigs. A trader named the result after his favorite watch brand to prove its quality, while a university stole the seeds to claim the credit. He fed millions, but worked as a daily wage laborer on his own soil. Discover the Ghost Farmer behind India's favorite thin rice.

While the world was looking at high-tech labs for the next green revolution, a school dropout named Dadaji Ramaji Khobragade was standing in his small 1.5 acre plot in Nanded, Maharashtra. While harvesting his usual Patel 3 rice, Dadaji noticed 3 yellow-seeded spikes (lomb) that looked different. Most farmers would have ignored them as impurities.

Dadaji picked those 3 spikes & stored them in a simple plastic bag. For the next 5 yrs, he painstakingly bred them in a tiny patch, protecting them from wild pigs with a fence of thorny bushes. He created a variety that was thinner, smelled better, & yielded 80% more than the conventional seeds.

Dadaji did not have a marketing team/a brand name. In 1990, a large landowner bought 150 kg of these seeds & sold the harvest to a local trader. At that time, HMT Watches were the ultimate symbol of Gold Standard & Reliability in India. The trader, who had recently bought a new HMT watch & was obsessed with it, decided to call the rice HMT Rice simply to signal that this rice was as High Quality as the watch.

The name stuck so hard that people today think HMT Rice was developed by the govt corporation (Hindustan Machine Tools), but the company had absolutely nothing to do with it!

In 1994, the Punjabrao Krishi Vidyapeeth (PKV), an agricultural university, approached Dadaji. They took 5 kg of his seeds under the pretext of experimenting. A few yrs later, the university released a new"variety called PKV-HMT. They claimed Dadaji’s original seeds were impure & that they had purified them.

They took the credit, the patents, & the glory. For yrs, the man who actually did the 5 yrs of backbreaking research was left working as a daily wage laborer on other people’s farms just to feed his family.

Dadaji Khobragade lived in poverty for decades while HMT Rice became a multi-crore industry across Maharashtra, Andhra Pradesh, & Chhattisgarh. It was only much later that the National Innovation Foundation (NIF) stepped in. They proved that the university’s new rice was genetically identical to Dadaji’s.

In 2010, Forbes magazine named him 1 of the most powerful Rural Entrepreneurs, & he finally received a National Award. But by then, he had already sold his own land to pay for his son’s medical treatment. Next time you eat a bowl of thin, aromatic HMT rice, remember it is not the product of a sanitized government lab. It is the result of a man who looked at three tiny yellow grains in the mud & saw a future that the PhDs missed.

The HMT in the rice does not stand for Hindustan Machine Tools; it stands for the Honesty of a Marginalized Toiler. Dadaji Khobragade proved that you do not need a degree to be a scientist; you just need an eye that can see the extraordinary in the ordinary.

A trader's love for a wristwatch gave the rice its name, but a farmer’s love for his land gave the rice its soul. 1 became a brand; the other remained a Ghost in his own fields.

[The Better India @thebetterindia]

A World Cup medal.
And most of us missed it.
India won bronze at the Thomas Cup 2026.

Led by Lakshya Sen, Satwiksairaj Rankireddy and Chirag Shetty—
they finished Top 3 in the world.

And yet… it barely made noise.
In a country where cricket stops traffic,
where every over becomes a headline,
and every win becomes a national mood — a World Cup medal in another sport quietly arrived home.

And maybe that’s the real shift we need—not just cheering wins, but recognising them when they happen.

If this made you pause, share it forward.
Let’s make sure our wins don’t stay silent next time.

@lakshya_sen

#ThomasCup2026 #IndianBadminton #TeamIndia #SportsInIndia #BronzeMedal

[Thomas Cup 2026, Indian Badminton Team, Lakshya Sen, Satwiksairaj Rankireddy, Chirag Shetty, India Bronze Medal]

[Saketh R @saketh1998]

Salary taxation is one of the strangest systems we’ve normalized.

Employees are taxed on income before they can deduct the real cost of earning that income.

But businesses are taxed only after expenses are deducted, on what remains as profit.

Imagine if companies were taxed the way salaried people are: Not on profits, but directly on total revenue, Most of us would call it unsustainable.

Yet for millions of employees, that’s considered completely normal.

[Sann @san_x_m]

Her name is Aradhana Prakash.

She was 14 years old in August 1990. Ruchika Girhotra’s best friend. A fellow tennis trainee at the Haryana Lawn Tennis Association.

She was in the room when S P S Rathore called them both to his office. He sent her out on a pretext. When she returned she found Ruchika distressed.

She was the sole eyewitness. The only person who could testify to what happened that day.

For 19 years Rathore tried to silence her.

He filed civil case after civil case against her family. Cases against journalists covering the story. Cases against the lawyers fighting it.

Ruchika died in December 1993. Her father and brother were harassed so badly they had to leave Panchkula entirely.

Aradhana and her parents stayed.

Her father Anand Prakash and mother Madhu Prakash attended over 400 hearings across 19 years. Every single one. They never settled. They were never intimidated.

The court found Aradhana’s testimony unimpeachable. The judgment relied on her as the sole witness to convict Rathore in December 2009.

When Rathore was attacked outside court by a member of the public she went on television and asked people not to take the law into their own hands. She said that for 19 years they had always worked within the law.

Her father Anand Prakash died of prostate cancer in January 2018 aged 74. He had attended more than 400 hearings. He lived long enough to see Rathore convicted. He did not live long enough to see justice feel complete.

Yesterday, many people here read the story of Ruchika Girhotra for the first time.

Most of them had never even heard her name before.

They should.

Follow for stories India deserves to remember.

[sonali @sonali0_]

A Bank of India employee, sitting there in a red shirt, openly says —

“We won’t do your work… do whatever you can.”

This incident is from the Madhubani branch in Bihar.
A young man went there to open a bank account.
He has been living in Madhubani for the past 5 years, although his permanent home is in Darbhanga.

As per rules, a landlord’s electricity bill from the place where you currently live can be used as valid address proof.
The boy had carried exactly that…

Yet, the bank staff refused straightaway —
👉 “Your account won’t be opened here. Go to Darbhanga.”

The next day, when he returned with another person, the response suddenly changed —

👉 “The account will be opened, but not after 2 PM. That’s the rule.”

Sensing something wrong, the young man immediately called customer care from there.
And the truth came out —
❌ There is no such rule about 2 PM.

When the customer care executive spoke to the bank employee, he blatantly lied —
👉 “He doesn’t have a local address proof.”
Even though the young man was standing there holding the electricity bill.

As soon as the call ended, the same arrogant tone returned —
👉 “Do whatever you want… we will not open your account.”

This is not just negligence — it’s outright misconduct and abuse of power.

Strict action must be taken against such employees. Otherwise, common people will continue to suffer, and trust in the system will keep eroding.

[🚨Indian Gems @IndianGems_]

- Water Issues in Lahuria village, UP for 75 yrs
- New IAS Divya steps in, delivers tap water
- MLA not invited in Jal Ceremony
- MLA complains to CM, Divya transferred.
- Pipeline vandalized by unknown men
- Water stops again.

Well, that's India for you😭

[Wall Street Apes @WallStreetApes]

American bought a brand new printer. She bought the ink for the printer, she bought the paper for the printer, now she’s at home and is ready to print

She can’t print

“They remotely shut off my printer until I paid $7.50 cents to print in my own home, to print on my printer, that I own in my home”

This is the new $7.50 subscription plan by HP Printers

Here’s how the plans work

HP’s Instant Ink and newer All-in Plan programs are subscription services options:

- You pay a monthly fee based on pages printed (not ink used).
- Plans start low, from $1.79–$7.99 per month for 10–100 pages
- $7–$8 per month plans are for around 100 pages

If your payment fails. HP will remotely shutoff your printer

[KV Iyyer - BHARAT 🇮🇳🇮🇱 @BanCheneProduct]

Late Shri Manohar Parrikar Ji once narrated his ordeal.

"I'm from Parra, a village in Goa, so we're called 'Parrikars.' My village is famous for its watermelons. When I was a child, the farmers there held a 'Watermelon Eating Contest' in May, after the harvest. All the children were invited and asked to eat as many watermelons as they wanted.

Many years later, I went to IIT Mumbai to study engineering. Then I returned to my village after 6.5 years. I went to the market to look for watermelons. But they were gone. The ones I found were very small.

I went to meet the farmer who used to hold the 'Watermelon Eating Contest.' Now his son had taken his place. He still held the contest, but there was a difference. When the old farmer offered us watermelons to eat, he would ask us to spit the seeds into a bowl. We were forbidden to chew the seeds. He was collecting seeds for the next crop.

We were, in effect, unpaid child laborers.

He would keep his best watermelons for the competition, using them as the best. He obtained good seeds, which produced even bigger watermelons the next year. When his son arrived, he thought the larger ones would fetch a higher price in the market, so he started selling the larger ones and keeping the smaller ones for competition. The next year, the watermelons grew smaller, and the next even smaller. A watermelon generation lasts one year.

In seven years, Parra's best watermelons were wiped out. In humans, a generation changes every 25 years. In 200 years, we will realize the mistakes we were making in educating our children.

Selecting good seeds, that is, talent, is a huge task in itself. Due to irrelevant ideas and useless things, our good watermelons will go to market, leaving us with useless, inferior seeds.

We must think about this in today's context.