xue liu

Associate Professor at Shenzhen University Medical School
Bacterial pathogenesis (S. pneumoniae, K. pneumoniae), Genetic editing of non-model bacteria

[iMeta @iMetaScience]

Navigating the future of nano‐pesticides: A perspective on design, efficacy, mechanisms, and environmental stewardship
🌱Nano-pesticides are reshaping crop protection toward sustainable agriculture.
https://t.co/zeT5XEpC8r

[xue liu @liuxuescience]

Thrilled to be back in Europe after two years. Especially excited to attend the EMBL Symposium again, first time since 2019! Looking forward to great science and inspiring discussions. #EMBLSymposium #microbiology

[Christian Fankhauser @FankhauserCh]

Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland https://t.co/2lX8eeuBSJ
For a tenure-track Assistant Professor position. More details for how to apply are here https://t.co/nh1saArOWJ

[xue liu @liuxuescience]

@ninatang_ @A_P_S_A @BCM_MSTP @BCMFromtheLabs @DanielCBrock you look awesome!

[iMeta @iMetaScience]

Short‐term #probiotic supplementation affects the diversity, genetics, growth, and interactions of the native gut #microbiome https://t.co/H1iO6mnxe7 #guthealth @wileymicrobio @WileyHealth @WileyBiomedical

[bioRxiv Microbiology @biorxiv_micrbio]

Antibiotics that Kill Gram-negative Bacteria by Restructuring the Outer Membrane Protein BamA https://t.co/PKUNqGhAAx #biorxiv_micrbio

[EMBL-EBI Training @EBItraining]

The @EMBLEvents 2025 Courses and Conferences poster has had an update!

If you're especially interested in training in #datascience #AIinScience #omics and #bioinformatics, take a look at the EMBL-EBI courses here: https://t.co/bgkiER5Nvn

[bioRxiv Microbiology @biorxiv_micrbio]

Tax1bp1 enhances bacterial virulence and promotes inflammatory responses during Mycobacterium tuberculosis infection of alveolar ... https://t.co/iPRMLKs6Wm #biorxiv_micrbio

[Michael Fischbach @mfgrp]

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @DjenetBousbaine led the charge... @Nature 1/55

[Michael Fischbach @mfgrp]

A few notes of gratitude. First, many thanks to @brucegoldman for explaining this so clearly... 52/55
https://t.co/M1Pxf5lmvh

[Coralie Fumeaux @Coralie_Fumeaux]

Hello,
I am looking for a #Postdoctoral researcher with experience in bacterial genetics and antimicrobial resistance. Please send me a CV and a brief summary of your lab experience! Thank you!

[Itai Yanai @ItaiYanai]

The good idea comes when one person feels comfortable enough to say something that might make them look stupid and their friend is open enough to recognize its potential.

[bioRxiv Microbiology @biorxiv_micrbio]

Genome-wide CRISPRi-seq identified ferredoxin-NADP reductase FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa https://t.co/uGIrwcXriG #biorxiv_micrbio

[xue liu @liuxuescience]

Hope our work can contribute a bit to the research related to F. nucleatum.

[xue liu @liuxuescience]

https://t.co/zHlu65AB5v

This collaboration work started 3 years ago and was mainly carried out by a master student Ling Liu, who never knew how to culture bacteria at that time.

[bioRxiv Microbiology @biorxiv_micrbio]

Equip Fusobacterium nucleatum genetic tool kits with compatible shuttle vectors and engineered intermediatory E. coli strains for ... https://t.co/Ghfr1eRDZR #biorxiv_micrbio

[xue liu @liuxuescience]

All the tools developed in this study was shared via the WeKwikgene (https://t.co/Eu4Vs7S1Jg).

[xue liu @liuxuescience]

Additionally, we evaluate promoters with variable strengths with a luciferase-based reporter system in F. nucleatum, providing valuable insights for future gene editing studies in bacterium and contributing to our understanding of its pathogenesis.

[xue liu @liuxuescience]

By exploring the native plasmids from F. nucleatum, we identified new backbones for construction of shuttle vectors and established a dual-plasmid system for the first time, offering new avenues for genetic manipulation in this bacterium.

[xue liu @liuxuescience]

The conjugation-based DNA delivery to F. nucleatum was also established, and this strategy can bypass the requirement of MTase methylations.

[xue liu @liuxuescience]

We employed Pacbio sequencing and identified the active RM systems in F. nucleatum.

Engineered intermediatory E coli strains to expression the Methyltransferases.

Improved the transformation efficiency 1000 fold, reaching 5000 CFU per ug plasmids.