Communicator by trade. Oxford comma enthusiast. Ontario wine advocate. High-speed rail fan. This is a personal account and does not reflect my employer.
At least 10% of the population has a significantly elevated Lp(a) above 50 mg/dL (~125 nmol/L), which carries an increased risk of atherosclerotic cardiovascular disease. While we've known that for decades, we've never had a drug to treat it.
There are 5 programs in advanced trials (Table below, 3 in phase 3, pivotal, CV outcomes as endpoint). We may see the results for the first drug (pelacarsen) soon, by end August, and FDA approval is expected in 2027. This likely represents a major advance for preventing heart disease, adding to the first oral PCSK9 blocker approved this week.
Today, Alto and the Toronto and Region Conservation Authority (@TRCA_HQ) signed a Memorandum of Understanding (MOU).
This agreement reflects our commitment to integrating environmental considerations, watershed management and climate resilience from the earliest stages of high-speed rail development. Grounded in scientific rigour and the protection of natural environments, this partnership provides a framework for environmental planning and assessment activities that will help inform project development.
Learn more: https://t.co/6fWWkTITfe
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Alto et Toronto and Region Conservation Authority (@TRCA_HQ) signent aujourd’hui un protocole d’entente.
Cette entente reflète notre engagement à intégrer les considérations environnementales, la gestion des bassins versants et la résilience climatique dès les premières étapes du développement du réseau de trains à grande vitesse. Ce partenariat, fondé sur la rigueur scientifique et la protection des milieux naturels, sert de base à la mise en place d’activité de planification et d’évaluation environnementale.
Pour en savoir plus : https://t.co/CkZPE1FlXg
By actually making it easy for people in the biggest urban centers of English and French Canada to travel between them and spend time together, high speed rail really probably is one of the ultimate nation building projects.
This morning, a Toronto Police Officer, Constable Marc Pinizzotto, was killed in the line of duty. This tragedy follows the death of OPP Constable Tarun Bali on Tuesday. Canada mourns the loss of these brave officers who dedicated their lives to protecting their communities.
My prayers are with their loved ones, their fellow officers, and their communities in this time of grief.
Fast trains are a great way to travel. But the big upside of Alto lies in the economic boon and housing affordability high-speed rail could deliver, @bruceanderson writes https://t.co/6BS4HvGKXi
Find out more at https://t.co/1zbPY5GAhV
Canada has waited long enough.
GO ALTO launches today as an independent public campaign to make support for ALTO, Canada’s proposed high-speed rail network in the Québec–Toronto corridor, visible.
This is the moment. Let’s build ALTO.
https://t.co/ALRG1jiSHU
It’s going to be a great time to be in the trades.
We’re launching the new Team Canada Strong — a nationwide program to recruit, train, and hire up to 100,000 Red Seal workers who will help build the new homes, railways, and ports that will build Canada strong.
We’re building big in Canada.
Team Canada Strong is a new national effort to make sure young Canadians have the opportunity to secure good, union jobs in the skilled trades.
Long term follow up of a phase 1
trial of an mRNA tumor vaccine shows that 7/8 patients with pancreatic cancer, who mounted an immune response to the vaccine, are still alive 6 years later. This is breathtaking data and shows the promise of mRNA vaccines. https://t.co/J1kDmMRZQY
For on budget/on time, we can all agree that’s what we want to see. If you support ALTO provided that it delivers on budget on time, then support the project and be a voice to make sure that it does. Political opposition won’t make it happen cheaper and faster.
More than 60% of Canadians say they support the ALTO High-speed railway
From Liberals to Conservatives, Canadians want the railway built
Read it for free below
50 years ago today, All the President’s Men (1976) was released.
Still arguably the greatest film about investigative journalism and political thrillers.
“Pierre Poilievre and the Conservatives continue to prove that they’re on the wrong side of history and at odds with the majority of Canadians.”
Cancelling high-speed rail isn’t a vision for the future of Canada https://t.co/rb9zdoDhs8