Long Covid Resources Canada

Directory of resources, research and support for those living with Long Covid and other post-infectious illness in Canada 🇨🇦

[Harshi Peiris, Ph.D. @Neuroscope_mp]

BREAKING 🧵

A gut bacterium is showing up — or rather disappearing — across all three phases of COVID-19.

Severely ill patients have less of it.
Recovered patients get it back.
Long COVID patients don't.

Its name is Faecalibacterium prausnitzii. And what it does explains a lot. 👇

[Hannah Davis @ahandvanish]

New: #LongCovid patients have alterations to the choroid plexus and reduced cerebral blood flow.

The alterations were associated with Alzheimer's markers, including GFAP and p-tau217.

https://t.co/qv9klVg7kI 1/

[Ruth Ann Crystal, MD @CatchTheBaby]

COVID raises your shingles risk.

New data from 110,000+ patients out of Taiwan shows that post-COVID Shingles also raise risk of
➡️ Bell's palsy
➡️ Guillain Barré
➡️ Myasthenia Gravis

Worst of all? Neurological vulnerability lasts for at least 3 years. https://t.co/W2MDpgMdmx

[PolyBio @polybioRF]

Breaking: New PolyBio-supported Study Identifies Microclots, Endothelial Injury Markers and Neutrophil Activation in Children and Young Adults with Long COVID

A new study supported by PolyBio Research Foundation studied children and young adults with Long COVID, providing evidence linking endovascular inflammation, increased quantity and size of fibrin-amyloid “microclots,” and neutrophil activation, and finding detectable Spike protein in a subset.  
https://t.co/hOR1mWHRdc

[Jon Douglas @atranscendedman]

RECOVER Pediatrics, 1,976 children and teens, Long COVID was linked to worse grades, more trouble paying attention, and fewer good moments with friends, suggesting many students may need extra school support.

https://t.co/yItiBWpg6n

[Jon Douglas @atranscendedman]

Charité researchers tracked a 60-year-old woman with long COVID for 3 years and found that spikes in gut permeability matched episodes of chronic fatigue.

Probiotic and medicinal clay treatments reduced symptoms and normalized gut barrier function.

https://t.co/pNzozNtXgw

[PolyBio @polybioRF]

PolyBio’s core team is proud to be working with Invivyd on a clinical trial of the monoclonal VYD2311 for Long Covid and Covid vaccine-injured patients. Dr. Amy Proal, PolyBio CEO and SPEAR founding member stated:“chronic exposure to SARS-CoV-2 spike protein in any form may be driving ongoing morbidity in America, and we believe the mAbs developed by Invivyd may provide an extremely promising route to stopping, and perhaps reversing, some of that damage.”

[Cam Tait @camtait]

TAIT: Province's approach to disabled Albertans falls short https://t.co/kawaJaMvp6 via @

[David Lingenfelter, PhD @dlingenfelter]

Long COVID patients show elevated microclots structurally linked to NETs, driving persistent inflammation.

These biomarkers enable 91% diagnostic accuracy, revealing a thrombo-inflammatory feedback loop behind lasting symptoms.
https://t.co/GuC0DQqDDn

[PolyBio @polybioRF]

CMV infections in the gut have been implicated in a subset of Alzheimer’s disease patients, potentially travelling to the brain via vagus nerve. We are pleased to be supporting Dr. Readhead & his team to develop/validate a biomarker for this Alzheimer’s subset.

https://t.co/6zqxbtJo9P

[Jon Douglas @atranscendedman]

Researchers from Guangzhou University reviewed evidence linking viruses to gut cancers.

At least 25% of people with HIV develop cancer, with higher risk across the GI tract.

SARS-CoV-2 may also raise long-term risk, but evidence is still emerging.

https://t.co/ncnA6gFB1p

[Bateman Horne Center @BatemanHorne]

When a loved one with #MECFS or #LongCOVID experiences a crash, knowing how to respond matters. 💙 Our Caregiver Guidance resource offers practical steps for safe, compassionate support during post-exertional malaise (PEM).

Read it now: https://t.co/4X9tcYqQGm
#UnitedForME

[Long Covid Resources Canada @longcovresource]

As a #LongCovid patient in rural AB since 2020, care has been challenging. Today at the ER I saw a sign in the waiting room, nurses & doctor were all aware of POTS, Dysautonomia, I was treated and referrals were given. Most importantly, they cared and believed me 🙏 @AHS_media

[Bateman Horne Center @BatemanHorne]

1 in 4 people with #MECFS are housebound or bedbound. 💙 @EmergeAus’s evidence-based guide offers strategies for daily care, communication, & managing sensitivity, while protecting both patient & caregiver wellbeing.

Read more: https://t.co/UOImHEH8n1
#UnitedForME

[Jess @MeetJess]

New research out of Mass General Brigham in Boston shows that children born to mothers who had COVID-19 while pregnant face an elevated risk of neurodevelopmental disorders by the time they turn three.
https://t.co/Q3QTRxSlnm

[Long Covid Resources Canada @longcovresource]

Are you living with Long Covid in Canada?

The LC-REVITALIZE clinical trial is now enrolling participants in Montreal and Sherbrooke to test upadacitinib, a med being studied to help LC symptoms. Learn more about the study and how to enroll here👇

https://t.co/pmihm5GekK

[Daniel Park @Daniel_E_Park]

New study evaluating vascular and inflammatory diseases after COVID-19 infection and vaccination in nearly 14 million children.
Large persistent increase in major cardiovascular risks following infection. A small transient myocarditis risk following vaccination

[Billy Hanlon @bhanlon15]

University of Alberta: 'Women are three times more likely than men to get severe long COVID: Here’s why'

"New U of A research reveals underlying mechanisms of how long COVID affects women and men differently"

https://t.co/5CG4SXXwDB

[Eric Topol @EricTopol]

We've just launched the first large, site-less (home, direct to participant) randomized trial for treatment of #LongCovid, testing tirzepatide (a GLP-1 drug) vs placebo. Please help spread the word https://t.co/9xiWw1VdiF

[Paul Keeble ME/LC @PaulRKeeble]

This is a great article on COVID. Increased absences, excess deaths, long COVID including in kids, immune definciences, clea air, N95 guidance for hospitals, links to the studies.

https://t.co/tHgPpzlii6