Longevity Mogul

The science, business, and future of human longevity.

[Longevity Mogul @longevitymogul]

Source: https://t.co/KZQndCpzEc

[Longevity Mogul @longevitymogul]

BREAKING: The first drug discovered and designed using AI has entered Phase 3 human trials.

It's called rentosertib and is being tested for a serious lung disease that causes scarring and makes breathing difficult.

AI discovered both the target and the molecule.

[Longevity Mogul @longevitymogul]

BREAKING: Scientists have developed a treatment for chronic tinnitus using sound and electrical stimulation of the tongue.

In a trial of 300+ adults, 86% of compliant participants saw significant improvement after 12 weeks.

[Smart Science @SmartScience]

A groundbreaking treatment pairing auditory tones with mild electrical shocks rewires the brain to quiet chronic tinnitus.

Chronic tinnitus, the agonizing perception of ringing in the ears without an external sound source, affects millions worldwide and has long eluded effective medical intervention.

However, innovative research in neuroscience shows that bimodal neuromodulation—a technique combining audio tones with gentle electrical stimulation delivered directly to the tongue—can effectively quiet these phantom sounds.

By stimulating touch receptors on the tongue while simultaneously playing targeted acoustic signals through headphones, the treatment leverages the brain's natural neuroplasticity. This dual-sensory approach encourages the central nervous system to reframe its sensory processing, essentially retraining the brain to ignore hyperactive auditory signals.

In a landmark clinical study involving over 300 adults suffering from chronic subjective tinnitus, more than 86% of compliant participants experienced a significant reduction in symptom severity following 12 weeks of daily treatment.

Remarkably, these therapeutic benefits persisted for up to 12 months post-treatment, representing a major leap forward in long-term tinnitus care. Described by patients as feeling like a mild fizzing sensation on the tongue, this non-invasive therapy offers a promising and safe alternative to traditional management strategies, bringing renewed hope to millions seeking lasting relief.

source: Conlon, B., Langguth, B., Hamilton, C., Hughes, S., Meade, E., Connor, C. O., Schecklmann, M., Hall, D. A., Toal, P. D., & Lim, H. H.. Bimodal neuromodulation combining sound and tongue stimulation reduces tinnitus symptoms in a large randomized clinical study. Science Translational Medicine, 12(564).

[Michael Morelli @morellifit]

Today, as featured in Business Insider, we're announcing two things:

1) Choo's story, and how he became "the most measured dog alive."

2) The launch of pawgen, our new dog longevity brand.

A year ago, Choo was slowing down drastically.

I started him on 500 mcg of BPC-157, adjusted for his bodyweight and worked up to 2 mg.

Around week 6 he was running again and got his zest back.

He can't tell me how he feels so I observe and I see less limping, easier breathing, and more energy.

Today, Choo has two vets who make house calls, physical therapy, red light therapy, probiotics, testosterone therapy, etc. We test everything down to heavy metals.

His story went viral, with Business Insider covering it and CBS coming to our house to film a day in his life.

The reality is, most owners can't afford this. A vet visit can cost thousands of dollars whereas a month of peptides often costs under $100.

That's why so many people are turning to them, and also why we're building https://t.co/7i9NbmMbyx - a dog longevity brand helping other dogs get a second chance.

Thanks to Gabby Landsverk and Hilary Brueck at Business Insider for a fair and thorough piece, and to Edward Linsmier for the photos of Choo.

You can read the full article in the link below.

[Save A Man @Save_A_Man]

Want to last longer in bed without killing the vibe?

Here’s what actually works...

[Longevity Mogul @longevitymogul]

As a man,

[Longevity Mogul @longevitymogul]

Not invited = Don‘t go
Not told = Don‘t ask
Late invites = Decline

If you were never part of the plan you've suddenly become a convenience

Respect yourself.

[Longevity Mogul @longevitymogul]

Be a man who has a lot of money, talks less, lives a private life, and minds his own business.

You'll be in the top 1%.

[Longevity Mogul @longevitymogul]

Man to man

[Longevity Mogul @longevitymogul]

As a man, Take your financial life very seriously.
Make a lot of money. Invest. Reinvest and never show off. The world is very cruel to a poor man.

[Longevity Mogul @longevitymogul]

As a man,

[Longevity Mogul @longevitymogul]

Once you realize that anything can happen; sickness, death, lose your job... Literally, anything in the blink of an eye, you become very humble. Tables turn and that's how crazy life can get.

Always pray, stay humble, and be thankful.

[Longevity Mogul @longevitymogul]

As a man,

[Longevity Mogul @longevitymogul]

I don't care what anyone says but money eliminates 97% of your stress.

[Longevity Mogul @longevitymogul]

As a man,

[Longevity Mogul @longevitymogul]

As a man

Having zero health problems is a luxury that people don’t think is a luxury.

Medical bills can bankrupt you.

When you get it all figured out may your health not start troubling you.

[Longevity Mogul @longevitymogul]

As a man,

[Longevity Mogul @longevitymogul]

In this generation, you gotta be the man who has zero desire to be seen. Just busy, paid, hard to reach, and out of sight. You'll go far in life.

[Longevity Mogul @longevitymogul]

Bro to bro

[Longevity Mogul @longevitymogul]

As a man,