A study of the hearts of Greenland sharks has found that the long-lived deep-sea predator has massive accumulations of ageing markers, such as severe scarring, but this doesn't appear to affect their health or longevity
https://t.co/WzdZUV7aRF
Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians
https://t.co/ZsMCi91X80
Western Hunter-Gatherer genetic ancestry contributes to human longevity in the Italian population
In particular, we showed a greater contribution from Western Hunter-Gatherer-related ancestry to Italian centenarians.
https://t.co/CzhsStqObn
World's Healthiest Man Bryan Johnson Achieves 12-Year Biological Age Reversal in Just 500 Days Using HRV Optimization - Health Science Institute https://t.co/HZM6h9TsSg
My magic mushroom longevity experiment found a metabolic reset button in the brain. We expected brain changes, but not a potential metabolic breakthrough.
The discovery: my blood glucose control dramatically improved.
+ before: top 2% of population
+ after: top 0.2% of population
+ better than 99.75% of 18-25 yr olds
+ mean glucose dropped 8%
+ time above 125 mg/dL: zero min
+ variability dropped 11%
This single session reduced my estimated HbA1c by 6.8% from 4.7% to 4.4%.
Why does this matter? We treat diabetes and metabolic dysfunction with chronic daily medication (Metformin, Insulin, GLP-1s). This data suggests that a neuroplastic event might have downstream effects on the liver and pancreas that mimic or exceed these drugs.
For context, taking Metformin daily takes 6 months to drop it 10-15%.
This is a first in-human observation, with comparable pre-clinical evidence existing only in rodents.
Dick Van Dyke, the legendary American actor and comedian who starred in classics such as Mary Poppins and Chitty Chitty Bang Bang, turns 100 on December 13. The beloved actor credits his remarkable longevity to his positive outlook and never getting angry. https://t.co/FX6WFoKibl