Luca Rampoldi

Prof. Medical Genetics @MyUniSR; Group Leader @SanRaffaeleMI

Geneticist by training, with interest in #kidney diseases #ADTKD #UMOD. Views mine

[Luca Rampoldi @lrampold]

🔬Just published in @asnpublications In a mouse model of #ADTKD-UMOD, moderate calorie restriction restores autophagy, reduces ER retention of mutant #uromodulin, and significantly delays kidney disease.

https://t.co/w0TLarLkmT

[ASN Publications @asnpublications]

This #ASNJASN study explored the impact of calorie restriction on Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) caused by UMOD mutations. Read more, and explore #BasicResearch: https://t.co/zEuQCmabUR

[Luca Rampoldi @lrampold]

This work was supported by grants from @Fondaz_Telethon, @MinisteroSalute and @mur_gov_ (PE8–Project @Pe8Age_It: “Ageing Well in an Ageing Society” in the context of the National Recovery and Resilience Plan).

#ADTKD #UMOD #calorierestriction #RareKidneyDisease

[Luca Rampoldi @lrampold]

🔬Just published in @asnpublications In a mouse model of #ADTKD-UMOD, moderate calorie restriction restores autophagy, reduces ER retention of mutant #uromodulin, and significantly delays kidney disease.

https://t.co/w0TLarLkmT

[Luca Rampoldi @lrampold]

Big credit to the brilliant postdoc Mariapia Giuditta Cratere (and her resilience) and to the rest of the team 💪, Benedetta Perrone and Céline Schaeffer at @MyUniSR and @SanRaffaeleMI, and to our collaborator Barbara Canciani at Ospedale Galeazzi - Sant'Ambrogio.

[Sin_Reni @Sin_Reni]

The Italian Society of Nephrology expresses its deep sorrow for the passing of Prof. Claudio Ponticelli, a pioneer in nephrology and an outstanding scientist and mentor. Our heartfelt condolences to his family and colleagues. #RIP #Nephrology

[Luca Rampoldi @lrampold]

@Boletta_Lab @ERC_Research Fantastic, this is a massive achievement! Well done and deserved Ale !! 👏👏

[Luca Rampoldi @lrampold]

Congratulations to @Boletta_Lab and @Ong_Lab ! Well deserved 👏👏👏

[Int Society of Nephrology @ISNkidneycare]

@ananthmsn34 🏅 Dr. Alessandra Boletta (@Boletta_Lab) and Dr. Albert Ong
Winners of the Lillian Jean Kaplan International Prize

[Eric Olinger @ericolinger1]

Happy to share our latest work on UMOD: not just ultrarare or common SNPs! Fantastic collaboration with @lrampold, Celine Schaeffer, @MIKADOlab, @johnasayer and many more! @Kidney_Research @snf_ch

[Massimo Rossi#talebanodiZampini @jurgen_kholer]

@peppebovajena @SandroSca Volevamo la costruzione dal basso porco...

[Luca Rampoldi @lrampold]

@BranwenHennig @wellcometrust Congratulations Branwen !

[Ospedale San Raffaele @SanRaffaeleMI]

#Ricerca - La nuova proteina ingegnerizzata da un nostro gruppo di ricercatori apre potenziali strade verso una nuove strategie terapeutiche rivolte alle distrofie muscolari.
https://t.co/Ib1PeUzDKB

[Luca Jovine → bsky.app/profile/jovinelab.org @lucajovine]

Last May, we were the first to report the #cryoEM structure of #uromodulin, revealing that #zonapellucida domain proteins form filaments with a unique architecture (https://t.co/II3Sp062k2).

Here's the definitive story!

#UMOD #zp_module #zp_domain @karolinskainst @NTUsg

[KDIGO @goKDIGO]

KDIGO is excited to announce Episode 1 of the Genetics in CKD Webinar Series: The Critical Role of Genetics in Rare Kidney Disease - Not Just in Rare Kidney Diseases, on Thursday, July 30th at 11:00 AM EDT. Register: https://t.co/E3dMVZMUor

#kidney #ckd #genetics #nephrology

[Luca Jovine → bsky.app/profile/jovinelab.org @lucajovine]

So here it is - the first long-awaited structure of a ZP module (AKA ZP domain) filament!

Congrats to all my co-workers, and a truly fantastic collaboration with @WUBin10069342, @lrampold, Shigeki Yasumasu & Marta Carroni!!!

#cryoEM #uromodulin #UMOD #zp_domain #zp_module

[Elena Bochukova @ElenaBochukova]

Come and join us @QMULBartsTheLon @blizard_inst !

Looking for a talented geneticis/genomicist to derive functional insights into obesity working closely with @EastLondonGenes! Thanks @Barts_Charity for supporting this post: https://t.co/XRHAu0QohS

Please RT!

[Roberto Buccione, PhD @MacRoboTweet]

Intense, engaging discussion on the use and abuse of social media in science communication and outreach with @Stephen_Curry at the @SanRaffaeleMi Division of Genetics and Cell Biology retreat in beautiful #castione_della_presolana

[Silvia Paracchini @silParacchini]

Great session on 3D chromatin dynamics. Andrey shows v elegantly the role of contact sequences outside enhancers and promoters #ESHG2018

[Rare Disease Day @rarediseaseday]

Rare Disease Day 2018 is on 28 February!
Join us on social media to #ShowYourRare - from face paint selfies to a Thunderclap campaign, there are many creative ways to take part: https://t.co/I51McDo0Q6