🍃➡️🧬 First paper from the Martynowycz Lab!
Spontaneous seed-protein nanocrystals → 0.85Å ab-initio structure of crambin by #MicroED No crystallization screens, no MR bias.
Watch the diffraction-to-density movie & grab the preprint below!
https://t.co/6FJWU5gg4S
Excited to share the N&V @RobertoZoncu and I wrote for @NatureSMB on the recent surge of LYCHOS structure papers! 🚀 We propose a unifying model that ties together these new discoveries. It’s incredible to see so much momentum building on our work.
https://t.co/QqCyCxT0gJ
@bluesocks81@youtubemusic PJ Harvey - Catherine
CCR - Fortunate Son
Metallica - Ride the Lightning
Neil Young - Old man
Chris Cornell - Nearly forgot my broken heart
Tom Waits - Heart attack and vine
@bluesocks81@youtubemusic You've covered a lot of what I'd put down but some additions off the top of my head that have been on my radar lately:
Mulatu Astatke - Nostalgia
Hannes Bieger - Apollo
Toto - Rosanna
Yellow Magic Orchestra - Rydeen
Ben Salter - The Translator
Beastie Boys - Sabotage
Amidst the chaos, here's a belated but exciting highlight on the recent LYCHOS structure by @bj_charles@LuptonCJ @Dr_Ellisdon @Dr_MLHalls@RobertoZoncu and I broke down their findings, explored future directions, and tackled the key remaining questions.
https://t.co/1ECXKjmG3D
We are hiring! The Formosa Group is hiring a Research Officer to join our program on #Mitochondria, #Metabolism & #MitochondrialDisease@MonashBDI!
💡If you're passionate about mitochondrial research or know someone who is, please share! Apply now: https://t.co/l51G65g412
🚨 Save the Date! 🚨
I'm thrilled to announce the Prato Conference on Pore Forming Proteins, happening this June in the stunning city of Prato, Italy!
🙏 Please share or repost this to help us reach as many people as possible—especially those who would love to attend!
🧵 1/ We’re excited to share that our new paper with @adrianbracken lab is out 🎉 In this study (which began 10 years ago!) we explore the biology of PRC2 and PRC1 in non-dividing cells. We also explore the effects of PRC2 inhibitor drugs on these cells. Here’s what we found👇
Thrilled to see our work on high-resolution #cryoem using a common LaB6 120-keV TEM and sub–200-keV direct electron detector, now online @ScienceAdvances. https://t.co/WGbo5j3xWO
. A collaboration with @GatanMicroscopy, @GeorgRamm, and @CryoEM_Monash.
Update! We outline AIVE, an AI method for volume EM data. We show the benefits of AIVE for reconstructing your FIB-SEM data, reveal some fascinating cell biology, and define intrusions as a new form of mitochondrial contact.
https://t.co/nnxj2EB3s2
Muscle mito nanotunnels 1/3🧵
Great to see our work on the #cryoem structure of the human TSC:WIPI3 lysosomal recruitment complex in @ScienceAdvances! Awesome effort from co-authors @bj_charles and @sci_laura with @Dr_Ellisdon doing the heavy lifting leading the project.
https://t.co/n6vfrhHNeM
🚨 Our story on the TSC:WIPI3 lysosomal-recruitment complex is now live in @ScienceAdvances .
Equal-first co-authors @LuptonCJ & @sci_laura. Work lead by @Dr_Ellisdon. Funding from @DeptofDefense & @arc_gov_au.
https://t.co/8JYixZHiQ2
Highlighted today in @CellCellPress a great perspective piece about our recent work on LYCHOS. @arshukla and colleagues raise interesting points about membrane cross talk! https://t.co/HSOb2793Pv
Delighted to share our preview article now published in Cell @CellCellPress where we highlight the beautiful LYCHOS story from @Dr_Ellisdon and team, published recently in @Nature!
Bound by the love for cholesterol: A transporter meets a GPCR: Cell https://t.co/m9AOpxWQFi