Marius Mählen

Former med - now PhD student in the Liberali lab. Loves microscopy, cooking and nerd jokes.

[Marius Mählen @MahlenMarius]

Happy to share our News & Views about the two new papers from @eric_lubeck and @GaublommeL. Congrats 🎉 to the authors for these great achievements in Optical pooled CRISPR screening 🧪🧫 and thanks a lot to @priscaliberali, @KahnwaldMaurice and @KC_Oost! 🧑‍🔬👩‍🔬👨‍🔬

[Nature Biotechnology @NatureBiotech]

@eric_lubeck @TakaKud0 @ProCogia Advances in optical pooled screening to map spatial complexity #NBTNV https://t.co/QZ0QdUNWLZ

[FMI science @FMIscience]

In a Review just published in @CellStemCell, Vladyslav Bondarenko and Margherita Turco explore how stem cell and organoid models can be used and combined to better study the maternal–fetal interface. A 🧵

[Silvia Barbiero @Silvia_Bar01]

We’re excited to share that ez_zarr now supports Zarr v3! 🚀 Huge thanks to @mbstadler & Charlotte Soneson who took on the challenge of creating this open-source tool for fast, programmatic access to OME-Zarr file sets + easy plotting 📊
📄 https://t.co/urfYqDWAuR (1/3)

[D-BSSE, ETH Zurich @ETH_BSSE]

🚀Inaugural lecture of our new faculty member Prisca LIBERALI on ‘The Symphony of Cells: Exploring Self-Organization in Multicellular Systems’ on 7 April 2025 🧬🎶 You missed it? Find the recording 👉🏾 https://t.co/my1WriLWUq
@ETH_en

[D-BSSE, ETH Zurich @ETH_BSSE]

Congratulations to Prisca Liberali, head of the Multicellular Systems Lab @ETH_en, on receiving the Consolidator Grant of the Swiss National Science Foundation #SNSF for her research on the self-organisation of multi-cellular systems!
Find out more > https://t.co/ZOjpb5gl6g

[Prisca Liberali @priscaliberali]

A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration 🧵https://t.co/TZaK4D2isb

[FMI science @FMIscience]

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: https://t.co/9VkmdAZqzP

[FMI science @FMIscience]

In recognition of her groundbreaking research at the FMI, our very own @priscaliberali was awarded the @BaselStadt Science Prize tonight by L.Engelberger,@ConradinCramer, @atici_ch with FMI Director Dirk Schübeler and group leader M. Turco in attendance! https://t.co/hKUz2zNuVp

[FMI science @FMIscience]

Only about a month left to apply to our PhD and MD-PhD programs. Hurry up! Apply at: https://t.co/ejxuqEq0wd

[Nature Biotechnology @NatureBiotech]

Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap https://t.co/kaMbt9yuhC

[Nature Biotechnology @NatureBiotech]

Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView - @eric_lubeck https://t.co/mN2JivaoPC

[Mackenzie Weygandt Mathis, PhD @TrackingActions]

How does sensorimotor (S1/M1) cortex support adaptive motor control? 

Come find out in our latest preprint, which spans the development of a full adult forelimb model + physics simulations, neural-modeling for control, complex 🐭behavior 🕹️, large-scale imaging, and of course @DeepLabCut and @CEBRA! 

We hypothesized that S1 supports motor learning by computing prediction errors. To tackle this, we needed to understand what is being represented, and no studies have reported what forelimb S1 represents during learning in mice🧠🐭. Moreover, this requires modeling the body🦾: kinematics, torques, force, muscle activations, & proprioception (muscle spindles & GTOs). 

After our 7 year journey, we have an answer: S1 & M1 represent muscle-level features. During learning, computational motifs map to functional types (like muscle-encoding), and neural dynamics in S1 change & encode sensorimotor prediction errors! 

https://t.co/IbVeQz3718

🧵👇

[BetzLab @BetzLab]

Paper alert: https://t.co/xJ9figMsyB @NatureMaterials introduces the “Mean Back Relaxation” which quantifies non-equilibrium from simple passive particle trajectories. Amazing theory (M. Krüger, G.Knotz) and experiments @MunkerTill to obtain cell mechanics by simple observation🧐

[Prisca Liberali @priscaliberali]

@schierlab and I are super happy to share this review for the 50th @CellCellPress. We really enjoyed working on it and we hope you will share our excitement for developmental biology: from pattern formation, self organisation and human development! https://t.co/hUF6nU1hVQ

[Marius Mählen @MahlenMarius]

@jvveenvliet @SimonSuppinger @BaCell3D @NARepina_ @laure_plantard Cool, I hope I'll make it, but I'll look out for you :)

[Alex Schier @schierlab]

Developmental Biology is so exciting! @priscaliberali and I had fun writing this review for the 50th anniversary of @CellCellPress about gene regulation, pattern formation, morphogenesis, regeneration, AI, synthetic biology, metabolism, evolution, ecology and many other topics.

[FocalPlane @focalplane_jcs]

In our latest interview we met @joel_luethi & @VirginieUhlmann from the new BioVisionCenter @UZH_en @FMIscience. Throughout the interview their love of bioimage analysis & the community of researchers in this area shone through.
Check it out here:
https://t.co/SBmMNlUypD

[FMI science @FMIscience]

🎥 Researchers at the FMI and @ViventisMicro teamed up to develop a cutting-edge light-sheet microscope that has the potential to transform imaging studies and enable scientific breakthroughs.
@priscaliberali @FranziskaMoos @SimonSuppinger @TsiairisLab

[Prisca Liberali @priscaliberali]

An amazing period for the lab! I would like to thank the @FMIscience and @ETH_BSSE for all the support. I am looking forward to join new colleagues and increase the collaborative environment in Basel that is an incredible scientific hub @IHB_Research @biozentrum @NovartisScience